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Trackers› Clinical trials› USA
Clinical trial register · United States · industry-sponsored

Industry-sponsored studies with a US investigative site

Every industry-sponsored study on the ClinicalTrials.gov registry that lists a US site and is open, about to open, active-but-closed, or enrolling by invitation. This deliberately excludes academic and other non-industry sponsors — the full US registry across all sponsors runs to over 22,000 recruiting studies alone.

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Source: ClinicalTrials.gov. Complete coverage of the industry-sponsored slice — all 9110 matching records are in this view (non-industry sponsors are out of scope by design, not truncated). Synced 22 Sep 2026, 03:16 UTC
9110
Studies in scope
industry-sponsored, all four open statuses
4947
Recruiting now
open to new participants
2198
Lead sponsors
across recruiting studies
Top states
California 5292 Florida 4393 Illinois 2478 Georgia 2343 Arizona 2230
Narrow the register
Recruitment status
Phase
Lead sponsor
AstraZeneca299 Novartis Pharmaceuticals202 Eli Lilly and Company190 Merck Sharp & Dohme LLC183 AbbVie172
State
California5292 Florida4393 Illinois2478 Georgia2343 Arizona2230
All 51 states
Target enrolment
to
9110 of 9110 studies
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Status
Study
Lead sponsor
Phase
Enrol
US states
Start
Active, closed
The Synergy Disc To Anterior Cervical Discectomy and Fusion
NCT04469231Cervical Degenerative Disc Disease
Synergy Spine Solutions
Not applicable
175
Arizona, California, Colorado, Florida, Indiana, Michigan, New York, North Carolina
2020-10-30
Active, closed
Study of Efficacy and Safety of LXH254 Combinations in Patients With Previously Treated Unresectable or Metastatic Melanoma
NCT04417621Melanoma
Novartis Pharmaceuticals
Phase 2
134
California, Florida, Massachusetts, Minnesota, New York, Pennsylvania, Texas
2020-10-30
Recruiting
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
NCT04585750Advanced Solid Tumor, Advanced Malignant Neoplasm, Metastatic Cancer, Metastatic Solid Tumor
PMV Pharmaceuticals, Inc
Phase 1/2
300
California, Colorado, Connecticut, Delaware, Florida, Massachusetts, Michigan, Nebraska
2020-10-29
Recruiting
The Tether™ - Vertebral Body Tethering System Post Approval Study
NCT04505579Scoliosis Idiopathic
ZimVie
Observational
200
California, Colorado, Florida, Georgia, Louisiana, Minnesota, Missouri, New York
2020-10-29
Recruiting
Phase 2 Clinical Trial of CartiLife® in the United States
NCT04744402Articular Cartilage Defect, Articular Cartilage Degeneration
Biosolution Co., Ltd.
Phase 2
25
California, Louisiana, Ohio
2020-10-28
Active, closed
Study of Cretostimogene Given in Patients With Non-Muscle Invasive Bladder Cancer ,Unresponsive to Bacillus-Calmette-Guerin
NCT04452591Non Muscle Invasive Bladder Cancer, High-grade Ta/ T1 Papillary Disease Bladder Cancer
CG Oncology, Inc.
