The feasibility of split liver transplantation (SLT) remains controversial. This study aimed to evaluate the outcomes of SLT in adult recipients and to identify specific areas of improvements. A retrospective analysis was conducted on adults who underwent full size SLT between January 2021 and December 2023. The short-term outcomes of these patients who underwent SLT were compared with those of patients who underwent whole liver transplantation (WLT) during the same period.
Eligibility
Sex
ALL
Min age
16 Years
Max age
75 Years
Healthy volunteers
No
Inclusion Criteria:
* For the donor graft:
1. age of 18-60 years;
2. BMI of 19-28 kg/m2;
3. hemodynamic stability or use of a single vasoactive drug with a small dosage (norepinephrine ≤ 0.1 μg/kg/min or dopamine ≤ 5 μg/kg/min);
4. liver steatosis ≤ 10%;
5. liver functional indicators (ALT, AST, total bilirubin quantification) ≤ 3 times the normal value;
6. blood sodium ≤ 160 mmol/L;
For the SLT recipients
1. Patients who had registered in the China Organ Transplant Response Systems.
2. Initial liver transplantation.
3. Graft-to-Recipient Weight Ratio (GRWR) ≥ 1%.
Exclusion Criteria:
* For the donor graft
1. uncontrollable infection
2. significant vascular and biliary variation.
For the recipients
1. Severe portal hypertension.
2. Significant vascular variation.
Primary outcome measure(s)
Overall survival — 2021.01.01-2025.12.31 the overall survival of liver transplant recipient during study period
Trial sites (1)
Facility
City
Region
Status
Ningbo Medical Centre Lihuili Hospital
Ningbo
Zhejiang
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This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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