Study on Therapeutic Mechanism of Natural Psychotherapy for Neurosis

Condition(s) studied

Investigational drug(s) / intervention(s)

Natural psychotherapy: Draw ideas from traditional Chinese culture, learn from the practice of Morita therapy in Japan, and create local practice experience. At the same time, a variety of research methods such as cognitive assessment and brain imaging were used to establish the scientific, professional and objective evaluation indexes of the therapy.

Study summary

explore objective indicators of the efficacy of natural psychotherapy in the treatment of disorders such as obsessive-compulsive disorder

Eligibility

Primary outcome measure(s)

• Obsessive-compulsive symptoms — Baseline, 12 weeks
  Obsessive-compulsive symptoms were assessed according to the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS), The total score ranges from 0 to 40, with higher scores indicating more severe symptoms.
• Cognitive function — Baseline, 12 weeks
  Cognitive inhibition was assessed using the emotional color-word Stroop task. The emotional Stroop task is a type of being Widely used cognitive inhibition assessment tools. The longer the reaction time, the worse the cognitive inhibition ability.
• Mood and behavior — Baseline, 12 weeks
  Mood changes judged using gait and face recognition
• ERP components associated with cognitive function — Baseline, 12 weeks
  To explore the ERP component analysis related to cognitive inhibition and Behavioral inhibition in obsessive-compulsive disorder (OCD) by event related potential (ERP) analysis
• rest fMRI in Obsessive-compulsive patients — Baseline, 12 weeks
  The changes of resting-state functional connectivity were analyzed in patients with OCD before and after intervention. Resting-state functional connectivity：FC(Functional connectivity). Resting-state functional brain imaging data were collected using a GE 3.0T magnetic resonance scanner (GE Discovery MR750) at the Brain Imaging Center, Institute of Psychology, Chinese Academy of Sciences.
• Behavioral inhibition — Baseline, 12 weeks
  behavioral inhibition was assessed using the emotional stop signal task (SST). The emotional SST task is a type of being Widely used behavioral inhibition assessment tools. Among them, the greater the SSRT, the worse the behavioral inhibition ability.

Trial sites (2)

Other trials for the same condition