Phase 3
190
Alabama, Arizona, Arkansas, California, Colorado, District of Columbia, Florida, Georgia
2020-10-27
Active, closed
Gene Transfer Study in Patients With Late Onset Pompe Disease
NCT04174105Pompe Disease (Late-onset)
Astellas Gene Therapies
Phase 1/2
11
California, Utah
2020-10-27
Active, closed
A Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Ocrelizumab in Adult Participants With Primary Progressive Multiple Sclerosis
NCT04544449Multiple Sclerosis, Primary Progressive
Hoffmann-La Roche
Phase 3
985
Alabama, California, Colorado, Connecticut, District of Columbia, Florida, Indiana, Kansas
2020-10-26
Recruiting
LymphBridge: Surgical Evaluation for Breast Cancer-Associated Lymphedema (BioBridge)
NCT04606030Lymphedema, Edema
Fibralign Corporation
Not applicable
60
Illinois, Texas
2020-10-26
Recruiting
Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms
NCT04541082Central Nervous System Neoplasms, Glioblastoma, Gliosarcoma, Adult, Anaplastic Oligodendroglioma
Jazz Pharmaceuticals
Phase 1
102
Maryland
2020-10-26
Active, closed
Recent-Onset Type 1 Diabetes Extension Study Evaluating the Long-Term Safety of Teplizumab (PROTECT Extension)
NCT04598893Diabetes Mellitus, Type 1
Provention Bio, a Sanofi Company
Observational
188
California, Colorado, Florida, Georgia, Idaho, Indiana, Iowa, Maryland
2020-10-26
Recruiting
A Study of Azenosertib (ZN-c3) in Patients With Ovarian Cancer
NCT04516447Solid Tumor, Epithelial Ovarian Cancer, Fallopian Tube Cancer, Peritoneal Cancer
K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc
Phase 1
172
Colorado, Massachusetts, Missouri, New York, North Carolina, Rhode Island, Tennessee, Texas
2020-10-26
Recruiting
Abbott Vascular Medical Device Registry
NCT04573660Acute Myocardial Infarction, Restenoses, Coronary, Coronary Artery Lesions, Venous Embolism
Abbott Medical Devices
Observational
3,784
Alabama, Arkansas, California, Illinois, Nebraska, Ohio, Tennessee
2020-10-25
Recruiting
The MIRROR Registry: Minimally Invasive IntRaceRebral HemORrhage Evacuation
NCT04494295Supratentorial Hemorrhage
Integra LifeSciences Corporation
Observational
500
California, Florida, Illinois, Maryland, Michigan, Missouri, New Jersey, New York
2020-10-23
Active, closed
Claudin18.2 CAR-T (CT041) in Patients With Gastric, Pancreatic Cancer, or Other Specified Digestive Cancers
NCT04404595Gastric Cancer, Pancreatic Cancer
CARsgen Therapeutics Co., Ltd.
Phase 1/2
110
California, Florida, Kansas, Michigan, Minnesota, New York, Ohio, Texas
2020-10-23
By invitation
Long-term Follow-up of Subjects with Sickle Cell Disease Treated with Ex Vivo Gene Therapy
NCT04628585Sickle Cell Disease
Genetix Biotherapeutics Inc.
Observational
85
Alabama, California, Georgia, Illinois, Maryland, Minnesota, New Jersey, New York
2020-10-21
By invitation
Post Market Clinical Follow-Up Study for PROFEMUR® Preserve Classic Femoral Stem
NCT04147559Joint Diseases
MicroPort Orthopedics Inc.
Observational
150
Arizona, Colorado
2020-10-21
Recruiting
NEXUS Aortic Arch Clinical Study to Evaluate Safety and Effectiveness
NCT04471909Aortic Dissection, Aortic Aneurysm, Intramural Hematoma, Penetrating Aortic Ulcer
Endospan Ltd.
Not applicable
110
Alabama, California, Colorado, Connecticut, District of Columbia, Florida, Georgia, Illinois
2020-10-20
Active, closed
TTVR Early Feasibility Study
NCT04433065Tricuspid Regurgitation
Medtronic Cardiovascular
Not applicable
150
Alabama, Arizona, California, Connecticut, Georgia, Michigan, Minnesota, Montana
2020-10-20
Active, closed
Study to Continue Treatment With Darolutamide in Patients Who Have Been Participating in Previous Darolutamide Studies Supported by Bayer
NCT04464226Cancer
Bayer
Phase 3
402
Alabama, Arizona, California, Colorado, Florida, Illinois, Kentucky, Maryland
2020-10-20
Active, closed
Tempus Priority Study: A Pan-tumor Observational Study
NCT05179824Breast Cancer, Prostate Cancer, Bladder Cancer, Lung Cancer
Tempus AI
Observational
1,000
Texas
2020-10-19
Active, closed
Study of Cabozantinib in Combination With Atezolizumab Versus Second NHT in Subjects With mCRPC
NCT04446117Metastatic Prostate Cancer, Prostate Adenocarcinoma
Exelixis
Phase 3
575
Arizona, California, Colorado, Connecticut, Florida, Georgia, Kansas, Kentucky
2020-10-19
Active, closed
Study of Durvalumab Versus Placebo in Combination With Definitive Chemoradiation Therapy in Patient With ESCC
NCT04550260Esophageal Squamous Cell Carcinoma
AstraZeneca
Phase 3
640
Georgia, Kentucky, Texas, Virginia, West Virginia
2020-10-19
Active, closed
CHAMPION-AF Clinical Trial
NCT04394546Atrial Fibrillation, Stroke, Bleeding
Boston Scientific Corporation
Not applicable
3,000
Alabama, Arizona, Arkansas, California, Colorado, Connecticut, Delaware, District of Columbia
2020-10-15
Active, closed
Autologous Adipose-derived Stromal Vascular Fraction for Treatment of Knee Osteoarthritis
NCT04440189Osteoarthritis, Knee
GID BIO, Inc.
