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Trackers› Clinical trials› USA
Clinical trial register · United States · industry-sponsored

Industry-sponsored studies with a US investigative site

Every industry-sponsored study on the ClinicalTrials.gov registry that lists a US site and is open, about to open, active-but-closed, or enrolling by invitation. This deliberately excludes academic and other non-industry sponsors โ€” the full US registry across all sponsors runs to over 22,000 recruiting studies alone.

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Source: ClinicalTrials.gov. Complete coverage of the industry-sponsored slice โ€” all 9112 matching records are in this view (non-industry sponsors are out of scope by design, not truncated). Synced 23 Sep 2026, 03:16 UTC
9112
Studies in scope
industry-sponsored, all four open statuses
4950
Recruiting now
open to new participants
2202
Lead sponsors
across recruiting studies
Top states
California 5295 Florida 4397 Illinois 2479 Georgia 2346 Arizona 2231
Narrow the register
Recruitment status
Phase
Lead sponsor
AstraZeneca299 Novartis Pharmaceuticals202 Eli Lilly and Company190 Merck Sharp & Dohme LLC183 AbbVie172
State
California5295 Florida4397 Illinois2479 Georgia2346 Arizona2231
All 51 states
Target enrolment
to
9112 of 9112 studies
Download
Status
Study
Lead sponsor
Phase
Enrol
US states
Start
Active, closed
Study to Evaluate the Efficacy and Safety of PF-07055480 / Giroctocogene Fitelparvovec Gene Therapy in Moderately Severe to Severe Hemophilia A Adults
NCT04370054Hemophilia A
Pfizer
Phase 3
77
California, Washington
2020-08-18
Active, closed
LIFE-BTK Randomized Controlled Trial
NCT04227899Critical Limb Ischemia (CLI)
Abbott Medical Devices
Not applicable
261
Arizona, Arkansas, California, Colorado, Connecticut, Florida, Georgia, Illinois
2020-08-18
Recruiting
A Trial of AMXI-5001 for Treatment in Patients With Advanced Malignancies
NCT04503265Advanced Malignant Neoplasm, Breast Cancer, Ovarian Cancer, Homologous Recombination Deficiency
AtlasMedx, Incorporated
Phase 1/2
122
California, Maryland, Tennessee, Texas
2020-08-12
Active, closed
A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab + Lenalidomide (+Len), and the Safety, Tolerability, and Pharmacokinetics of SC Versus IV Mosunetuzumab + Len in Participants With Follicular Lymphoma
NCT04246086Follicular Lymphoma
Hoffmann-La Roche
Phase 1/2
237
California, Florida, Kentucky, Louisiana, Michigan, North Carolina, Ohio, Rhode Island
2020-08-12
Active, closed
Study Of Oral Elagolix Tablets In Combination With Combined Oral Contraceptive Capsules/Tablets To Assess Dysmenorrhea Response In Adult Female Participants With Endometriosis And Associated Moderate To Severe Pain
NCT04333576Endometriosis
AbbVie
Phase 3
800
Alabama, Arizona, Arkansas, California, Colorado, Delaware, District of Columbia, Florida
2020-08-10
Active, closed
A Study to Evaluate the Efficacy and Safety of Obinutuzumab in Participants With ISN/RPS 2003 Class III or IV Lupus Nephritis
NCT04221477Lupus Nephritis
Hoffmann-La Roche
Phase 3
271
Alabama, California, Colorado, Connecticut, Florida, Georgia, New York, Ohio
2020-08-10
Active, closed
A Safety Study of SEA-CD70 in Patients With Myeloid Malignancies
NCT04227847Myelodysplastic Syndrome, Acute Myeloid Leukemia
Seagen, a wholly owned subsidiary of Pfizer
Phase 1
170
Alabama, California, Colorado, Kansas, Kentucky, Massachusetts, Michigan, Missouri
2020-08-07
Recruiting
A Study to Evaluate the Safety, Tolerability, and Efficacy of MORAb-202 (Herein Referred to as Farletuzumab Ecteribulin), a Folate Receptor Alpha (FRฮฑ)-Targeting Antibody-drug Conjugate (ADC) in Participants With Selected Tumor Types
NCT04300556Solid Tumor
Eisai Inc.
