Treatment of Patients With Takayasu Arteritis Complicated With Pulmonary Artery Involvement

NCT05388682 · tracked via the Priya Life Science China tracker

Sponsor

Chinese Pulmonary Vascular Disease Research Group

Phase

Observational

Started

2014-01-19

Last updated

2023-12-20

Condition(s) studied

Takayasu Arteritis With Pulmonary Artery InvolvementPercutaneous Transluminal Pulmonary AngioplastyPAH Targeted Medication

Investigational drug(s) / intervention(s)

Percutaneous transluminal pulmonary angioplasty

Percutaneous transluminal pulmonary angioplasty: Percutaneous transluminal pulmonary angioplasty

Study summary

1. Evaluate the effect of medical treatment and percutaneous transluminal pulmonary angioplasty on takayasu arteritis with pulmonary artery involvement
2. evaluate the efficacy of FAPI in predicting the activity and treatment efficacy of takayasu arteritis with pulmonary artery involvement

Eligibility

Sex

ALL

Min age

—

Max age

—

Healthy volunteers

Inclusion Criteria: * patients diagnosed with Takayasu arteries with pulmonary arteries involvement Exclusion Criteria: * Patients had pulmonary artery stenosis arising from CTEPH, fibrosing mediastinitis and congenital pulmonary artery stenosis

Primary outcome measure(s)

all cause death — 2014/1/1-2042/12/31
all cause death
mean pulmonary arterial pressure change — 2014/1/1-2042/12/31
change of mean pulmonary arterial pressure after treatment
pulmonary vascular resistance change — 2014/1/1-2042/12/31
chagne of pulmonary vascular resistance after treatment
6MWD change — 2014/1/1-2042/12/31
change of six minute walk distance after treatment
peak VO2 change — 2014/1/1-2042/12/31
change of peak oxygen consumption after treatment
NT-proBNP change — 2014/1/1-2042/12/31
change of NT-proBNP after treatment
RV/LV change — 2014/1/1-2042/12/31
change of right ventricular end-diastolic diameter versus laboratory left ventricular end-diastolic diameterafter treatment
CI change — 2014/1/1-2042/12/31
change of cardiac index after treatment

Trial sites (1)

Facility	City	Region	Status
Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College	Beijing	China	Recruiting

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Other trials for the same condition

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05388682 on ClinicalTrials.gov ↗ ← All trials in China