Outcome of Resection for Colorectal Cancer

Condition(s) studied

Investigational drug(s) / intervention(s)

minimally invasive surgery: Each participating site required accreditation by the trial management committee to ensure proper surgical technique during minimally invasive surgery. No individual surgeons performed only the open approach or only the minimally invasive approach. The committee members reviewed the patients' outcomes and the videos to ensure the adequacy of the surgeon's technique.

Study summary

There are limited data from retrospective studies regarding whether short-term and long-term outcomes after laparoscopic or robot-assisted radical colectomy (minimally invasive surgery) are equivalent to those after open abdominal radical colectomy (open surgery) among patients with early and medium-stage colorectal cancer.

This trial is a multicenter,prospective, randomized trial evaluating short-term and survival outcomes concerning minimally invasive surgery and open surgery for colorectal cancer.

Eligibility

Primary outcome measure(s)

• complications — through hospital stay, an average of two weeks
  complications includes intraoperative and postoperative complications, such as huge blood loss, anastomotic fistula, abdominal infection and septic shock.
• disease free survival — From date of randomization until the date of first documented progression, assessed up to 70 months
  Disease-free survival (DFS) was defined as the interval between the date of surgical resection and diagnosis of recurrence or the most recent follow-up date.
• overall survival — From date of randomization until the date of death from any cause, assessed up to 70 months.
  Overall survival (OS) was measured from the date of hepatectomy to death with or without HCC recurrence or the end of this study period.

Trial sites (1)

More Tianjin Medical University Cancer Institute and Hospital trials in China

Other trials for the same condition