Phase 3
114
California, Florida, Louisiana, New Jersey, North Carolina, Ohio, Pennsylvania, Texas
2020-10-15
Active, closed
Brain Stimulation & Generalized Anxiety Study
NCT04751864Anxiety, Generalized Anxiety Disorder, Generalized Anxiety
ProofPilot
Phase 4
150
New York
2020-10-15
Active, closed
Myasthenia Gravis Inebilizumab Trial
NCT04524273Myasthenia Gravis
Amgen
Phase 3
238
California, Connecticut, District of Columbia, Florida, Kansas, North Carolina, Ohio, Pennsylvania
2020-10-15
Active, closed
Dual-sided Hypoglossal neRvE stimulAtion for the treatMent of Obstructive Sleep Apnea (DREAM)
NCT03868618Obstructive Sleep Apnea
Nyxoah S.A.
Not applicable
115
Alabama, Florida, Georgia, Indiana, Iowa, Massachusetts, New York, Ohio
2020-10-14
Active, closed
CAN-2409 Plus Prodrug With Standard of Care Immune Checkpoint Inhibitor for Stage III/IV NSCLC
NCT04495153Non Small Cell Lung Cancer
Candel Therapeutics, Inc.
Phase 2
90
Arizona, Connecticut, Illinois, Maryland, Minnesota, New York, Ohio, Pennsylvania
2020-10-13
Active, closed
A Study of Combination Amivantamab and Carboplatin-Pemetrexed Therapy, Compared With Carboplatin-Pemetrexed, in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Characterized by Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions
NCT04538664Carcinoma, Non-Small-Cell Lung
Janssen Research & Development, LLC
Phase 3
308
California, District of Columbia, Florida, Georgia, Michigan, Missouri, New Jersey, New York
2020-10-13
Active, closed
A Phase 2 Study of RTB101 as COVID-19 Post-Exposure Prophylaxis in Older Adults
NCT04584710Covid19
Restorbio Inc.
Phase 2
60
Connecticut, Massachusetts
2020-10-13
Active, closed
A Study Evaluating DS-1055a in Participants With Relapsed or Refractory Locally Advanced or Metastatic Solid Tumors
NCT04419532Solid Tumor, Advanced Cancer, Metastatic Solid Tumor
Daiichi Sankyo
Phase 1
40
New York, Ohio
2020-10-09
Active, closed
A Study Evaluating the Efficacy and Safety of Giredestrant Combined With Palbociclib Compared With Letrozole Combined With Palbociclib in Participants With Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer (persevERA Breast Cancer)
NCT04546009Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer
Hoffmann-La Roche
Phase 3
992
California, Colorado, Florida, Hawaii, Maryland, Massachusetts, Missouri, New Jersey
2020-10-09
Active, closed
Impella ECP Early Feasibility Study
NCT04477603High-risk Percutaneous Coronary Intervention
Abiomed Inc.
Not applicable
100
Massachusetts, Michigan, New Jersey, Ohio
2020-10-09
Active, closed
A Combination of Acalabrutinib With R-CHOP in Subjects With Previously Untreated Non-GCB DLBCL (ACE-LY-312)
NCT04529772Diffuse Large B-Cell Lymphoma
Acerta Pharma BV
Phase 3
611
Arizona, Arkansas, California, Colorado, Connecticut, Florida, Indiana, Iowa
2020-10-08
Active, closed
A Phase I Study of KB301, a Replication-Incompetent, Non-Integrating Vector Expressing Human Type III Collagen (COL3) for the Treatment of Superficial Skin Depressions
NCT04540900Skin Roughness, Wrinkle, Fine Lines, Skin Thickness
Krystal Biotech, Inc.
