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Trackers› Clinical trials› USA
Clinical trial register · United States · industry-sponsored

Industry-sponsored studies with a US investigative site

Every industry-sponsored study on the ClinicalTrials.gov registry that lists a US site and is open, about to open, active-but-closed, or enrolling by invitation. This deliberately excludes academic and other non-industry sponsors — the full US registry across all sponsors runs to over 22,000 recruiting studies alone.

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Source: ClinicalTrials.gov. Complete coverage of the industry-sponsored slice — all 9112 matching records are in this view (non-industry sponsors are out of scope by design, not truncated). Synced 23 Sep 2026, 03:16 UTC
9112
Studies in scope
industry-sponsored, all four open statuses
4950
Recruiting now
open to new participants
2202
Lead sponsors
across recruiting studies
Top states
California 5295 Florida 4397 Illinois 2479 Georgia 2346 Arizona 2231
Narrow the register
Recruitment status
Phase
Lead sponsor
AstraZeneca299 Novartis Pharmaceuticals202 Eli Lilly and Company190 Merck Sharp & Dohme LLC183 AbbVie172
State
California5295 Florida4397 Illinois2479 Georgia2346 Arizona2231
All 51 states
Target enrolment
to
9112 of 9112 studies
Download
Status
Study
Lead sponsor
Phase
Enrol
US states
Start
Active, closed
A Clinical Evaluation of the MicroSTent® PeripherAl Vascular SteNt in Subjects With Arterial Disease Below the Knee (STAND)
NCT03477604Peripheral Arterial Disease
Micro Medical Solution, Inc.
Not applicable
177
Alabama, Arizona, California, Colorado, Florida, Iowa, Louisiana, Maryland
2020-03-31
Active, closed
Enfortumab Vedotin and Pembrolizumab vs. Chemotherapy Alone in Untreated Locally Advanced or Metastatic Urothelial Cancer
NCT04223856Urothelial Cancer
Astellas Pharma Global Development, Inc.
Phase 3
886
Arizona, California, Colorado, Connecticut, District of Columbia, Florida, Georgia, Louisiana
2020-03-30
Recruiting
CERAMENT™| Bone Void Filler Device Registry
NCT04244942Orthopedic Disorder
BONESUPPORT AB
Observational
300
Arizona, Florida, Indiana, Kentucky, Massachusetts, New York, North Carolina, Ohio
2020-03-30
Active, closed
Study of Bcl-2 Inhibitor Sonrotoclax (BGB-11417) in Participants With Mature B-Cell Malignancies
NCT04277637Mature B-Cell Malignancies
BeOne Medicines
Phase 1
437
California, Illinois, Kansas, Massachusetts, Minnesota, Nebraska, New Jersey, New York
2020-03-24
By invitation
Stronger Together Global Registry
NCT04364295Spinal Disease
SeaSpine, Inc.
Observational
2,285
Colorado, Ohio
2020-03-20
Active, closed
Study of Posterior Cervical Stabilization System (PCSS) as Part of Circumferential Fusion to Treat Multilevel DDD
NCT04229017Degenerative Disc Disease
Providence Medical Technology, Inc.
Not applicable
236
Arizona, California, Colorado, Illinois, Kentucky, Louisiana, Maryland, Michigan
2020-03-18
Recruiting
A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations
NCT04094610Locally Advanced Solid Tumors, Metastatic Solid Tumors, Lymphoma, Primary CNS Tumors
Turning Point Therapeutics, Inc.
Phase 1/2
75
California, Colorado, Florida, Georgia, Maine, Massachusetts, Missouri, New Jersey
2020-03-12
Active, closed
Pilot Research on Opioid Use Disorder
NCT04244227Opioid-use Disorder
Theranova, L.L.C.
Not applicable
10
California
2020-03-10
Active, closed
A Study to Evaluate Enfortumab Vedotin in Subjects With Locally Advanced or Metastatic Malignant Solid Tumors (EV-202)
NCT04225117Locally Advanced or Metastatic Malignant Solid Tumors
Astellas Pharma Global Development, Inc.
