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Recruiting Observational

Pre-warning Risk Scoring System for Sudden Cardiac Death

NCT06440083 · tracked via the Priya Life Science China tracker
Phase
Observational
Started
2023-03-02
Last updated
2024-06-05

Condition(s) studied

Sudden Cardiac Death

Study summary

The goal of this observational study is to identify potential indicators for pre-warning of sudden cardiac death (SCD), including clinical biochemistry markers, electrocardiogram, echocardiography, MRI and CT imaging values, genetic markers and so on, and further construct a series of multi-parameter assessments of SCD early screening.

Eligibility

Sex
ALL
Min age
16 Years
Max age
90 Years
Healthy volunteers
Accepted
Inclusion Criteria: The subjects with the following diagnosis of one or more cardiovascular diseases: 1. Coronary heart disease If there is a history of coronary heart disease or a new diagnosis of coronary heart disease, or with a report of coronary angiography that indicates at least one vascular stenosis\>50%. Diagnosis includes chronic coronary syndrome (stable angina, ischemic cardiomyopathy, and occult coronary heart disease) and acute coronary syndrome (unstable angina, ST-segment elevation myocardial infarction and non-ST-segment elevation myocardial infarction). 2. Heart failure Individuals with a history of heart failure or newly diagnosed heart failure, including heart failure with reduced ejection fraction (HFrEF, left ventricular ejection fraction (LVEF) ≤40%)、intermediate heart failure (HFmrEF, LVEF 41%-49%,with evidence of spontaneous or excitable increase in left ventricular filling pressure), and ejection fraction preserving heart failure (HFpEF, LVEF≥50%, there is evidence of spontaneous or excitable increase in left ventricular filling pressure). 3. Genetically related cardiomyopathy or arrhythmia Cardiomyopathy includes hypertrophic cardiomyopathy (DCM), dilated cardiomyopathy (HCM), arrhythmogenic right ventricular cardiomyopathy (ARVC), inflammatory cardiomyopathy (myocarditis, sarcoidosis, Chagas disease). Hereditary arrhythmias include long QT syndrome, short QT syndrome, Brugada syndrome, idiopathic ventricular fibrillation, catecholamine sensitive polymorphic ventricular tachycardia (CPVT), early repolarization syndrome, etc. 2\) Sign an informed consent form. Exclusion Criteria: 1. Age\<16 years old; 2. Refusal to the follow-up visits; 3. Individuals with severe mental disorders who are unable to express their wishes; 4. Other obvious physical diseases and abnormal laboratory test results; 5. Patients deemed unsuitable for participation in this study by the supervising physician.

Primary outcome measure(s)

  • Sudden cardiac death — Baseline and to the 1-year, 2-year, 5-year follow-up
    Identify participants who die by cardiovascular diseases during follow-up period

Trial sites (1)

FacilityCityRegionStatus
Sun Yat-sen Memorial Hospital of Sun Yat-sen University Guanzhou Guangdong Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06440083 on ClinicalTrials.gov ↗ ← All trials in China