Phase 1
85
California, Florida
2020-10-07
Active, closed
A Study of DSP107 Alone and in Combination with Atezolizumab for Patients with Advanced Solid Tumors
NCT04440735Advanced Solid Tumor, Non Small Cell Lung Cancer, Colorectal Cancer
Kahr Medical
Phase 1/2
125
California, Colorado, Florida, Indiana, Kansas, Pennsylvania
2020-10-07
Active, closed
Assessment of Efficacy and Safety of Monalizumab Plus Cetuximab Compared to Placebo Plus Cetuximab in Recurrent or Metastatic Head and Neck Cancer
NCT04590963Squamous Cell Carcinoma of the Head and Neck
AstraZeneca
Phase 3
370
Arizona, Illinois, Kansas, Massachusetts, Michigan, Minnesota, Missouri, Nevada
2020-10-02
Active, closed
Study to Evaluate D-1553 in Subjects With Solid Tumors
NCT04585035Solid Tumor, Adult, NSCLC, CRC
InventisBio Co., Ltd
Phase 1/2
180
California, Kentucky, Michigan, New York, Oregon
2020-10-02
Active, closed
Belantamab Mafodotin Plus Pomalidomide and Dexamethasone (Pd) Versus Bortezomib Plus Pd in Relapsed/Refractory Multiple Myeloma
NCT04484623Multiple Myeloma
GlaxoSmithKline
Phase 3
302
Arizona, Florida, Massachusetts, Missouri, Tennessee
2020-10-01
By invitation
Lumbar Interbody Implant Study
NCT04418830Degenerative Disc Disease, Degenerative Spondylolisthesis, Degenerative Scoliosis, Spinal Stenosis
NuVasive
Observational
1,050
California, Connecticut, Florida, Illinois, Michigan, Missouri, North Carolina, Ohio
2020-10-01
Active, closed
A Gene Transfer Study for Late-Onset Pompe Disease (RESOLUTE)
NCT04093349Pompe Disease, Pompe Disease (Late-onset), Glycogen Storage Disease Type 2, Glycogen Storage Disease Type II
Spark Therapeutics, Inc.
Phase 1/2
4
Arizona, California, Georgia, Kansas, Minnesota, Oregon, Pennsylvania, Utah
2020-10-01
Active, closed
Study of LY3410738 Administered to Patients With Advanced Solid Tumors With IDH1 or IDH2 Mutations
NCT04521686Cholangiocarcinoma, Chondrosarcoma, Glioma, Any Solid Tumor
Eli Lilly and Company
Phase 1
200
Arizona, California, Florida, Illinois, Indiana, Maryland, Massachusetts, Minnesota
2020-10-01
Active, closed
Evaluation of a Neurostimulation Device for Insomnia: A Randomized Trial
NCT04627480Insomnia, Insomnia Chronic, Sleep
ProofPilot
Phase 4
200
New York
2020-10-01
Active, closed
Study Comparing Intravenous (IV)/Subcutaneous (SC) Risankizumab to IV/SC Ustekinumab to Assess Change in Crohn's Disease Activity Index (CDAI) in Adult Participants With Moderate to Severe Crohn's Disease (CD)
NCT04524611Crohn's Disease (CD)
AbbVie
Phase 3
527
Arizona, California, Connecticut, Florida, Georgia, Illinois, Kentucky, Louisiana
2020-09-30
Active, closed
A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Crovalimab Versus Eculizumab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Currently Treated With Complement Inhibitors
NCT04432584Paroxysmal Nocturnal Hemoglobinuria
Hoffmann-La Roche
Phase 3
190
North Carolina, Ohio
2020-09-30
By invitation
Post Market Clinical Follow-Up Study- EVOLUTION® Revision CCK
NCT04145401Knee Osteoarthritis
MicroPort Orthopedics Inc.
Observational
45
Colorado
2020-09-30
Active, closed
Less Frequent IV Dosing & Tumor Microenvironment (TME) Study of Nemvaleukin Alfa (ALKS 4230) Monotherapy and in Combination With Pembrolizumab (ARTISTRY-3)
NCT04592653Advanced Solid Tumor
Mural Oncology, Inc
Phase 1/2
78
Michigan, Texas, Utah, Virginia
2020-09-30
Active, closed
A Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib in Locally Advanced or Metastatic Non-Small Cell Lung Cancer
NCT04487080Carcinoma, Non-Small-Cell Lung
Janssen Research & Development, LLC
Phase 3
1,074
Arizona, California, Colorado, Florida, Georgia, Louisiana, Maryland, Michigan
2020-09-30
Recruiting
A Phase 1/2, Open-label, Safety and Dosing Study of Autologous CART Cells (Desmoglein 3 Chimeric Autoantibody Receptor T Cells [DSG3-CAART] or CD19-specific Chimeric Antigen Receptor T Cells [CABA-201]) in Subjects With Active, Pemphigus Vulgaris (RESET-PV)
NCT04422912Pemphigus Vulgaris
Cabaletta Bio
Phase 1/2
40
California, Connecticut, Illinois, Iowa, Massachusetts, New York, North Carolina, Pennsylvania
2020-09-29
By invitation
Follow-up Study of AAV-Mediated Gene Transfer (UX111; Previously Known as ABO-102) for MPS Type IIIA
NCT04360265Mucopolysaccharidosis IIIA, MPS IIIA, Sanfilippo Syndrome, Sanfilippo A
Ultragenyx Pharmaceutical Inc
Phase 3
41
Ohio
2020-09-28
Active, closed
A Study Comparing Savolitinib Plus Osimertinib vs Savolitinib Plus Placebo in Patients With EGFRm+ and MET Amplified Advanced NSCLC
NCT04606771Non-Small Cell Lung Cancer
AstraZeneca
Phase 2
30
California
2020-09-28
Active, closed
Study of AIC100 CAR T Cells in Relapsed/Refractory Thyroid Cancer
NCT04420754Anaplastic Thyroid Cancer, Relapsed/Refractory Poorly Differentiated Thyroid Cancer
AffyImmune Therapeutics, Inc.