Phase 2
329
Arizona, California, Colorado, Florida, Georgia, Illinois, Indiana, Kansas
2020-03-10
Active, closed
First-in-Human Study of ICT01 in Patients With Advanced Cancer
NCT04243499Solid Tumor, Adult, Hematopoietic/Lymphoid Cancer
ImCheck Therapeutics, an Ipsen company
Phase 1/2
293
Arizona, California, Connecticut, Florida, New York, Texas, Washington
2020-03-05
Recruiting
Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer
NCT04221542Prostate Cancer
Amgen
Phase 1
479
California, Colorado, Connecticut, Georgia, Indiana, Kansas, Louisiana, Missouri
2020-03-04
Active, closed
Study to Evaluate the Safety and Tolerability of FX201 in Patients With Osteoarthritis of the Knee
NCT04119687Osteoarthritis, Knee
Pacira Pharmaceuticals, Inc
Phase 1
72
Arizona, Florida, Missouri, Pennsylvania, Texas
2020-03-02
Recruiting
Study of APG-2575 as a Single Agent or in Combination With Other Therapeutic Agents for CLL/SLL
NCT04215809CLL/SLL
Ascentage Pharma Group Inc.
Phase 1
144
California, Florida, Massachusetts, North Carolina, Ohio, Washington
2020-03-02
Active, closed
GNOS-PV02 Personalized Neoantigen Vaccine, INO-9012 and Pembrolizumab in Subjects With Advanced HCC
NCT04251117HCC
Geneos Therapeutics
Phase 1/2
36
Maryland, New York
2020-03-01
Active, closed
Phase I-II, FIH, TROP2 ADC, Advanced Unresectable/Metastatic Solid Tumors, Refractory to Standard Therapies (KL264-01)
NCT04152499Epithelial Ovarian Cancer, Gastric Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma, Urothelial Carcinoma
Klus Pharma Inc.
Phase 1/2
1,410
California, Florida, Michigan, Oklahoma, Oregon, Texas, Virginia
2020-02-28
By invitation
Survivorship and Effectiveness of the Ortho Development® Entrada™ Hip System for Total Hip Arthroplasty
NCT04277416Total Hip Replacement, Total Hip Arthroplasty
Ortho Development Corporation
Observational
250
Oregon
2020-02-28
Active, closed
FemBloc® Permanent Contraception - Confirmation Feasibility Trial
NCT04273594Contraception
Femasys Inc.
Not applicable
45
Arizona, Georgia, Indiana, Michigan, Ohio
2020-02-27
Active, closed
A Study of NCS-01 in Patients With Acute Ischemic Stroke
NCT03915431Ischemic Stroke
NC Medial Research Inc
Phase 1/2
16
Florida
2020-02-27
Active, closed
Efficacy Against Oral Persistent Infection, Immunogenicity and Safety of the 9-valent Human Papillomavirus Vaccine (9vHPV) in Men Aged 20-45 Years (V503-049)
NCT04199689Papillomavirus Infections
Merck Sharp & Dohme LLC
Phase 3
6,033
California, Florida, Georgia, Idaho, Kansas, Kentucky, Missouri, Nevada
2020-02-27
Active, closed
A Study of Belzutifan (MK-6482) Versus Everolimus in Participants With Advanced Renal Cell Carcinoma (MK-6482-005)
NCT04195750Carcinoma, Renal Cell
Merck Sharp & Dohme LLC
Phase 3
755
Alabama, California, Colorado, District of Columbia, Georgia, Illinois, Louisiana, Maryland
2020-02-27
Recruiting
A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-011 in Patients With Advanced Solid Tumor
NCT04906434Advanced Liver Cancer
Abbisko Therapeutics Co, Ltd
Phase 1
200
Arizona, Florida, Minnesota, New York, Texas
2020-02-26
Active, closed
Study of Romiplostim for Chemotherapy-induced Thrombocytopenia in Adult Subjects With Non-small Cell Lung Cancer (NSCLC), Ovarian Cancer, or Breast Cancer
NCT03937154Chemotherapy-induced Thrombocytopenia
Amgen
Phase 3
145
Arkansas, California, Colorado, Florida, Idaho, Illinois, Louisiana, Maryland
2020-02-26
Active, closed
Safety and Efficacy of IMC-F106C as a Single Agent and in Combination With Checkpoint Inhibitors
NCT04262466Select Advanced Solid Tumors
Immunocore Ltd
Phase 1/2
410
California, Colorado, District of Columbia, Florida, Illinois, Iowa, Massachusetts, New Jersey
2020-02-25
Active, closed
Pulses Consumption and Its Role in Managing Systemic Inflammation, Insulin Sensitivity and Gut Microbiome in Human
