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Clinical Trials in China / NCT06919120
Starting soon Phase 4

The Study on the Effect of Different Administration Methods of Simethicone in Reducing Bubbles During Bowel Preparation

NCT06919120 · tracked via the Priya Life Science China tracker
Sponsor
The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Phase
Phase 4
Started
2025-06-01
Last updated
2025-04-09

Condition(s) studied

Colonoscopy

Investigational drug(s) / intervention(s)

Simethicone is mixed into the final packet of compound polyethylene glycol electrolyte powderTake simethicone separately

Simethicone is mixed into the final packet of compound polyethylene glycol electrolyte powder: The patients added one bottle of simethicone when taking the final packet of compound polyethylene glycol electrolyte powder.

Take simethicone separately: Take one bottle of simethicone orally after finishing the last sip of compound polyethylene glycol electrolyte solution.

Study summary

To find the simplest and most effective method of intestinal preparation for dimethicone administration.

Eligibility

Sex
ALL
Min age
18 Years
Max age
80 Years
Healthy volunteers
No
Inclusion Criteria: * Patients undergoing routine colonoscopy at our hospital are aged between 18 to 80 years, including those who meet the Indications for colonoscopy without any absolute contraindications. Exclusion Criteria: * （１） suffering from pancoliنى, intestinal obstruction, toxic megacolon, severe acute gastrointestinal infection, etc.; （２） individuals with severe dysfunction of the heart, lungs, liver, kidneys, etc.; （３） individuals with a history of allergic reaction to the above gastrointestinal agents; （４） individuals who cannot consent to treatment for epilepsy, etc.

Primary outcome measure(s)

  • Boston Bowel Preparation Scale — During the colonoscopy procedure
    Bowel cleanliness was assessed using the Boston Bowel Preparation Scale (BBPS) in both groups, and the efficacy of bowel cleansing was compared between the two medication regimens to identify potential differences
  • Intestinal Bubble Score — During the colonoscopy procedure
    Bowel foam levels were assessed using the Intestinal Bubble Score (IBS) in both groups, and the efficacy of foam clearance was compared between the two medication regimens to identify potential differences

Trial sites (1)

FacilityCityRegionStatus
the Fourth Affiliated Hospital of Zhejiang University Yiwu Zhejiang

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06919120 on ClinicalTrials.gov ↗ ← All trials in China