Phase 1
70
California, Illinois, New York, Texas
2020-09-28
Recruiting
JuggerStitch Post Market Clinical Follow-up Study
NCT04228367Meniscus Tear, Tibial, Meniscus Lesion
Zimmer Biomet
Not applicable
104
North Carolina, Virginia
2020-09-25
Active, closed
Study of Elafibranor in Patients With Primary Biliary Cholangitis (PBC)
NCT04526665Primary Biliary Cirrhosis
Ipsen
Phase 3
161
Arizona, California, Colorado, Connecticut, Florida, Georgia, Kansas, Massachusetts
2020-09-24
Active, closed
AAV Gene Therapy Study for Subjects with PKU
NCT04480567Phenylketonuria (PKU)
BioMarin Pharmaceutical
Phase 1/2
100
Florida, New Jersey
2020-09-24
Active, closed
A Study of Niraparib in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for the Treatment of Participants With Deleterious Germline or Somatic Homologous Recombination Repair (HRR) Gene-MutatedProstatic Neoplasms (mCSPC)
NCT04497844Prostatic Neoplasms
Janssen Research & Development, LLC
Phase 3
696
Alabama, Arizona, California, Colorado, Connecticut, Florida, Indiana, Louisiana
2020-09-23
Active, closed
Study to Test the Safety and Tolerability of PF-07220060 in Participants With Advance Solid Tumors
NCT04557449Liposarcoma, Prostate Cancer, Breast Neoplasms, Adenocarcinoma of Lung
Pfizer
Phase 2
362
California, Connecticut, Massachusetts, Michigan, Tennessee, Texas
2020-09-23
Active, closed
Open Nipple Sparing Mastectomy (NSM)
NCT04447339Nipple Sparing Mastectomy
Intuitive Surgical
Observational
75
Illinois, Minnesota, New York, Pennsylvania, Texas
2020-09-21
Active, closed
NKX101, Intravenous Allogeneic CAR NK Cells, in Adults With AML or MDS
NCT04623944Relapsed/Refractory AML, AML, Adult, MDS, Refractory Myelodysplastic Syndromes
Nkarta, Inc.
Phase 1
61
Colorado, Florida, Georgia, Illinois, Ohio, Tennessee, Texas
2020-09-21
Active, closed
A Study to Assess the Long-term Safety and Efficacy of a Subcutaneous Formulation of Efgartigimod in Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP, an Autoimmune Disorder That Affects the Peripheral Nerves)
NCT04280718Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
argenx
Phase 2
229
Alabama, Arizona, California, Colorado, Florida, Iowa, Kansas, Kentucky
2020-09-18
Recruiting
A Clinical Study of Intratumoral MVR-T3011 (T3011) Given as a Single Agent and in Combination With Intravenous Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors
NCT04370587Solid Tumor, Melanoma, HNSCC, Sarcoma
ImmVira Pharma Co. Ltd
Phase 1/2
30
Arizona, Massachusetts, Pennsylvania, Texas, Virginia
2020-09-17
Active, closed
A Study of Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma
NCT04557098Hematological Malignancies
Janssen Research & Development, LLC
Phase 2
194
Alabama, California, Georgia, Michigan, New York, North Carolina, Pennsylvania
2020-09-17
Active, closed
Study to Evaluate Loncastuximab Tesirine With Rituximab Versus Immunochemotherapy in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma
NCT04384484Relapsed Diffuse Large B-Cell Lymphoma, Refractory Diffuse Large B-Cell Lymphoma
ADC Therapeutics S.A.