Phase 1/2
182
Arizona, Arkansas, California, Florida, Georgia, Illinois, Kentucky, Maryland
2020-08-06
Recruiting
Non-Invasive Quantification of Liver Health in NASH (N-QUAN)
NCT04054310NASH - Nonalcoholic Steatohepatitis
Perspectum
Not applicable
225
Arizona, Illinois, Indiana, New York, Texas, Virginia
2020-08-05
Active, closed
Open-label Extension of the HOPE-2 Trial
NCT04428476Duchenne Muscular Dystrophy
Capricor Inc.
Phase 2
13
California, Colorado, Missouri, Ohio, Wisconsin
2020-08-05
Active, closed
A Study to Evaluate MEDI5752 and Axitinib in Subjects With Advanced Renal Cell Carcinoma
NCT04522323Advanced Renal Cell Carcinoma
MedImmune LLC
Phase 1
67
District of Columbia, Florida, Missouri, New York, Ohio, Pennsylvania, Tennessee
2020-08-05
Active, closed
Roll Over StudY for Patients Who Have Completed a Previous Oncology Study With Olaparib
NCT04421963Ovarian Cancer, Breast Cancer
AstraZeneca
Phase 3
185
Florida, Maryland, Michigan, Minnesota, New Jersey, New York, Pennsylvania, Rhode Island
2020-08-04
Active, closed
Rollover Study to Provide Continued Treatment for Participants With B-Cell Malignancies Previously Enrolled in Studies of Parsaclisib (INCB050465)
NCT04509700B-Cell Malignancies
Incyte Corporation
Phase 2
112
Alabama, Arizona, California, Colorado, Illinois, Kansas, Maryland, Massachusetts
2020-08-03
Recruiting
Th-1 Dendritic Cell Immunotherapy Plus Standard Chemotherapy for Pancreatic Adenocarcinoma
NCT04157127Pancreatic Adenocarcinoma, Pancreatic Cancer, Pancreatic Adenosquamous Carcinoma
Diakonos Oncology Corporation
Phase 1
18
Texas
2020-08-03
Active, closed
Artoss Prospective Spine Registry Outcomes
NCT04439032Spinal Fusion
Artoss Inc.
Observational
330
Arizona, California, Connecticut, Maryland, Mississippi
2020-08-03
Active, closed
Personalized Therapy Study - Intrinsic Antitachycardia Pacing Post-Approval Study (iATP PAS)
NCT04496518Ventricular Tachycardia
Medtronic
Observational
2,200
Arizona, Arkansas, California, Colorado, Connecticut, Florida, Indiana, Iowa
2020-08-01
Recruiting
Patisiran-Lipid Nanoparticle (LNP) Pregnancy Surveillance Program
NCT05040373Hereditary Transthyretin-mediated (hATTR) Amyloidosis, Polyneuropathy
Alnylam Pharmaceuticals
Observational
10
Iowa
2020-08-01
Active, closed
Personalized Therapy Study - HFRS (TriageHF) Post Approval Study
NCT04489225Heart Failure
Medtronic
Observational
2,200
Arizona, Arkansas, California, Colorado, Connecticut, Florida, Indiana, Iowa
2020-08-01
Active, closed
A Study to Test Different Doses of Obrixtamig in Patients With Small Cell Lung Cancer and Other Neuroendocrine Tumours That Are Positive for DLL3
NCT04429087Small Cell Lung Carcinoma and Other Neuroendocrine Neoplasms Expressing DLL3
Boehringer Ingelheim
Phase 1
306
Georgia, Maryland, Missouri, Pennsylvania
2020-07-29
Active, closed
A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-6036 Alone or in Combination in Participants With Advanced or Metastatic Solid Tumors With a KRAS G12C Mutation
NCT04449874Non-Small Cell Lung Cancer, Colorectal Cancer, Advanced Solid Tumors
Genentech, Inc.
Phase 1
498
California, Connecticut, Florida, Massachusetts, New York, Oklahoma, Pennsylvania
2020-07-29
Active, closed
Safety and Effectiveness Study of OR3Oโ„ข Dual Mobility System in THA
NCT04325022Advanced Degeneration of the Hip Joint, Revision of the Hip Joint
Smith & Nephew, Inc.
Observational
177
Kentucky, Nebraska, New York, North Carolina, Texas
2020-07-27
Active, closed
Study of Trastuzumab Deruxtecan (T-DXd) vs Investigator's Choice Chemotherapy in HER2-low, Hormone Receptor Positive, Metastatic Breast Cancer
NCT04494425Advanced or Metastatic Breast Cancer
AstraZeneca
Phase 3
866
Arizona, Arkansas, California, Colorado, District of Columbia, Florida, Kansas, Kentucky
2020-07-24
Active, closed
Combination Immunotherapy Plus Standard-of-Care Chemotherapy Versus Standard-of-Care Chemotherapy for the Treatment of Locally Advanced or Metastatic Pancreatic Cancer
NCT04390399Pancreatic Cancer
ImmunityBio, Inc.
