China Healthy Aging Cohort Study

Condition(s) studied

Investigational drug(s) / intervention(s)

No intervention: No intervention

Study summary

This is a community-based prospective cohort study in China. The study has been initialized in 2024 and included older residents. The goal of this observational study is to explore the risk factors related to disability and dementia in the elderly Chinese community population, and develop a risk prediction model for disability and dementia.

Eligibility

Primary outcome measure(s)

• The prevalence and incidence of functional disability using a population-based survey — An average of 1 to 2 years
  Functional disability was measured by Activities of Daily Living, cognitive function (Mini-Mental State Examination) and movement disorder（Short Physical Performance Battery) collected by questionnaires.The minimum value of the Activities of Daily Living is 0, and the maximum value is 100, the higher the score, the better the outcome.The minimum value of the Mini-Mental State Examination is 0, and the maximum value is 30, the higher the score, the better the outcome.The minimum value of the Short Physical Performance Battery is 0, and the maximum value is 12, the higher the score, the better the outcome.
• The prevalence and incidence of mild cognitive impairment using a population-based survey — An average of 1 to 2 years
  Mild cognitive impairment was measured using Mini-Mental State Examination collected by questionnaire.The minimum value of the Mini-Mental State Examination is 0, and the maximum value is 30, the higher the score, the better the outcome.
• The prevalence and incidence of dementia using a population-based survey — An average of 1 to 2 years
  Dementia was determined by diagnosis of hospitalization or diagnosis of death or Clinical Dementia Rating scale. The minimum value of the Clinical Dementia Rating is 0, and the maximum value is 3, the higher the score, the worse the outcome.
• The conversion rate of normal to mild cognitive impairment — An average of 1 to 2 years
  Percentage of enrolled population that convert from normal to mild cognitive impairment
• The conversion rate of mild cognitive impairment to dementia — An average of 1 to 2 years
  Percentage of enrolled population that convert from mild cognitive impairment to dementia
• The prevalence and incidence of movement disorder using a population-based survey — An average of 1 to 2 years
  Movement disorder was measured using Short Physical Performance Battery collected by questionnaire.The minimum value of the Short Physical Performance Battery is 0, and the maximum value is 12, the higher the score, the better the outcome.

Trial sites (1)

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