A Study to Test Whether BI 3034701 Helps People to Lose Weight Who Live With Obesity or Overweight
Condition(s) studied
Investigational drug(s) / intervention(s)
BI 3034701: BI 3034701
Placebo matching BI 3034701: Placebo matching BI 3034701
Study summary
This study is open to adults between 18 and 74 years of age and who have a body mass index (BMI) of 30 kg/m2 or more, or a BMI of 27 kg/m2 or more and at least 1 health problem related to their weight. People who have previously not managed to lose weight by changing their diet can participate. People with type 2 diabetes cannot take part in this study.
The purpose of this study is to find out whether a medicine called BI 3034701 helps people living with obesity or overweight to lose weight. This study has 7 groups of participants. Groups 1 to 6 get different doses of BI 3034701; Group 7 gets placebo. Placebo looks like BI 3034701 but does not contain any medicine. Every participant has more than an 80% chance of getting BI 3034701. Participants receive 2 injections of BI 3034701 or placebo under their skin for 42 weeks. In addition to the study medicine, all participants receive counselling to make changes to their diet and to exercise regularly.
Participants are in the study for about 10 months. During this time, they visit the study site 15 times. The study doctors regularly measure the participants' body weight and take necessary laboratory tests. Participants also answer questions about their well-being and note their food intake and physical activity in diaries. The results will be compared between groups of participants to see whether the treatment works. The study doctors also regularly check participants' health and take note of any unwanted effects.
Eligibility
Primary outcome measure(s)
- Percentage change in body weight from baseline at Week 42 [%] — Baseline and at Week 42.
Trial sites (54)
| Facility | City | Region | Status |
|---|---|---|---|
| Cahaba Research, Inc. - Trussville Location | Birmingham | Alabama | |
| Focus Clinical Research | West Hills | California | |
| Optimus U Corporation-Miami-69452 | Miami | Florida | |
| Javara-Fayetteville-67354 | Fayetteville | Georgia | |
| Monroe Biomedical Research - Louisville | Louisville | Kentucky | |
| Arcturus Healthcare - Troy Internal Medicine Research Division | Troy | Michigan | |
| StudyMetrix Research, LLC | City of Saint Peters | Missouri | |
| Clinvest Research LLC | Springfield | Missouri | |
| Centricity Research - Morehead City | Morehead City | North Carolina | |
| Accellacare-Wilmington-67123 | Wilmington | North Carolina | |
| Lillestol Research, LLC | Fargo | North Dakota | |
| Tribe Clinical Research at Parkside OB-GYN, Greer | Greer | South Carolina | |
| Texas Diabetes and Endocrinology - Central Austin | Austin | Texas | |
| South Texas Research Institute - Brownsville | Brownsville | Texas | |
| South Texas Research Institute-Edinburg-67012 | Edinburg | Texas | |
| IMA Clinical Research San Antonio | San Antonio | Texas | |
| Data Point Clinical, LLC | Kirkland | Washington | |
| Rainier Clinical Research Center | Renton | Washington | |
| Allegiance Research Specialists | Wauwatosa | Wisconsin | |
| Coastal Digestive Health & CDH Research Institute | Maroochydore | Queensland | |
| Southern Adelaide Diabetes and Endocrine Services (SADES) | Oaklands Park | South Australia | |
| Eastern Health-Box Hill Hospital | Box Hill | Victoria | |
| Ocean West Research Clinic (Surrey) | Surrey | British Columbia | |
| Hilltop Medical Clinic | Surrey | British Columbia | |
| Dr. M. B. Jones Inc. | Victoria | British Columbia | |
| Apex Trials (Guelph) | Guelph | Ontario | |
| Winterberry Research Inc. | Hamilton | Ontario | |
| The Wharton Medical Clinic Clinical Trials Inc. | Hamilton | Ontario | |
| Milestone Research Inc. | London | Ontario | |
| Stouffville Medical Research Institute Inc. | Stouffville | Ontario | |
| Canadian Phase Onward Inc. | Toronto | Ontario | |
| Ecogene-21 | Chicoutimi | Quebec | |
| THEO Medical (Montreal) | Montreal | Quebec | |
| Centre Medical Acadie (9109-0126 Quebec Inc) | Montreal | Quebec | |
| Diex Recherche (Sherbrooke Est) | Sherbrooke | Quebec | |
| Diex Recherche (Victoriaville) | Victoriaville | Quebec | |
| Diex Recherche (Quebec) | Québec | Canada | |
| Huzhou Central Hospital | Huzhou | China | |
| Center Hospital of Jinan | Jinan | China | |
| The First Affiliated Hospital of Henan University of Science and Technology | Luoyang | China |
+ 14 more sites — see the full list on the official registry below.
More Boehringer Ingelheim trials in Australia
Other trials for the same condition
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT07662122 on ClinicalTrials.gov ↗ ← All trials in Australia