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Home›Companies›Mereo BioPharma
Mereo BioPharma logo

Mereo BioPharma

Advancing promising therapies for rare diseases
London, United Kingdom Biotech 100 employees Founded 2015 MREO mereobiopharma.com ↗
7 Products & services
100 Employees

About Mereo BioPharma

Mereo BioPharma is a London-headquartered biopharmaceutical company developing therapeutics for rare and specialty diseases.

Sector
Biotech
Headquarters
London, United Kingdom
Founded
2015
Employees
100

Milestones

Milestones as listed on mereobiopharma.com, checked 26 Sep 2026. Details can change; the linked page is the authoritative source.

2015
Mereo BioPharma founded
Set up to fund and develop high-potential therapies deprioritised by other companies.
Source: mereobiopharma.com
2025
Black Pearl Company Award for Patient Engagement
Received jointly with partner Ultragenyx in February 2025.
Source: mereobiopharma.com
2026
Option and license agreement with Sentynl for alvelestat
Announced August 2026 for AATD-associated lung disease.
Source: mereobiopharma.com

Leadership Team

Leadership as listed on mereobiopharma.com, checked 26 Sep 2026. Details can change; the linked page is the authoritative source.

Dr. Denise Scots-Knight

Chief Executive Officer
Source: mereobiopharma.com

Christine Fox

Chief Financial Officer
Source: mereobiopharma.com

Charles Sermon

General Counsel and Business Development
Source: mereobiopharma.com

Dr. John Lewicki

Chief Scientific Officer
Source: mereobiopharma.com

Dr. Jackie Parkin

Senior Vice President, Therapeutic Head
Source: mereobiopharma.com

Wills Hughes-Wilson

Chief Patient Access and Commercial Planning
Source: mereobiopharma.com

Products & Services

Products and services as listed on mereobiopharma.com, checked 26 Sep 2026. Details can change; the linked page is the authoritative source.

All Rare disease – bone Rare disease – respiratory Out-licensed program Oncology (partnering) Respiratory (partnering)
Rare disease – bone

Setrusumab (UX-143)

Lead program in development for osteogenesis imperfecta, a rare genetic bone condition.

Source: mereobiopharma.com
Rare disease – respiratory

Alvelestat (MPH966)

Lead program for Alpha-1 Antitrypsin Deficiency-associated Lung Disease.

Source: mereobiopharma.com
Out-licensed program

Vantictumab (OMP-18R5)

For potential treatment of autosomal dominant osteopetrosis; partnered with āshibio.

Source: mereobiopharma.com
Out-licensed program

Leflutrozole (BGS649)

For potential treatment of infertility in men with low testosterone; partnered with ReproNovo.

Source: mereobiopharma.com
Out-licensed program

Navicixizumab (OMP305B83)

For potential treatment of post-platinum ovarian cancer; partnered with Feng Biosciences.

Source: mereobiopharma.com
Oncology (partnering)

Etigilimab (MPH313)

For potential treatment of advanced or metastatic solid tumours; open to partnership.

Source: mereobiopharma.com
Respiratory (partnering)

Acumapimod (BCT197)

For potential treatment of acute exacerbations of COPD; open to partnership.

Source: mereobiopharma.com

Financials & Irish Entities

From the annual reports Mereo BioPharma Group plc files with the US Securities and Exchange Commission (10-K, US GAAP), in USD as reported. Latest financial year: to Dec 2025.

$500,000Revenue
$17.8mR&D expense
>999%R&D as % of revenue
−$41.9mNet income (-8,375.6% margin)
Revenue and R&D expense, USD m$0.0m$10m$20m$30mDec 2022Dec 2023Dec 2024Dec 2025Dec 2023: $10m (Revenue)Dec 2025: $0.5m (Revenue)RevenueDec 2022: $29m (R&D expense)Dec 2023: $17m (R&D expense)Dec 2024: $21m (R&D expense)Dec 2025: $18m (R&D expense)R&D expense
RevenueR&D expense
Year toRevenueR&DR&D %Net incomeFiling
Dec 2025$500,000$17.8m>999%−$41.9m10-K 2026
Dec 2024$0$20.9m—−$43.3m10-K 2026
Dec 2023$10.0m$17.4m174.2%−$29.5m10-K 2025
Dec 2022$0$29.5m—−$42.2m10-K 2024

Each year is taken from the most recent annual report that includes it, so earlier years reflect any later restatement. Source: SEC EDGAR (XBRL financial data). Compare companies on the pharma company financials register.

In the News

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Research Publications

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FDA Recalls (US)

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