NCT04267705Insulin Sensitivity, Overweight or Obesity, Inflammatory Response
Clinical Nutrition Research Center, Illinois Institute of Technology
Not applicable
103
Illinois
2020-02-24
Active, closed
A Study of Subcutaneous Daratumumab Regimens in Combination With Bispecific T Cell Redirection Antibodies for the Treatment of Participants With Multiple Myeloma
NCT04108195Multiple Myeloma
Janssen Research & Development, LLC
Phase 1
290
California, New York, North Carolina, Pennsylvania, Tennessee, Wisconsin
2020-02-21
Active, closed
ENB003 Plus Pembrolizumab Phase 1b/2a in Solid Tumors
NCT04205227Cancer, Melanoma, Ovary Cancer, Pancreatic Cancer
ENB Therapeutics, Inc
Phase 1/2
137
California, Texas
2020-02-18
By invitation
Global Utilization And Registry Database for Improved heArt preservatioN
NCT04141605Heart Diseases, Heart Failure, Heart Defects, Congenital
Paragonix Technologies
Observational
3,000
California, District of Columbia, Florida, Indiana, Kansas, Massachusetts, Michigan, New York
2020-02-14
Active, closed
A Study Evaluating Gene Therapy With BB305 Lentiviral Vector in Sickle Cell Disease
NCT04293185Sickle Cell Disease
Genetix Biotherapeutics Inc.
Phase 3
35
Alabama, District of Columbia, Massachusetts, Minnesota, New Jersey, New York, North Carolina, Texas
2020-02-14
Active, closed
Reducing Right Ventricular Failure in Pulmonary Arterial Hypertension (RELIEVE-PAH)
NCT03838445Pulmonary Arterial Hypertension
V-Wave Ltd
Not applicable
9
California
2020-02-14
Active, closed
ZIP Study-OL Study of Safety, PK, Efficacy, PD, Immunogenicity of ATB200/AT2221 in Pediatrics Aged 0 to < 18 y.o. w/LOPD
NCT03911505Pompe Disease (Late-onset)
Amicus Therapeutics
Phase 3
21
Florida, Georgia, Missouri, North Carolina, Ohio, Pennsylvania, Utah, Virginia
2020-02-13
Recruiting
MDR - PMCF Study for Taperloc Complete Stems
NCT04028687Hip Arthritis, Hip Disease, Hip Fractures, Hip Injuries
Zimmer Biomet
Observational
820
Nevada, Texas, Washington
2020-02-13
Active, closed
Prospective Natural History Study of Retinitis Pigmentosa
NCT04285398Retinitis Pigmentosa
SparingVision
Not applicable
82
Pennsylvania
2020-02-12
Active, closed
A Study of Selpercatinib (LY3527723) in Participants With RET-Mutant Medullary Thyroid Cancer
NCT04211337Medullary Thyroid Cancer
Loxo Oncology, Inc.
Phase 3
291
Alabama, California, Georgia, Illinois, Massachusetts, Michigan, New York, Ohio
2020-02-11
Active, closed
ANXA5 M2 Haplotyping in IVF Patients and Embryos
NCT04544462Infertility, Miscarriage, Recurrent, Pregnancy Complications
Genomic Prediction Inc.
Observational
500
New Jersey
2020-02-10
Active, closed
Long-term Follow-up Study of Patients Receiving Onasemnogene Abeparvovec-xioi
NCT04042025Spinal Muscular Atrophy Type I, Spinal Muscular Atrophy Type II, Spinal Muscular Atrophy Type III, SMA
Novartis Gene Therapies
Phase 3
85
California, Colorado, Illinois, Maryland, Massachusetts, Michigan, Missouri, New York
2020-02-10
Active, closed
DS8201a and Pembrolizumab in Participants With Locally Advanced/Metastatic Breast or Non-Small Cell Lung Cancer
NCT04042701Breast Cancer, Non-small Cell Lung Carcinoma
Daiichi Sankyo
Phase 1
115
California, Connecticut, Florida, Maryland, Massachusetts, Missouri, Pennsylvania, Texas
2020-02-10
Active, closed
Longitudinal Coverage With Evidence Development Study on Micra AV Leadless Pacemakers (Micra AV CED)
NCT04235491Bradycardia
Medtronic
Observational
37,000
Georgia
2020-02-06
Recruiting
BS01 in Patients With Retinitis Pigmentosa
NCT04278131Retinitis Pigmentosa
Bionic Sight LLC
Phase 1/2
20
New Jersey
2020-02-06
Active, closed
Optilume™ BPH Catheter System in Men With Symptomatic BPH
NCT04131907Benign Prostatic Hyperplasia
Urotronic Inc.
