Antipsychotic drugs, antidepressants, mood stabilizers, and sleep aids
Antipsychotic drugs, antidepressants, mood stabilizers, and sleep aids: Patients with mental disorders should take the appropriate medicine as prescribed by the doctor，and the health norms are not required to take medicine.This study will not interfere with the medication regimen of doctors.
Study summary
This study focuses on the structure and function of the brain and gene expression in peripheral blood of patients with schizophrenia, to explore the interaction and influence between the three. Patients with mental disorders who have been recruited will take their medication regularly for 1 year and participate in baseline and follow-up assessments.
Eligibility
Sex
ALL
Min age
13 Years
Max age
35 Years
Healthy volunteers
Accepted
Inclusion Criteria:
* Age: 13-35 years old(Patients with healthy siblings can be extended to 14-35 years of age)
* Course of disease: \<24 months
* Priority is given to patients who have never taken medicine or duration of drug use \< 2 weeks
* No nuclear magnetic contraindications.
Exclusion Criteria:
* Family history of psychotic disorders, history of psychoactive substances abuse, alcohol dependence, or nicotine dependence
* Have a major physical disease or infectious disease
* History of coma and serious neurological disease 4.MRI contraindications.
Primary outcome measure(s)
cortical morphology — 40 minutes Data were obtained using magnetic resonance scans
target gene charaacteristics — 1 day 10ml peripheral blood was extracted for gene analysis
scale scores — 90 minutes. The score of each dimension and the total score were calculated according to the scale.The scale includes three dimensions: negative symptom, positive symptom and general psychopathology, and the score range of each dimension is different. The total score ranges from 30 to 210, with higher scores indicating worse results.
Trial sites (1)
Facility
City
Region
Status
The Second Xiangya hospital of central south univerity
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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