Phase 2
328
California, New Jersey, South Dakota
2020-07-21
Active, closed
MitraClip REPAIR MR Study
NCT04198870Mitral Valve Regurgitation
Abbott Medical Devices
Not applicable
500
Alabama, Arizona, California, Colorado, Connecticut, Florida, Georgia, Illinois
2020-07-21
Active, closed
A Phase III Study to Evaluate the Efficacy and Safety of Benralizumab in Patients With Hypereosinophilic Syndrome (HES)
NCT04191304Hypereosinophilic Syndrome
AstraZeneca
Phase 3
134
California, Georgia, Maryland, Michigan, North Carolina, Ohio, Utah
2020-07-20
Active, closed
Study BT8009-100 in Subjects With Nectin-4 Expressing Advanced Malignancies
NCT04561362Urinary Bladder Neoplasm, Triple Negative Breast Neoplasms, Hormone Receptor Positive, HER2-negative Neoplasms, Hormone Receptor Positive, HER2-low Neoplasms
BicycleTx Limited
Phase 1/2
329
Colorado, Florida, New York, Ohio, Pennsylvania, Tennessee, Texas
2020-07-17
Active, closed
Study of Alpelisib (BYL719) in Combination With Trastuzumab and Pertuzumab as Maintenance Therapy in Patients With HER2-positive Advanced Breast Cancer With a PIK3CA Mutation
NCT04208178Advanced HER2+Breast Cancer
Novartis Pharmaceuticals
Phase 3
19
Arkansas, California
2020-07-16
Active, closed
A Study of Tividenofusp Alfa (DNL310) in Pediatric Participants With Hunter Syndrome
NCT04251026Mucopolysaccharidosis II
Denali Therapeutics Inc.
Phase 1/2
47
California, Illinois, North Carolina, Pennsylvania
2020-07-16
Active, closed
Gene Therapy for Fanconi Anemia, Complementation Group A
NCT04248439Fanconi Anemia Complementation Group A
Rocket Pharmaceuticals Inc.
Phase 2
5
California, Minnesota
2020-07-15
Recruiting
An Early Feasibility Study of the HighLife 28mm Trans-Septal Transcatheter Mitral Valve Replacement System
NCT04029337Mitral Regurgitation
HighLife SAS
Not applicable
30
Arizona, California, Georgia, Massachusetts, Minnesota, New York, Pennsylvania, South Carolina
2020-07-14
Active, closed
TTX-080 HLA-G Antagonist in Subjects With Advanced Cancers
NCT04485013Cancer
Tizona Therapeutics, Inc
Phase 1
240
Arizona, California, Colorado, Connecticut, Delaware, District of Columbia, Florida, Illinois
2020-07-14
Active, closed
A Study to Evaluate the Efficacy and Safety of JCAR017 in Adult Subjects With Relapsed or Refractory Indolent B-cell Non-Hodgkin Lymphoma (NHL)
NCT04245839Lymphoma, Non-Hodgkin
Celgene
Phase 2
276
California, Colorado, Connecticut, Illinois, Iowa, Kansas, Maryland, Massachusetts
2020-07-14
Active, closed
Linerixibat Long-term Safety, and Tolerability Study
NCT04167358Cholestasis
GlaxoSmithKline
Phase 3
242
California, Florida, Michigan, New York, North Carolina, Pennsylvania, Texas, Washington
2020-07-14
Active, closed
Trial of Dichloroacetate in Pyruvate Dehydrogenase Complex Deficiency:
NCT02616484Pyruvate Dehydrogenase Complex Deficiency
Saol Therapeutics Inc
Phase 3
34
California, District of Columbia, Florida, Ohio, Pennsylvania, Texas, Utah, Washington
2020-07-14
Active, closed
AHEAD 3-45 Study: A Study to Evaluate Efficacy and Safety of Treatment With Lecanemab in Participants With Preclinical Alzheimer's Disease and Elevated Amyloid and Also in Participants With Early Preclinical Alzheimer's Disease and Intermediate Amyloid
NCT04468659Preclinical Alzheimer's Disease, Early Preclinical Alzheimer's Disease
Eisai Inc.