Not applicable
162
Arkansas, Colorado, Florida, Illinois, Louisiana, Maryland, Nevada, New Jersey
2020-02-05
Recruiting
A Multicenter Cancer Biospecimen Collection Study
NCT04510129Cancer of Head and Neck, Lung Cancer, Nonsmall Cell, Small-cell Lung Cancer, Urothelial Carcinoma
Cofactor Genomics, Inc.
Observational
1,650
California
2020-02-05
Active, closed
Post Market Clinical Follow-Up Study for EVOLUTION® BIOFOAM® Tibia and EVOLUTION® CS/CR Porous Femur
NCT04301622Knee Osteoarthritis, Traumatic Arthritis of Knee, Avascular Necrosis, Degenerative Joint Disease of Knee
MicroPort Orthopedics Inc.
Observational
150
Michigan
2020-02-03
By invitation
A Study to Evaluate the Safety of Exposure to Wegovy During Pregnancy
NCT05503927Pregnancy, Obesity, Overweight
Novo Nordisk A/S
Observational
2,701
Michigan, New Jersey
2020-02-01
Active, closed
A 5-year Superion™ IDS Clinical Outcomes Post-Approval Evaluation (SCOPE)
NCT04192591Lumbar Spinal Stenosis
Boston Scientific Corporation
Not applicable
166
California, Florida, Georgia, Idaho, Illinois, Kansas, Massachusetts, Michigan
2020-01-30
Active, closed
A Study in Which Non-metastatic Castration-resistant Prostate Cancer (nmCRPC) Patients for Whom a Decision to Treat With Darolutamide Has Been Made Before Enrollment Are Observed and Certain Outcomes Are Described
NCT04122976Prostate Cancer
Bayer
Observational
805
Alabama, Arizona, California, Colorado, Florida, Illinois, Indiana, Kansas
2020-01-30
Recruiting
A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain
NCT05986292Osteoarthritis, Knee, Diabetic Neuropathic Pain, Chronic Low-back Pain
Eli Lilly and Company
Phase 2
10,000
Alabama, Arizona, California, Connecticut, Florida, Georgia, Idaho, Illinois
2020-01-30
Active, closed
A Study Evaluating the Efficacy and Safety of Inavolisib + Palbociclib + Fulvestrant vs Placebo + Palbociclib + Fulvestrant in Participants With PIK3CA-Mutant, Hormone Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer
NCT04191499Breast Cancer
Hoffmann-La Roche
Phase 2/3
325
California, Massachusetts, New York, North Carolina, Tennessee, Texas, Washington
2020-01-29
Active, closed
An Open-label, Single-dose Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Brodalumab in Pediatric Subjects
NCT03240809Psoriasis
Bausch Health Americas, Inc.
Phase 4
2
California, Florida, Nevada
2020-01-24
Recruiting
A Study of Nicotinamide With Oral Tetrahydrouridine and Decitabine to Treat High Risk Sickle Cell Disease
NCT04055818Sickle Cell Disease
EpiDestiny, Inc.