Phase 3
440
California, Florida, Iowa, Kentucky, Nevada, Oregon, South Carolina, Virginia
2020-09-16
Active, closed
PF-07104091 as a Single Agent and in Combination Therapy
NCT04553133Small Cell Lung Cancer, Ovarian Cancer, Breast Cancer
Pfizer
Phase 2
157
Iowa, Kentucky, Massachusetts, New Jersey, New York, Virginia
2020-09-16
Active, closed
Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLC
NCT04140526Non Small Cell Lung Cancer, Advanced Solid Tumor, Metastatic Melanoma, Metastatic Head and Neck Carcinoma
OncoC4, Inc.
Phase 1/2
733
Arkansas, California, Colorado, Connecticut, District of Columbia, Florida, Georgia, Kentucky
2020-09-16
Recruiting
A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome
NCT04462770Dravet Syndrome
Epygenix
Phase 3
150
Alabama, Arkansas, California, Connecticut, Delaware, Florida, Georgia, Illinois
2020-09-15
Active, closed
Tucatinib Plus Trastuzumab and Oxaliplatin-based Chemotherapy or Pembrolizumab-containing Combinations for HER2+ Gastrointestinal Cancers
NCT04430738Colorectal Carcinoma, Gastric Adenocarcinoma, GEJ Adenocarcinoma, Esophageal Adenocarcinoma
Seagen, a wholly owned subsidiary of Pfizer
Phase 2
40
Arizona, Colorado, District of Columbia, Missouri, New Mexico, North Carolina, Ohio, Washington
2020-09-15
Active, closed
Datopotamab Deruxtecan (Dato-DXd) in Combination With Pembrolizumab With or Without Platinum Chemotherapy in Subjects With Advanced or Metastatic Non-Small Cell Lung Cancer (TROPION-Lung02)
NCT04526691Advanced or Metastatic NSCLC
Daiichi Sankyo
Phase 1
145
Arizona, California, District of Columbia, Florida, Maryland, Minnesota, New Mexico, Texas
2020-09-15
Active, closed
A Study of Belzutifan (MK-6482) in Participants With Advanced Renal Cell Carcinoma (MK-6482-013)
NCT04489771Carcinoma, Renal Cell
Merck Sharp & Dohme LLC
Phase 2
154
District of Columbia, Florida, Kentucky, Maryland, Nebraska, New York, Pennsylvania, South Dakota
2020-09-13
Recruiting
Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)
NCT04427384Brain Tumor, Recurrent, Brain Tumor, Brain Tumor, Primary, Brain Tumor - Metastatic
GT Medical Technologies, Inc.
Observational
600
Arizona, Arkansas, California, Colorado, Florida, Georgia, Idaho, Indiana
2020-09-11
Active, closed
Adjuvant Chemotherapy in Patients With Intermediate or High Risk Stage I or Stage IIA Non-squamous Non-Small Cell Lung Cancer: AIM-HIGH (Adjuvant Intervention in Molecular High Risk Patients)
NCT01817192Non-Small Cell Lung Cancer
Razor Genomics
Not applicable
420
California, Florida, Kentucky, Missouri, New Jersey, North Carolina, Oklahoma, Pennsylvania
2020-09-11
Active, closed
A Unique Micro Water Jet Technology Device Versus Standard Debridement in the Treatment of Diabetic Foot
NCT04564443Diabetic Foot Ulcer, Diabetic Foot
Medaxis, LLC
Not applicable
222
California, Florida, Maryland, North Carolina, Ohio, Virginia
2020-09-11
Active, closed
Study Of Venetoclax Tablet With Intravenous or Subcutaneous Azacitidine to Assess Change in Disease Activity In Adult Participants With Newly Diagnosed Higher-Risk Myelodysplastic Syndrome
NCT04401748Myelodysplastic Syndrome (MDS)
AbbVie
Phase 3
531
California, Colorado, Connecticut, Delaware, Florida, Idaho, Illinois, Indiana
2020-09-10
Recruiting
Artesunate Vaginal Inserts for the Treatment of Cervical Intraepithelial Neoplasia (CIN2/3)
NCT04098744CIN 2/3, HPV Infection, Pre-Cancerous Dysplasia, Cervical Dysplasia
Frantz Viral Therapeutics, LLC
Phase 2
78
Florida, Michigan, Ohio, Texas
2020-09-09
Recruiting
Evaluate the Safety and Clinical Activity of HH2853
NCT04390737FL Lymphoma, Epithelioid Sarcoma, Peripheral T Cell Lymphoma, Advanced Solid Tumor
Haihe Biopharma Co., Ltd.
