Clinical Trials in China / NCT04925297
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Observational
Neurological Sequelae in Patients With Acute Carbon Monoxide Poisoning
NCT04925297 · tracked via the Priya Life Science China tracker
Condition(s) studied
Carbon Monoxide Poisoning
Investigational drug(s) / intervention(s)
No intervention
No intervention: No intervention will be given
Study summary
The purpose of this study is to access the clinical characteristics and risk factors for neurological sequelae after acute carbon monoxide poisoning.
Eligibility
Inclusion Criteria:
* patients present within 12 hours after acute carbon monoxide poisoning;
* age older than 16 years.
Exclusion Criteria:
* pregnant women；
* patients receive oxygen therapy before presentation;
* have history of acute carbon monoxide poisoning within 1 year;
* have been diagnosed any of the following disease: Parkinson disease; cognitive disorder, psychiatric disorders, sequelae of cerebral infarction or hemorrhage, chronic kidney disease and receive hemodialysis, congestive heart failure ( NYHA class III-IV)
Primary outcome measure(s)
- Changes of Mini-mental State Examination (MMSE) score at 6 weeks — Changes of score from baseline to 6 weeks
Score ranges from 0 to 30, a lower score means a worse outcome. - Changes of Mini-mental State Examination (MMSE) score at 6 months — Changes of score from baseline to 6 months
Score ranges from 0 to 30, a lower score means a worse outcome. - Changes of Mini-mental State Examination (MMSE) score at 12 months — Changes of score from baseline to 12 months
Score ranges from 0 to 30, a lower score means a worse outcome. - Changes of Montreal cognitive assessment (MoCA）score at 6 weeks — Changes of score from baseline to 6 weeks
Score ranges from 0 to 30, a lower score means a worse outcome. - Changes of Montreal cognitive assessment (MoCA）score at 6 months — Changes of score from baseline to 6 months
Score ranges from 0 to 30, a lower score means a worse outcome. - Changes of Montreal cognitive assessment (MoCA）score at 12 months — Changes of score from baseline to 12 months
Score ranges from 0 to 30, a lower score means a worse outcome. - Changes of Hamilton Depression Scale(HAMD) score at 6 weeks — Changes of score from baseline to 6 weeks
Score ranges from 0 to 54, a higher score means a worse outcome. - Changes of Hamilton Depression Scale(HAMD) score at 6 months — Changes of score from baseline to 6 months
Score ranges from 0 to 54, a higher score means a worse outcome. - Changes of Hamilton Depression Scale(HAMD) score at 12 months — Changes of score from baseline to 12 months
Score ranges from 0 to 54, a higher score means a worse outcome. - Changes of Hamilton Anxiety Scale (HAMA) score at 6 weeks — Changes of score from baseline to 6 weeks
Score ranges from 0 to 56, a higher score means a worse outcome. - Changes of Hamilton Anxiety Scale (HAMA) score at 6 months — Changes of score from baseline to 6 months
Score ranges from 0 to 56, a higher score means a worse outcome. - Changes of Hamilton Anxiety Scale (HAMA) score at 12 months — Changes of score from baseline to 12 months
Score ranges from 0 to 56, a higher score means a worse outcome. - Changes of Activity of Daily Living (ADL) score at 6 weeks — Changes of score from baseline to 6 weeks
Score ranges from 0 to 80, a higher score means a worse outcome. - Changes of Activity of Daily Living (ADL) score at 6 months — Changes of score from baseline to 6 months
Score ranges from 0 to 80, a higher score means a worse outcome. - Changes of Activity of Daily Living (ADL) score at 12 months — Changes of score from baseline to 12 months
Score ranges from 0 to 80, a higher score means a worse outcome. - Changes of self-evaluation of discomfort symptoms scale at 1 week — Changes of score from baseline to 1 week
This is a self designed questionnaire, score ranges from 0 to 66, a higher score means a worse outcome - Changes of self-evaluation of discomfort symptoms scale at 3 weeks — Changes of score from baseline to 3 weeks
This is a self designed questionnaire, score ranges from 0 to 66, a higher score means a worse outcome - Changes of self-evaluation of discomfort symptoms scale at 6 weeks — Changes of score from baseline to 6 weeks
This is a self designed questionnaire, score ranges from 0 to 66, a higher score means a worse outcome - Changes of self-evaluation of discomfort symptoms scale at 6 months — Changes of score from baseline to 6 months
This is a self designed questionnaire, score ranges from 0 to 66, a higher score means a worse outcome - Changes of self-evaluation of discomfort symptoms scale at 12 months — Changes of score from baseline to 12 months
This is a self designed questionnaire, score ranges from 0 to 66, a higher score means a worse outcome
Trial sites (1)
| Facility | City | Region | Status |
|---|---|---|---|
| First Hospital of Jilin University | Changchun | Jilin |
More The First Hospital of Jilin University trials in China
Other trials for the same condition
Official registry record
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT04925297 on ClinicalTrials.gov ↗ ← All trials in China