Phase 1
20
Illinois
2020-01-24
Recruiting
A Master Protocol (LY900023) That Includes Several Clinical Trials of Drugs for Children and Young Adults With Cancer
NCT05999994Neoplasms, Child, Adolescent
Eli Lilly and Company
Phase 2
105
Alabama, Arizona, California, Colorado, District of Columbia, Florida, Georgia, Illinois
2020-01-22
Active, closed
Post Approval Study (PAS) of the OPTIMIZER Smart and CCM Therapy
NCT03970343Heart Failure
Impulse Dynamics
Observational
620
Arizona, California, Colorado, District of Columbia, Florida, Georgia, Illinois, Indiana
2020-01-21
Recruiting
A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in Patients With Advanced Solid Tumor
NCT04192344Neoplasms, Tenosynovial Giant Cell Tumor
Abbisko Therapeutics Co, Ltd
Phase 1
276
California, Colorado, Georgia, Texas
2020-01-20
Active, closed
MitraClip EXPAND G4 Study
NCT04177394Mitral Valve Regurgitation, Mitral Regurgitation
Abbott Medical Devices
Observational
1,164
Alabama, Arkansas, California, Connecticut, Florida, Illinois, Kansas, Minnesota
2020-01-17
Active, closed
A Study of Selexipag as Add-On Treatment to Standard of Care in Children With Pulmonary Arterial Hypertension
NCT04175600Hypertension, Pulmonary
Actelion
Phase 3
138
Arizona, California, Colorado, District of Columbia, Florida, Indiana, Michigan, Ohio
2020-01-16
Active, closed
A Study to Evaluate Long-term Safety of Zanubrutinib Regimens in Participants With B-Cell Malignancies Who Participated in BeiGene Parent Studies of Zanubrutinib
NCT04170283B-cell Malignancies
BeOne Medicines
Phase 3
955
Arizona, Arkansas, Colorado, Florida, Massachusetts, Michigan, Minnesota, Mississippi
2020-01-16
Recruiting
Autologous huMNC2-CAR44 or huMNC2-CAR22 T Cells for Breast Cancer Targeting Cleaved Form of MUC1 (MUC1*)
NCT04020575Metastatic Breast Cancer
Minerva Biotechnologies Corporation
Phase 1
69
California
2020-01-15
Active, closed
A Study of Tildrakizumab in Pediatric Subjects With Chronic Plaque Psoriasis
NCT03997786Moderate-to-severe Chronic Plaque Psoriasis
Sun Pharmaceutical Industries Limited
Phase 2/3
135
California, Florida, Washington
2020-01-15
Recruiting
Adipose-Derived Biocellular Regenerative Therapy for Osteoarthritis
NCT04238143Osteoarthritis, Osteo Arthritis Knee, Osteo Arthritis Shoulders, Osteoarthritis of Multiple Joints
Healeon Medical Inc
Not applicable
100
California, Montana
2020-01-10
By invitation
LinguaFlex Tongue Retractor (LTR) for the Treatment of OSA and Snoring in Adults
NCT04129229Obstructive Sleep Apnea, Snoring
Linguaflex, Inc.
Not applicable
80
Massachusetts, West Virginia, Wisconsin
2020-01-10
Active, closed
TAK-788 as First-Line Treatment Versus Platinum-Based Chemotherapy for Non-Small Cell Lung Cancer (NSCLC) With EGFR Exon 20 Insertion Mutations
NCT04129502Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)
Takeda
Phase 3
354
California, Florida, Illinois, Maryland, Massachusetts, Tennessee, Virginia
2020-01-10
Active, closed
PROACTIVE-HF IDE Trial Heart Failure NYHA Class III
NCT04089059Heart Failure NYHA Class III
Endotronix, Inc.
Not applicable
738
Alabama, Arizona, California, Colorado, Connecticut, Florida, Georgia, Hawaii
2020-01-10
Recruiting
Study of HQP1351 in Subjects With Refractory CML and Ph+ ALL
NCT04260022Leukemia, Myeloid, Chronic, Myeloid Leukemia, Chronic Myeloid Leukemia, Philadelphia Positive Acute Lymphoblastic Leukemia
Ascentage Pharma Group Inc.
Phase 1
242
Alabama, California, Georgia, Maryland, Ohio, Texas, Washington
2020-01-09
Active, closed
A Study of Ocrelizumab in Children and Adolescents With Relapsing-Remitting Multiple Sclerosis
NCT04075266Multiple Sclerosis
Hoffmann-La Roche
Phase 2
23
Colorado, District of Columbia, Massachusetts, Missouri, Ohio
2020-01-09
Active, closed
Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Endotoxemic Septic Shock in a Randomized, Open-Label Study
NCT03901807Septic Shock, Endotoxemia
Spectral Diagnostics (US) Inc.
