The First Affiliated Hospital with Nanjing Medical University
Phase
Not applicable
Started
2020-02-01
Last updated
2020-02-05
Condition(s) studied
Myopia, ProgressiveChoroid Disease
Investigational drug(s) / intervention(s)
Optic coherence tomography angiography (OCTA)
Optic coherence tomography angiography (OCTA): Using non-invasive, repeatable, mature device OCTA to obtain choroidal angio-map
Study summary
Myopia is a global healthy concern, especially the high myopia and pathological myopia among Asian populations. However, its mechanism still remains largely unclear. Recent findings suggested choroidal changes might be related to the development of myopia. This study is to useOCT angiography (OCT-A) to investigate parapapillary choroidal microvasculature change in myopic eyes, and try to find the cause-and-effect relationship between choroidal change and the development of myopia.
Eligibility
Sex
ALL
Min age
18 Years
Max age
55 Years
Healthy volunteers
Accepted
Inclusion Criteria:
1. Spherical equivalent measurement can be included in above 4 groups
2. Willing to be followed up in the future 10 years
Exclusion Criteria:
1. Deny to sign the patient consent, or deny to be followed
2. Evidence of cardiac, or diabetic, or CNS disease.
3. Clinically diagnosed with retinal or choroidal disease
4. Glucoma
5. Cataract or corneal disease that influence the quality of fundus OCTA image
Primary outcome measure(s)
Parapapillary choroidal microvasculature void (MvV) area — changes of MvV area from at 10 years area of parapapillary choroidal microvasculature void on OCTA images
Parapapillary choroidal microvasculature void (MvV) area — difference of MvV area in each group at baseline area of parapapillary choroidal microvasculature void on OCTA images
Parapapillary choroidal microvasculature void (MvV) area — changes of MvV area at 1 years area of parapapillary choroidal microvasculature void on OCTA images
Parapapillary choroidal microvasculature void (MvV) area — changes of MvV area at 3 years area of parapapillary choroidal microvasculature void on OCTA images
Parapapillary choroidal microvasculature void (MvV) area — changes of MvV area at 5 years area of parapapillary choroidal microvasculature void on OCTA images
Trial sites (1)
Facility
City
Region
Status
First Affiliated Hospital of Nanjing Medical University
Nanjing
Jiangsu
More The First Affiliated Hospital with Nanjing Medical University trials in China
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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