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Active, not recruiting Observational

Prognostic Value of the AMR Measured After PPCI in STEMI Patients

NCT05653765 · tracked via the Priya Life Science China tracker
Phase
Observational
Started
2022-12-20
Last updated
2025-03-17

Condition(s) studied

Coronary Heart DiseaseST Elevation Myocardial Infarction

Study summary

The goal of this observational study is to learn about in STEMI with Primary PCI Patients. The main questions it aims to answer are:

* To determine the value of AMR in predicting the long-term clinical prognosis of patients with STEMI after PPCI, and to find the best cut-off value.
* Analyze the factors of PPCI affecting AMR and explore the effective measures of PPCI microcirculation protection.

Radiographic images of STEMI receiving primary PCI treatment in several chest pain centers in China will be included. The last image of the infarct-related vessel will be used as a target to calculate its AMR. The relationship between AMR and long-term clinical prognosis was analyzed.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Aged 18 or older * Type 1 myocardial infarction * Receive PPCI Exclusion Criteria: * Failed to identify culprit vessels. * Structural heart disease with moderate to severe aortic valve or mitral regurgitation and or stenosis that may affect cardiac function * Dialysis patients with severe renal insufficiency * Severe and uncontrollable arrhythmia * Complicated with dilated cardiomyopathy * Unable to tolerate dual antiplatelet therapy * Severe and uncontrollable anemia * Hyperthyroidism * TIMI blood flow 0-1 grade after PPCI

Primary outcome measure(s)

  • MACEs — 12 months
    cardiac death, hospitalization for heart failure, target vessel revascularization,non-fatal MI

Trial sites (5)

FacilityCityRegionStatus
Shangqiu first people's Hospital Shangqiu Henan
Department of Cardiology, First Affiliated Hospital of Xinxiang Medical University Xinxiang Henan
Yongcheng Central Hospital Yongcheng Henan
Fuwai central China cardiovascular Hospital Zhengzhou Henan
Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Shanghai Municipality
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05653765 on ClinicalTrials.gov ↗ ← All trials in China