Not applicable
150
Alabama, Arkansas, California, Colorado, District of Columbia, Georgia, Louisiana, Massachusetts
2020-01-09
Active, closed
Study to Evaluate the Efficacy and Safety of Lutathera in Patients With Grade 2 and Grade 3 Advanced GEP-NET
NCT03972488Gastro-enteropancreatic Neuroendocrine Tumor
Advanced Accelerator Applications
Phase 3
226
Connecticut, Florida, Iowa, Kentucky, Minnesota, Texas
2020-01-08
Active, closed
A Study of REGN5093 in Adult Patients With Mesenchymal Epithelial Transition Factor (MET)-Altered Advanced Non-Small Cell Lung Cancer
NCT04077099NSCLC
Regeneron Pharmaceuticals
Phase 1/2
95
California, District of Columbia, Florida, Massachusetts, New York, Pennsylvania, Texas
2020-01-07
Recruiting
A Study of BTX-A51 in People With Relapsed or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome
NCT04243785Acute Myeloid Leukemia, Myelodysplastic Syndrome
Edgewood Oncology Inc.
Phase 1
80
California, New York, Texas
2020-01-06
Active, closed
Phase 1/2a Clinical Trial of PR001 (LY3884961) in Patients With Parkinson's Disease With at Least One GBA1 Mutation (PROPEL)
NCT04127578Parkinson Disease
Prevail Therapeutics
Phase 1/2
32
Arizona, California, Colorado, Florida, Illinois, Minnesota, New York, Pennsylvania
2020-01-03
Recruiting
Post Approval Study for Treatment of Drug-resistant Adult and Pediatric Primary FSGS Using the LIPOSORBER® LA-15 System
NCT04065438Focal Segmental Glomerulosclerosis
Kaneka Medical America LLC
Not applicable
35
California, Delaware, Michigan, New York, North Carolina, Ohio, South Carolina, Virginia
2020-01-01
Recruiting
Impact of Help-Seeking Behaviors on Allergic Rhinitis and Mental Health: A Longitudinal Study
NCT06623799Mental Health Conditions, Allergic
QHSLab, Inc.
Observational
200,000
Florida
2020-01-01
Active, closed
Master Protocol to Assess the Safety and Antitumor Activity of Genetically Engineered T Cells in NY-ESO-1 and/or LAGE-1a Positive Solid Tumors
NCT03967223Neoplasms
USWM CT, LLC
Phase 2
103
California, Colorado, Florida, Illinois, Iowa, Massachusetts, Michigan, Minnesota
2019-12-31
Active, closed
Long-term Safety and Efficacy of Nemolizumab With Moderate-to-severe Atopic Dermatitis
NCT03989206Moderate-to-Severe Atopic Dermatitis
Galderma R&D
Phase 3
1,700
Alabama, Arizona, Arkansas, California, Connecticut, Florida, Georgia, Idaho
2019-12-30
Active, closed
A Study of Sasanlimab in People With Non-muscle Invasive Bladder Cancer
NCT04165317Non-muscle Invasive Bladder Cancer
Pfizer
Phase 3
1,068
Arizona, Arkansas, California, Colorado, Florida, Illinois, Louisiana, Maryland
2019-12-30
Active, closed
Study of Anitocabtagene-autoleucel in Participants With Relapsed Refractory Multiple Myeloma
NCT04155749Relapsed and Refractory Multiple Myeloma
Kite, A Gilead Company
Phase 1
40
Illinois, Massachusetts, Wisconsin
2019-12-23
Active, closed
Cusatuzumab in Combination With Background Therapy for the Treatment of Participants With Acute Myeloid Leukemia
NCT04150887Leukemia, Myeloid, Acute
OncoVerity, Inc.
Phase 1
61
California, Kentucky, Michigan, New York, Pennsylvania, Texas, Vermont, Wisconsin
2019-12-23
Active, closed
Open-Label Extension: Tolerability and Effects of ALK-001 on Stargardt Disease (TEASE)
NCT04239625Stargardt Disease, Stargardt Macular Degeneration, Stargardt Macular Dystrophy, Autosomal Recessive Stargardt Disease 1 (ABCA4-related)
Alkeus Pharmaceuticals, Inc.
