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Clinical Trials in China / NCT06587477
Recruiting Observational

Testicular Function and Semen Quality in Male Childhood and Adolescent Cancer Survivors

NCT06587477 · tracked via the Priya Life Science China tracker
Sponsor
The University of Hong Kong
Phase
Observational
Started
2023-01-16
Last updated
2024-09-19

Condition(s) studied

Cancer, Treatment-RelatedLate EffectSemen Analysis

Investigational drug(s) / intervention(s)

Hormonal profileSemen analysisQuestionnaire

Hormonal profile: Blood for FSH, LH, testosterone

Semen analysis: Semen analysis

Questionnaire: The European Male Ageing Study (EMAS) questionnaire

Study summary

Cancer treatment can affect the testicular function, including sperm and hormonal functions. The aim of this study is to assess the testicular function and semen quality in young men who recover from childhood and adolescent cancer in Hong Kong. This can provide more information for pre-treatment counselling as well as improve post treatment survivorship care. The testicular function will be compared to aged-matched controls from men attending the Family Planning Association for premarital check-up.

Eligibility

Sex
MALE
Min age
18 Years
Max age
50 Years
Healthy volunteers
No
Inclusion Criteria: * Men who have received chemotherapy and/ or radiotherapy for cancer diagnosed when they were \< 18 years old. * \> 18 years old to 50 years old * Cancer in remission for at least 2 years Exclusion Criteria: * Unable to ejaculate by masturbation to provide semen samples * Cryptorchidism, testicular cancer, history of vasectomy * On testosterone replacement therapy * Refusal to join the study

Primary outcome measure(s)

  • Sperm concentration — up to 3 months
    Sperm concentration

Trial sites (1)

FacilityCityRegionStatus
Queen Mary Hospital Hong Kong China Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06587477 on ClinicalTrials.gov ↗ ← All trials in China