Second Affiliated Hospital, Zhejiang University, School of Medicine
Phase
Observational
Started
2004-01-01
Last updated
2021-07-16
Condition(s) studied
Wilson Disease
Investigational drug(s) / intervention(s)
low copper diet
low copper diet: All patients with wilson disease should receive low copper diet
Study summary
The investigators aimed to identify factors associated with symptoms and features of Wilson disease from a large cohort during long-term follow-up
Eligibility
Sex
ALL
Min age
6 Years
Max age
65 Years
Healthy volunteers
No
Inclusion Criteria:
* genetically diagnosed patients with wilson disease
Exclusion Criteria:
* Deny follow-up
Primary outcome measure(s)
Serum ceruloplasmin — From 2004 through 2030 Serum ceruloplasmin levels were collected among patients with wilson disease. After confirming a non-Gaussian distribution, the reference range of serum ceruloplasmin level was determined.
Urinary Copper Excretion — From 2004 through 2030 The measurement of 24-hour urine copper excretions were collected and measured.
Kayser-Fleischer Rings — From 2004 through 2030 The presence of Kayser-Fleischer Rings among patients with wilson disease were confirmed via slit lamp.
Brain Magnetic Resonance Imaging — From 2004 through 2030 Brain Magnetic Resonance Imaging of all patients were collected and analyzed.
Trial sites (1)
Facility
City
Region
Status
Second Affiliated Hospital, Zhejiang University School of Medicine
Hangzhou
Zhejiang
Recruiting
More Second Affiliated Hospital, Zhejiang University, School of Medicine trials in China
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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