Phase 2
200
Arizona, California, Colorado, Florida, Indiana, Michigan, New York, Washington
2019-12-20
Active, closed
Tuvusertib (M1774) in Participants With Metastatic or Locally Advanced Unresectable Solid Tumors (DDRiver Solid Tumors 301)
NCT04170153Metastatic or Locally Advanced Unresectable Solid Tumors
EMD Serono Research & Development Institute, Inc.
Phase 1
161
Massachusetts, Texas
2019-12-20
Active, closed
Continued Access of Focal MR-Guided Focused Ultrasound for Localized Intermediate Risk Prostate Lesions
NCT03998657Prostate Cancer
InSightec
Not applicable
14
California, Florida, Massachusetts, Minnesota, New York
2019-12-19
Recruiting
KEYMAKER-U01 Umbrella Master Study: Studies of Investigational Agents With Either Pembrolizumab (MK-3475) Alone or With Pembrolizumab PLUS Chemotherapy in Participants With Non-small Cell Lung Cancer (NSCLC) (MK-3475-U01/KEYMAKER-U01)
NCT04165798Carcinoma, Non-Small-Cell Lung
Merck Sharp & Dohme LLC
Observational
1,065
Arizona, California, District of Columbia, Kentucky, Maryland, Massachusetts, Nebraska, New Hampshire
2019-12-19
Recruiting
KEYMAKER-U01 Substudy 01A: Efficacy and Safety Study of Pembrolizumab (MK-3475) With or Without Chemotherapy When Used With Investigational Agents in Treatment-naïve Participants With Stage IV Non-small Cell Lung Cancer (NSCLC) (MK-3475-01A/KEYMAKER-U01A)
NCT04165070Carcinoma, Non-Small-Cell Lung
Merck Sharp & Dohme LLC
Phase 1/2
450
Arizona, California, District of Columbia, Kentucky, Maryland, Massachusetts, Nebraska, New Hampshire
2019-12-19
Active, closed
Transforaminal Lumbar Interbody Fusion (TLIF)
NCT04073563Degenerative Disease of the Lumbosacral Spine
Medtronic Spinal and Biologics
Not applicable
600
Arizona, California, Colorado, Connecticut, Florida, Illinois, Indiana, Iowa
2019-12-19
Active, closed
Study of Belantamab Mafodotin Plus Standard of Care (SoC) in Newly Diagnosed Multiple Myeloma
NCT04091126Multiple Myeloma
GlaxoSmithKline
Phase 1
118
Kansas, North Carolina, Wisconsin
2019-12-18
Recruiting
Terumo Aortic Global Endovascular Registry
NCT04246463Abdominal Aortic Aneurysm, Thoracic Aortic Aneurysm, Surgery
Vascutek Ltd.
Observational
1,000
California, Colorado, Connecticut, District of Columbia, Florida, Illinois, Indiana, Michigan
2019-12-17
Active, closed
Sotorasib Activity in Subjects With Advanced Solid Tumors With KRAS p.G12C Mutation (CodeBreak 101)
NCT04185883Advanced Solid Tumors, Kirsten Rat Sarcoma (KRAS) pG12C Mutation
Amgen
Phase 1
610
Arizona, California, Colorado, Connecticut, Florida, Georgia, Illinois, Indiana
2019-12-17
Recruiting
A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis
NCT04176198Myelofibrosis
Sumitomo Pharma America, Inc.
Phase 1/2
240
Alabama, Arizona, California, Colorado, Connecticut, Florida, Georgia, Illinois
2019-12-16
Active, closed
A Study of Nofazinlimab (CS1003) in Subjects With Advanced Hepatocellular Carcinoma
NCT04194775Hepatocellular Carcinoma
CStone Pharmaceuticals
Phase 3
534
California, Maryland, Massachusetts, New York
2019-12-13
By invitation
MDR - Comprehensive Primary/Micro Stem & Versa-Dial Ti Humeral Head
NCT04003311Shoulder Pain, Shoulder Injuries, Shoulder Fractures, Shoulder Disease
Zimmer Biomet
Observational
146
Idaho, Michigan, New York, Vermont
2019-12-13
Active, closed
Neuspera's Implantable Sacral Nerve Stimulation System in Patients With Symptoms of Urinary Urgency Incontinence (UUI)
NCT04232696Urinary Urgency Incontinence
Neuspera Medical, Inc.
