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Clinical Trials in Brazil / NCT07444138
Recruiting Not applicable

Effects of Beetroot Extract on Blood Pressure and Exercise in Hypertensive Older Women

NCT07444138 · tracked via the Priya Life Science Brazil tracker
Phase
Not applicable
Started
2025-10-08
Last updated
2026-03-02

Condition(s) studied

HypertensionHypertension (HTN)

Investigational drug(s) / intervention(s)

Beetroot Extract (Nitrate-rich)PlaceboExerciseRest (Control Condition)

Beetroot Extract (Nitrate-rich): Participants will ingest 2 capsules of a standardized beetroot extract (Berkeley Life Nitric Oxide Foundation). Each dose provides approximately 314 mg of dietary nitrate.

Placebo: Capsules identical in appearance, color, and size to the experimental supplement, but containing an inert substance (starch). This intervention is used to maintain the double-blind design of the study.

Exercise: Participants will perform a single aerobic exercise session on a treadmill. The protocol consists of a 7-minute warm-up followed by 30 minutes of continuous exercise at an intensity corresponding to 60-80% of maximum heart rate (HRmax), estimated using Tanaka's formula (208 - 0.7 \* age). Rate of Perceived Exertion (RPE) will be monitored periodically using the Borg scale (6-20).

Rest (Control Condition): Participants will remain seated for 30 minutes (matching the exercise session duration). During this time, a researcher will administer a Food Frequency Questionnaire (FFQ) in an interview format. This activity serves to assess dietary habits and simulates a routine, low-exertion daily activity (similar to a conversation), acting as a time-matched control for the exercise session.

Study summary

The goal of this clinical trial is to learn about the acute effects of beetroot extract in older women with high blood pressure. The main questions it aims to answer are:

Does beetroot extract affect blood pressure during exercise? Does it change oxygen levels in the muscles? Participants will take a beetroot supplement and perform an aerobic exercise session to check how their bodies respond.

Eligibility

Sex
FEMALE
Min age
60 Years
Max age
—
Healthy volunteers
Accepted
Inclusion Criteria: * Female sex: Older women aged between 60 and 70 years. * Physical capability: Absence of health conditions that could compromise performance in the required physical exercise tests. Exclusion Criteria: * Smoking: Current smokers. * Alcohol use: History of alcohol abuse or excessive alcohol consumption. * Cardiovascular Disease: Diagnosis of cardiovascular diseases (other than the primary condition of hypertension).

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
São Paulo State University (UNESP) Bauru São Paulo Recruiting

More São Paulo State University trials in Brazil

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07444138 on ClinicalTrials.gov ↗ ← All trials in Brazil