OptiMized REsistaNt Starch in Inflammatory Bowel Disease: The MEND Trial
Condition(s) studied
Investigational drug(s) / intervention(s)
Resistant Starch: 7.5 g resistant starch/m2 oral consumption
Placebo: Placebo oral consumption of food-grade cornstarch
Study summary
The purpose of the study is to determine if a plant-based resistant starch that is optimized for the individual will target the underlying cause of inflammatory bowel disease and restore a "healthier" gut microbiome in pediatric participants with inflammatory bowel disease.
Eligibility
Primary outcome measure(s)
- Increased potential of butyrate production following the use of individualized resistant starch, as assessed by meta-omics analysis. — 6 ± 1 months
- Sustained potential for butyrate production following 6 months use of individualized resistant starch post randomization as assessed by meta-omics analysis. — 12 ± 2 months
- Change in microbiome composition of cases towards the microbiome of controls as assessed by meta-omics analysis. — 6 ± 1 months and 12 ± 2 months
Trial sites (1)
| Facility | City | Region | Status |
|---|---|---|---|
| Children's Hospital of Eastern Ontario | Ottawa | Ontario |
More Children's Hospital of Eastern Ontario trials in Canada
Other trials for the same condition
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT04520594 on ClinicalTrials.gov ↗ ← All trials in Canada