Not applicable
331
California, Florida, Georgia, Illinois, Indiana, Kansas, Kentucky, Louisiana
2019-12-13
Active, closed
Prophylactic Reinforcement of Ventral Abdominal Incisions Trial
NCT03911700Open Midline Laparotomy
C. R. Bard
Not applicable
477
Arizona, California, Connecticut, Georgia, Illinois, Indiana, Kentucky, Louisiana
2019-12-12
Active, closed
Primary Unloading and Delayed Reperfusion in ST-Elevation Myocardial Infarction: The STEMI-DTU Trial
NCT03947619ST Elevation (STEMI) Myocardial Infarction of Anterior Wall
Abiomed Inc.
Not applicable
527
Alabama, Arizona, California, Colorado, Connecticut, Delaware, District of Columbia, Florida
2019-12-12
Active, closed
A Clinical Trial Evaluating TG4050 in Head and Neck Cancer
NCT04183166Squamous Cell Carcinoma of Head and Neck
Transgene
Phase 1/2
80
Florida
2019-12-12
Active, closed
Cold Agglutinin Disease Real World Evidence Registry
NCT05791708Cold Agglutinin Disease (CAD), Cold Agglutinin Syndrome (CAS)
RECORDATI GROUP
Observational
429
Alabama, California, District of Columbia, Georgia, Illinois, Iowa, Massachusetts, Michigan
2019-12-12
Recruiting
Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial
NCT04097145Tricuspid Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease
Edwards Lifesciences
Not applicable
1,270
Arizona, California, Colorado, Florida, Georgia, Illinois, Indiana, Iowa
2019-12-11
Recruiting
Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)
NCT04198766Solid Tumor, Non-Small Cell Lung Cancer, Head and Neck Cancer, Melanoma
Inhibrx Biosciences, Inc
Phase 1/2
340
California, Florida, Georgia, Illinois, Iowa, Kentucky, Michigan, Minnesota
2019-12-10
Active, closed
A Study of LY3484356 in Participants With Advanced or Metastatic Breast Cancer or Endometrial Cancer
NCT04188548Breast Cancer, Advanced Breast Cancer, Metastatic Breast Cancer, Endometrial Cancer
Eli Lilly and Company
Phase 1
379
Arizona, Arkansas, California, Florida, Georgia, Indiana, Maryland, Massachusetts
2019-12-10
Active, closed
Descartes-08 CAR-T Cells in Generalized Myasthenia Gravis (MG)
NCT04146051Myasthenia Gravis, Generalized
Cartesian Therapeutics
Phase 2
30
California, Colorado, Florida, Georgia, Kansas, New York, North Carolina, Oregon
2019-12-04
Recruiting
Medtronic Cardiac Surgery PMCF Registry
NCT04073420Valve Disease, Heart
Medtronic Cardiac Surgery
Observational
2,700
Georgia, Michigan, New York, North Carolina, Ohio, Pennsylvania, Texas, Virginia
2019-12-02
Recruiting
Registry of Participants With Generalized Myasthenia Gravis Treated With Alexion C5 Inhibition Therapies (C5ITs)
NCT04202341Generalized Myasthenia Gravis
Alexion Pharmaceuticals, Inc.
Observational
500
Alabama, Arizona, California, Colorado, Connecticut, District of Columbia, Florida, Georgia
2019-12-02
Active, closed
Long Term Follow-up on Menkes Disease Patients
NCT04337684Menkes Disease
Sentynl Therapeutics, Inc.
Observational
50
California
2019-12-01
Active, closed
M6-C Post Approval Study (PAS)
NCT04122248Cervical Degenerative Disc Disease, Cervical Radiculopathy, Cervical Spinal Cord Compression, Cervical Disc Herniation
Spinal Kinetics
Observational
152
Arizona, California, Colorado, Connecticut, District of Columbia, Illinois, Indiana, Louisiana
2019-11-30
Active, closed
Study of Subcutaneous (SC) Belimumab in Pediatric Participants With Systemic Lupus Erythematosus (SLE)
NCT04179032Systemic Lupus Erythematosus
GlaxoSmithKline
Phase 2
25
Ohio
2019-11-28
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Priya Life Science (2026). Clinical trial register: industry-sponsored studies with a US investigative site. Derived from ClinicalTrials.gov. Retrieved 23 September 2026. https://priyalifescience.com/clinical-trials-usa?page=83

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