Hematopoietic Stem Cell-containing Autologous Blood Reinfusion for Bone Marrow Protection in Cervical Cancer Patients
Condition(s) studied
Investigational drug(s) / intervention(s)
Autologous blood transfusion with haematopoietic stem cells: Transfusion of autologous blood containing haematopoietic stem cells for haematopoietic reconstruction after chemoradiotherapy.Blood tests were performed weekly, if the patient's neutrophils were less than 1.0 × 109 / L during chemoradiotherapy, G-CSF was given as a remedial treatment. If fever occurs, antibiotics were given promptly.Monitor peripheral blood after transfusion. If peripheral blood leukocyte count does not reach 1.0 x 109/L, administer G-CSF 150 μg subcutaneously daily until peripheral blood leukocyte count reaches 1.0 x 109/L.Patients were tested monthly for peripheral blood cells for 6 months after the end of treatment.
Study summary
The aim of this project is to promote the reconstruction of haematopoietic function after chemoradiotherapy for cervical cancer with the innovative use of autologous haematopoietic containing stem cell blood transfusion support.To explore the effect of stored hemopoietic stem cell support therapy on bone marrow protection after concurrent chemoradiotherapy, in order to promote its clinical application.
Eligibility
Primary outcome measure(s)
- Incidence of Grade 3-4 neutropenia — 6 months
Incidence of Grade 3-4 neutropenia - Time to reconstruct haematopoietic function — 6 months
Time to reconstruct haematopoietic function
Trial sites (1)
| Facility | City | Region | Status |
|---|---|---|---|
| Chongqing University Cancer Hospital | Chongqing | Chongqing Municipality | Recruiting |
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Other trials for the same condition
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT05401175 on ClinicalTrials.gov ↗ ← All trials in China