Phase 1/2
254
Arizona, Florida, Minnesota, Texas
2020-09-08
Active, closed
A Phase 1 Trial of ZN-A-1041 Enteric Capsules or Combination in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Advanced Solid Tumors
NCT05593094Advanced Solid Tumors, HER2-positive Breast Cancer
Hoffmann-La Roche
Phase 1/2
210
Arizona, California, Massachusetts, Michigan, North Carolina, Texas
2020-09-03
Active, closed
A Study of Rituximab-Gemcitabine-Dexamethasone-Platinum (R-GDP) With or Without Selinexor in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma
NCT04442022Relapsed/Refractory Diffuse Large B-cell Lymphoma
Karyopharm Therapeutics Inc
Phase 2/3
501
Arizona, California, Kentucky, Maryland, New York, Texas
2020-09-03
Recruiting
ZZ06 in Adult Patients With Advanced Solid Tumor Malignancies
NCT04412616Advanced EGFR Positive Solid Tumor
Changchun Intellicrown Pharmaceutical Co. LTD
Phase 1
60
California, Kansas, New York
2020-09-01
Recruiting
Study of LAM561 Acid in Pediatric Patients With Malignant Glioma and Other Advanced Solid Tumors
NCT04299191High-grade Glioma, Solid Tumor, Unspecified, Child
Laminar Pharmaceuticals
Phase 1/2
28
Arkansas, Florida, New Jersey
2020-09-01
Active, closed
An Open-label, Phase 1/2 Trial of Gene Therapy 4D-310 in Adults With Fabry Disease
NCT04519749Fabry Disease
4D Molecular Therapeutics
Phase 1/2
18
California, Georgia, Pennsylvania, Virginia
2020-09-01
Active, closed
Study of Oral Navitoclax Tablet in Combination With Oral Ruxolitinib Tablet Versus Best Available Therapy to Assess Change in Spleen Volume in Adult Participants With Relapsed/Refractory Myelofibrosis
NCT04468984Myelofibrosis (MF)
AbbVie
Phase 3
330
Arizona, Arkansas, California, Colorado, Georgia, Illinois, Indiana, Louisiana
2020-08-31
Active, closed
A Study of Intravitreal ILUVIEN® Implant as Baseline Therapy in Patients With Early Diabetic Macular Edema (DME)
NCT04469595Diabetic Macular Edema
Alimera Sciences
Phase 4
300
Arizona, California, Colorado, Florida, Georgia, Illinois, Kansas, Louisiana
2020-08-31
Active, closed
Safety and Efficacy Study of CFI-402411 in Subjects With Advanced Solid Malignancies
NCT04521413Advanced Solid Malignancies
Treadwell Therapeutics, Inc
Phase 1/2
170
California, Connecticut, Florida, Michigan, Tennessee, Texas, Virginia
2020-08-31
Recruiting
BOLD-100 in Combination With FOLFOX for the Treatment of Advanced Solid Tumours
NCT04421820Colorectal Cancer, Pancreatic Cancer, Gastric Cancers, Cholangiocarcinoma
Bold Therapeutics, Inc.
Phase 1/2
220
California, Florida
2020-08-28
Active, closed
RGX-314 Gene Therapy Administered in the Suprachoroidal Space for Participants With Neovascular Age-Related Macular Degeneration (nAMD)
NCT04514653Neovascular Age-Related Macular Degeneration (nAMD)
AbbVie
Phase 2
146
Arizona, California, Georgia, Illinois, Maryland, Massachusetts, Nevada, New Mexico
2020-08-25
Active, closed
Oregovomab Plus Chemo in Newly Diagnosed Patients With Advanced Epithelial Ovarian Cancer Following Optimal Debulking Surgery
NCT04498117Carcinoma, Ovarian Epithelial, Ovarian Neoplasms, Ovarian Cancer, Ovarian Serous Adenocarcinoma
CanariaBio Inc.
Phase 3
615
Arizona, California, Colorado, Connecticut, Florida, Georgia, Hawaii, Indiana
2020-08-25
Recruiting
Hydrus® Microstent New Enrollment Post-Approval Study
NCT04553523Primary Open Angle Glaucoma
Alcon Research
Not applicable
545
California, Colorado, Iowa, Kansas, Maryland, Michigan, Minnesota, Missouri
2020-08-25
Active, closed
A Study to Evaluate the Efficacy and Safety of CAEL-101 in Patients With Mayo Stage IIIb AL Amyloidosis (CARES)
NCT04504825AL Amyloidosis
Alexion Pharmaceuticals, Inc.
