Upper Airway's Pressure Drop Analyses After Mandibular Advancement and Maxillary Expansion

Condition(s) studied

Investigational drug(s) / intervention(s)

Twin block then Hyrax: Patients will undergo mandibular advancement prior to maxillary expansion

Hyrax then Twin block: Patients will undergo maxillary expansion prior to mandibular advancement

Study summary

Breathing is a crucial function for everyone. Breathing impairment in children could lead to behavioral and cognitive problems at least. But what if orthodontic treatment could help those patients to breathe better, with less effort? This research proposal aims to find out if the increase in the upper airway volume seen in some research results can be related to a decrease in respiratory effort and an improvement in the breathing capacity of those patients. In other words, if a tube shape is changed or if a tube is enlarged, would the airflow passing inside the tube change in velocity? Or would there be more air? Therefore, investigating the pressure/airflow, volume/lumen relation and its possible changes after mandibular repositioning and maxillary expansion in children will lead to a better understanding of how orthodontics could potentially affect the upper airway. Previous studies have reported a link between mandibular advancement appliances and maxillary appliances to an increase in the upper airway volume. However, more studies are needed to evaluate the relationship between the changes in the upper airway volume and actual airflow and respiratory capability. The airway volume measurement is important to, preliminary, state if there is an increase in the upper airway after orthodontic treatment.

However a change in shape, even with the same volume, can affect the pressure and airflow. In this sense, the pressure drop analysis will allow an answer to those questions

Eligibility

Primary outcome measure(s)

• Airflow — 3 years
  Airflow of the upper airway using pressure drop experimental analyzed using the CBCTs scans to print out the models of the upper airway.

Trial sites (1)

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