Visual Memory Training: In the first phase of the study all participants will receive visual memory training. In the second phase they will receive alphabetic search training
Study summary
The current project aims to investigate the trajectories of the visual imaging cognitive training (CT) and alphabet search training using fMRI in patients with amnestic mild cognitive impairment (MCI) and healthy elderly controls (HE). MCI patients will be grouped according to biomarkers (PET PIB).
Eligibility
Sex
ALL
Min age
60 Years
Max age
90 Years
Healthy volunteers
Accepted
Inclusion Criteria:
* Portuguese as native and preferred language; A minimum of 4 years of education; MRI-compatible; Right-handed individuals; Normal corrected vision and hearing; Estimated intelligence average or above (≥ 80 IQ);
Exclusion Criteria:
* History of neurological disorder, severe mental illness; Current untreated alcohol or substance abuse; Medical conditions that compromise in any way the central nervous system; Presence of visual impairment and / or hearing to preclude cognitive testing; Presence of contraindications to MRI exam; Findings in structural MRI that can interfere with the results of the study
Primary outcome measure(s)
Results from task performance in functional magnetic resonance imaging (fMRI) — Baseline, after CT, and 12 months later fMRI behavioral performance
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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