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Recruiting Observational

Ketamine Enhances Analgesia and Mood in Chronic Pain Patients

NCT05985811 · tracked via the Priya Life Science Canada tracker
Phase
Observational
Started
2018-02-02
Last updated
2025-01-27

Condition(s) studied

Mood Disorder; OpioidMood Insomnia

Study summary

Most chronic pain patients have mood disorders. The mood disorders may improve with better analgesia produced by Ketamine injections. A prospective study of patients undergoing interventional pain therapy using Ketamine injections. Pre-injection and post-injection patient data is collected. Pain is measured using numeric pain rating scale, and change in pain score by 2-points is considered significant. Sleep is measured using Likert sleep scale, and change in sleep score by 2-points is considered significant. Anxiety is measured using general anxiety disorder (GAD-7) scale, and change in anxiety score by 4-points is considered significant. Depression is measured using patient health questionnaire (PHQ-9), and change in depression score by 5-points is considered significant.

Eligibility

Sex
ALL
Min age
20 Years
Max age
99 Years
Healthy volunteers
Accepted
Inclusion Criteria: * adult chronic pain patients * associated mood disorder * good treatment compliance * associated chronic insomnia * regular ketamine pain therapy injection * consent for clinical record quality assurance review Exclusion Criteria: * severe cognitive disorder * inability to provide consent * major neuropsychiatric disorder * cannabis use * stimulant use * substance abuse * poor treatment compliance * lack of ketamine pain therapy injection

Primary outcome measure(s)

  • Pain score, objective measurement using the validated Numeric Pain Rating scale — 12 weeks
    Pain score, using the Numeric Pain Rating scale of 0 to 10, low scores indicate less pain, high scores indicate worse pain

Trial sites (1)

FacilityCityRegionStatus
Salem Anaesthesia Pain Clinic Surrey British Columbia Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05985811 on ClinicalTrials.gov ↗ ← All trials in Canada