Hainan Community Cognition Cohort

Condition(s) studied

Investigational drug(s) / intervention(s)

No Intervention: Observational Cohort: There were no interventions in our cohort. The subjects of our cohort were and will be followed up at the regular intervals.

Study summary

This is a community-based prospective cohort study in Hainan Province, China. The study was initialized in 2023 and included older residents for longitudinal follow-up. The research aims to identify risk factors as well as health and social outcomes that are associated with cognitive impairment in elderly populations, and independently develop AI-assisted software and applications for cognitive enhancement and physical rehabilitation training.

Eligibility

Primary outcome measure(s)

• The prevalence and incidence of cognitive impairment base on the communities — An average of 1 to 2 years
  Mild cognitive impairment was measured using a Chinese version Mini-Mental State Examination, which was collected by questionnaire. The minimum value of the Mini-Mental State Examination is 0, and the maximum value is 30, the higher the score, the better the cognition outcome.
• The prevalence and incidence of dementia using a population-based survey — An average of 1 to 2 years
  Dementia was determined by diagnosis of hospitalization or Clinical Dementia Rating Scale (Montreal Cognitive Assessment, MoCA). The minimum value of the MoCA is 0, and the maximum value is 30, the higher the score, the better the outcome. In addition, subtypes of dementia will be based on the specific clinical diagnosis.
• The conversion rate of normal to cognitive impairment — An average of 1 to 2 years
  Percentage of enrolled population that convert from normal to cognitive impairment
• The conversion rate of cognitive impairment to dementia — An average of 1 to 2 years
  Percentage of enrolled population that convert from cognitive impairment to dementia

Trial sites (1)

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