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Clinical Trials in Canada / NCT05522959
Recruiting Observational

Cardio-Oncology Rehabilitation Exercise

NCT05522959 · tracked via the Priya Life Science Canada tracker
Sponsor
University of Toronto
Phase
Observational
Started
2022-03-14
Last updated
2025-10-01

Condition(s) studied

Breast Cancer

Study summary

Women with breast cancer who are referred to the cardiac rehabilitation program at the Toronto Rehabilitation Institute will be invited to enrol in this observational study. Participants will take part in an established 16-week multimodal cardiac rehabilitation program (HEALTh program) at Toronto Rehabilitation Institute and outcome measures will be assessed before and after program participation to determine the effectiveness of the program in improving cardio metabolic health. Change in VO₂peak will be assessed using Cardiopulmonary Exercise Test (CPET). Traditional cardiac risk factors, lifestyle behaviours, exercise adherence, health-related quality of life, and fatigue will also be assessed.

Eligibility

Sex
FEMALE
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * History of early-stage breast cancer (I-III) * Currently receiving or have completed adjuvant therapy (i.e. chemotherapy, surgery, radiation, targeted therapies) * Able to communicate in English Exclusion Criteria: * Pregnancy * Metastatic disease (Stage IV) * Unable or unwilling to complete cardiopulmonary exercise test

Primary outcome measure(s)

  • Cardiopulmonary Fitness — post-intervention (16 weeks)
    VO2peak assessed using cardiopulmonary exercise test

Trial sites (1)

FacilityCityRegionStatus
Toronto Rehabilitation Institute Toronto Ontario Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05522959 on ClinicalTrials.gov ↗ ← All trials in Canada