The EEG Study Under Remimazolam Anesthesia in Children

Condition(s) studied

Study summary

The effect of Remimazolam on brain electrical activity. Previous studies have shown that in healthy male volunteers, EEG changes during Remimazolam infusion are characterized by an initial increase in the beta band and a later increase in the delta band. When monitoring the depth of anesthesia, the commonly used Bispectral Index in clinical practice was originally developed for propofol. Therefore, studies have shown that the correlation between the depth of sedation of benzodiazepines such as midazolam and Bispectral Index is weak. In contrast, the beta wave ratio is considered a more suitable EEG indicator for monitoring the sedative effect of Remimazolam. The above indicates that Remimazolam has a specific pattern of influence on EEG activity, especially in the regulation of anesthesia depth, with unique characteristics.

Eligibility

Primary outcome measure(s)

• Time-frequency characteristics of electroencephalogram (EEG) — Intraoperative (during remimazolam general anesthesia (including anesthesia induction, maintenance and recovery)
  Time-frequency characteristics of electroencephalogram (EEG) in children of different ages during remimazolam general anesthesia (including anesthesia induction, maintenance and recovery) .

Trial sites (1)

More Second Affiliated Hospital of Wenzhou Medical University trials in China

Other trials for the same condition