Right Ventricular Function and Respiratory Acidosis After Cardiac Surgery
Condition(s) studied
Investigational drug(s) / intervention(s)
Not applicable- observational study: No intervention
Study summary
Right heart dysfunction remains a frequent cause of morbidity and mortality after cardiac surgery. Respiratory acidosis, particularly when accompanied by hypoxemia, plays a significant role in right heart failure, primarily by increasing right ventricular afterload through pulmonary vasoconstriction and elevated pulmonary arterial pressures. This phenomenon leads to increased right ventricular workload, causing dilation, decreased contractility, and ultimately right heart failure. The study aims to evaluate the effect of respiratory acidosis on right ventricular function after cardiac surgery.
Eligibility
Primary outcome measure(s)
- Right ventricular function per central hemodynamic assessment — At intensive care unit admission - within the first 4 hours
Calculation of different predictor: Cardiac index, PAPi (pulmonary artery pulse pressure over central venous pressure) , RVSWI ((mean pulmonary artery pressure- central venous pressure) X stroke volume index X 0.0136) and RV-CPO
Trial sites (1)
| Facility | City | Region | Status |
|---|---|---|---|
| Institut universitaire de cardiologie et de pneumologie de Quebec - Universite Laval | Québec | Quebec |
More Laval University trials in Canada
Other trials for the same condition
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT07619274 on ClinicalTrials.gov ↗ ← All trials in Canada