Lung Health of Early COPD: A Multi-center Cohort Study

NCT05466396 · tracked via the Priya Life Science China tracker

Sponsor

Ting YANG

Phase

Observational

Started

2022-08-01

Last updated

2025-02-17

Condition(s) studied

COPD

Investigational drug(s) / intervention(s)

smoking

smoking: Smoking history and spirometry are used to define groups

Study summary

This is a multi-center, prospective, cohort study in early COPD patients. This study aims to elucidate the lung function decline and its association with smoking and other risk factors. Other biomarkers and image markers from chest CT scan are also analyzed to investigate the lung function in early COPD patients.

Eligibility

Sex

ALL

Min age

35 Years

Max age

75 Years

Healthy volunteers

Accepted

Inclusion Criteria: 1. Gender: male or female 2. Age: 35-75 years old 3. post-bronchodilator spirometry: FEV1/FVC \< 0.8 and FEV1%pred ≥80% Exclusion Criteria: 1. Other diseases may affect lung function, like lung cancer, bronchiectasis, interstitial lung disease or chest surgery. 2. BMI \> 35 kg/m2 3. Dementia or other severe neurological disease 4. Pregnancy 5. Conditions that contraindicated lung function test

Primary outcome measure(s)

Lung function decline in Pre-COPD and Mild-COPD patients — 2 years
FEV1 decline in Pre-COPD and Mild-COPD patients

Trial sites (2)

Facility	City	Region	Status
China-Japan Friendship Hospital	Beijing	Beijing Municipality	Recruiting
Affiliated Hospital of Zunyi Medical University	Zunyi	Guizhou	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05466396 on ClinicalTrials.gov ↗ ← All trials in China