Phase 3
125
California, Florida, Indiana, Louisiana, Massachusetts, Michigan, Minnesota, Missouri
2020-08-25
Recruiting
Long-term Follow-up of Study Participants Who Received an Allogeneic Chimeric Antigen Receptor T-Cell Product in an Imugene Ltd. Clinical Study
NCT05822427Participants Who Received an Allogeneic Chimeric Antigen Receptor T-Cell Product (PBCAR) in a Precision BioSciences, Inc., Clinical Study
Imugene Limited
Observational
75
California
2020-08-25
Active, closed
Ropeginterferon Alfa-2b (P1101) vs. Anagrelide in Essential Thrombocythemia Patients With Hydroxyurea Resistance or Intolerance
NCT04285086Essential Thrombocythemia
PharmaEssentia
Phase 3
174
Arizona, Missouri, Texas, Utah
2020-08-25
Active, closed
Fisher Wallace Neurostimulation & Depression Study
NCT04541563Major Depressive Disorder
ProofPilot
Not applicable
175
New York
2020-08-24
Active, closed
Brentuximab Vedotin Plus Lenalidomide and Rituximab for the Treatment of Relapsed/Refractory DLBCL
NCT04404283Diffuse Large B-cell Lymphoma
Seagen, a wholly owned subsidiary of Pfizer
Phase 3
239
Alabama, California, Florida, Kansas, Maryland, Michigan, Missouri, Ohio
2020-08-20
Recruiting
Ankle Robotics After Stroke
NCT04594837Foot Drop, Stroke, Hemiparesis
NextStep Robotics Inc.
Not applicable
140
Maryland
2020-08-20
By invitation
Long-Term Follow Up Study of Subjects Previously Administered HMI 102
NCT04348708Phenylketonuria, PAH Deficiency
Homology Medicines, Inc
Observational
21
Massachusetts, New York
2020-08-19
Active, closed
Cerliponase Alfa Observational Study in the US
NCT04476862Late-Infantile Neuronal Ceroid Lipofuscinosis Type 2
BioMarin Pharmaceutical
Observational
35
Arkansas, California, Colorado, District of Columbia, Florida, Georgia, Illinois, Massachusetts
2020-08-19
Recruiting
A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS)
NCT04419649Myelodysplastic Syndromes, Cytopenia
Takeda
Phase 2
160
Arkansas, California, Florida, Maryland, Michigan, New Jersey, New York, Pennsylvania
2020-08-19
Active, closed
LIFE-BTK Randomized Controlled Trial
NCT04227899Critical Limb Ischemia (CLI)
Abbott Medical Devices
Not applicable
261
Arizona, Arkansas, California, Colorado, Connecticut, Florida, Georgia, Illinois
2020-08-18
Active, closed
A Phase 2 Study of T-DXd in Patients With Selected HER2 Expressing Tumors
NCT04482309Part 1: Bladder, Biliary Tract, Cervical, Endometrial, Ovarian, Pancreatic Cancer, Rare Tumors, Any Tumor Type Excluding Breast, Gastric, Colorectal Cancer, Part 2: HER2 Expressing/Amplified Solid Tumors Excluding Breast, Gastric, Colorectal Cancer
AstraZeneca
Phase 2
477
California, Illinois, Indiana, Massachusetts, New Jersey, New York, North Carolina, Texas
2020-08-18
Active, closed
Study to Evaluate the Efficacy and Safety of PF-07055480 / Giroctocogene Fitelparvovec Gene Therapy in Moderately Severe to Severe Hemophilia A Adults
NCT04370054Hemophilia A
Pfizer
Phase 3
77
California, Washington
2020-08-18
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Priya Life Science (2026). Clinical trial register: industry-sponsored studies with a US investigative site. Derived from ClinicalTrials.gov. Retrieved 22 September 2026. https://priyalifescience.com/clinical-trials-usa?page=81

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Listing here is informational and not medical advice; eligibility is determined by each study team. Compare pay for the teams running these studies in the US Pharma Salary Guide, see who's behind them in the US Company Directory, or track approvals on the FDA Approvals Tracker. For Irish, UK and EU sites, see the Ireland, UK and EU registers.