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Clinical Trials in China / NCT06368544
Recruiting Not applicable

Effect of Early Gait Training on Knee Cartilage Degeneration After Anterior Cruciate Ligament Reconstruction

NCT06368544 · tracked via the Priya Life Science China tracker
Sponsor
Peking University Third Hospital
Phase
Not applicable
Started
2024-07-22
Last updated
2025-07-25

Condition(s) studied

Anterior Cruciate Ligament InjuriesCartilage Degeneration

Investigational drug(s) / intervention(s)

lower-body positive-pressure

lower-body positive-pressure: By increasing the chamber in the lower body around Pressure acts as a counterweight to gravity

Study summary

A randomized controlled clinical study was conducted to elucidate the relationship between the lower extremity biomechanics of patients undergoing early gait training after ACLR surgery.The relationship between the biochemical characteristics of cartilage and the biomechanical risk index were proposed to providing exercise guidance and training for ACLR people and it is suggested that it can prevent and reduce the risk of cartilage degeneration early after operation.

Eligibility

Sex
ALL
Min age
18 Years
Max age
40 Years
Healthy volunteers
No
Inclusion Criteria: 1. Patients with ACL rupture were diagnosed by MRI; 2. Unilateral ACL rupture for the first time should be performed in our hospital (Department of Sports Medicine, Peking University Third Hospital)The art of reconstruction; 3. Normal BMI range: 18.5-23.9 kg/m2; 4. Within 6 months from the trauma; 5. The affected knee joint has passed the acute stage, no obvious redness, pain,inflammation, and limited joint motion,basically restore joint motion. Exclusion Criteria: 1. BMI\<18.5 kg/m2 or BMI≥24 kg/m2); 2. There is a history of contralateral lower limb musculoskeletal system injury and surgery; 3. ACL injury time \> 6 months; 4. Outerbridge damage rating Ⅲ and Ⅳ; 5. Patients with meniscal tears who are expected to undergo meniscal suture surgery at the time of ACLR surgery; 6. Serious injury to the posterior cruciate ligament, medial collateral ligament, or lateral collateral ligament; 7. There is metabolic syndrome (obesity, dyslipidemia, diabetes, etc.), which will involve articular cartilage Epidemic diseases, serious cardiovascular and cerebrovascular diseases, etc.; 8. Those who do not want to accept this treatment

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Peking University Third Hospital Beijing China Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06368544 on ClinicalTrials.gov ↗ ← All trials in China