Ireland
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Recruiting Observational

Predictive Role of sTREM in Endovascular Thrombectomy Outcomes

NCT06545591 · tracked via the Priya Life Science China tracker
Phase
Observational
Started
2024-07-01
Last updated
2024-08-09

Condition(s) studied

Acute Ischemic Stroke

Study summary

Soluble triggering receptor expressed on myeloid cells (sTREM), which reflects microglia activation, has been reported closely associated with neuronal injury and neuroinflammation. This study is to investigatethe prognostic roles of sTREM (sTREM1 and sTREM2) in patients with ischemic stroke who underwent endovascular thrombectomy (EVT).

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Patients \> 18 years old. * Patients with acute large vessel occlusion within 24 hours of onset who will receive endovascular treatment. Exclusion Criteria: * Impossibility of getting a blood sample. * Impossibility of performing the test (Invalid results). * Refusal to provide the informed consent by the patient/relative.

Primary outcome measure(s)

  • Dynamic changes in plasma levels of sTREM-1 and sTREM-2 following Endovascular Therapy — From baseline to immediately, 24 hours, 3 days, and 7 days after Endovascular Therapy
    Plasma levels of sTREM-1 and sTREM-2 will be quantified using the ELISA method.

Trial sites (1)

FacilityCityRegionStatus
Department of Neurology Xuzhou Jiangsu Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06545591 on ClinicalTrials.gov ↗ ← All trials in China