Phase 3
1,400
Alabama, Arizona, California, Connecticut, District of Columbia, Florida, Georgia, Illinois
2020-07-14
Active, closed
Capivasertib+Abiraterone as Treatment for Patients With Metastatic Hormone-sensitive Prostate Cancer and PTEN Deficiency
NCT04493853Hormone-Sensitive Prostate Cancer
AstraZeneca
Phase 3
1,012
Arizona, California, Colorado, Connecticut, Florida, Illinois, Maryland, Michigan
2020-07-13
Active, closed
A Study to Compare Safety and Efficacy of High Doses of Eteplirsen in Participants With Duchenne Muscular Dystrophy (DMD) (MIS51ON)
NCT03992430Muscular Dystrophy, Duchenne
Sarepta Therapeutics, Inc.
Phase 3
160
Alabama, Florida, Georgia
2020-07-13
Recruiting
Follow-up With Preimplantation Genetic Testing Patients
NCT04477863Infertility, Genetic Disease, IVF
Genomic Prediction Inc.
Observational
10,000
New Jersey
2020-07-11
Active, closed
A Long-term Study of ADYNOVI/ADYNOVATE in Participants With Haemophilia A
NCT04158934Hemophilia A
Baxalta now part of Shire
Observational
207
Florida
2020-07-09
Recruiting
Mesenchymal Stem Cells for the Treatment of Various Chronic and Acute Conditions
NCT04684602Autoimmune Diseases, Cardiovascular Disorders, Diabetes Complications, Integumentary Disease
Thomas Advanced Medical LLC
Phase 1/2
5,000
California
2020-07-09
Active, closed
RejuvenAirยฎ System Trial for COPD With Chronic Bronchitis
NCT03893370Chronic Bronchitis
CSA Medical, Inc.
Not applicable
210
Arizona, California, Florida, Illinois, Louisiana, Maryland, Massachusetts, Michigan
2020-07-09
Active, closed
RETHINK REFLUX Registry
NCT04253392Gastroesophageal Reflux
Ethicon Endo-Surgery
Observational
500
Alabama, Arizona, California, Colorado, Florida, Illinois, Kentucky, Michigan
2020-07-08
Active, closed
Evaluation of Safety and Effectiveness of Stryker Surpass Evolveโ„ข Flow Diverter System
NCT04195568Aneurysm, Intracranial
Stryker Neurovascular
Not applicable
248
Arizona, California, Florida, Illinois, Indiana, Iowa, Kansas, Kentucky
2020-07-07
Active, closed
Amplatzer Amulet LAAO vs. NOAC
NCT04226547Atrial Fibrillation, Stroke, Bleeding
Abbott Medical Devices
Not applicable
2,650
Alabama, Arizona, Arkansas, California, Colorado, District of Columbia, Florida, Georgia
2020-07-07
By invitation
Cervical Interbody Implant Study
NCT04689854Degenerative Disc Disease, Cervical Spinal Instability
NuVasive
Observational
150
California, Connecticut, Massachusetts, Missouri, North Carolina, Ohio, Virginia
2020-07-07
Active, closed
SELUTION SLRโ„ข 014 In-stent Restenosis
NCT04280029Coronary Restenosis
M.A. Med Alliance S.A.
Not applicable
418
California, Colorado, District of Columbia, Florida, Georgia, Indiana, Kansas, Maryland
2020-07-06
Active, closed
Study of Pembrolizumab With Concurrent Chemoradiation Therapy Followed by Pembrolizumab With or Without Olaparib in Stage III Non-Small Cell Lung Cancer (NSCLC) (MK-7339-012/KEYLYNK-012)
NCT04380636Lung Neoplasms, Carcinoma, Non-Small-Cell Lung
Merck Sharp & Dohme LLC
Phase 3
870
Alabama, Arkansas, California, Florida, Indiana, Kentucky, Massachusetts, Michigan
2020-07-06
Active, closed
Efficacy and Safety of Tildrakizumab Compared to Placebo in Anti-TNF naรฏve Subjects With Active Psoriatic Arthritis II (INSPIRE 2)
NCT04314531Active Psoriatic Arthritis
Sun Pharmaceutical Industries Limited
Phase 3
296
California, Florida, Missouri, Nebraska, South Carolina, Texas, Washington
2020-07-01
Active, closed
A Phase 1-2 Study of ST101 in Patients With Advanced Solid Tumors
NCT04478279Glioblastoma, Melanoma Stage IV, Breast Cancer, Prostate Cancer
Sapience Therapeutics
Phase 1/2
125
California, Colorado, Illinois, Michigan, New York, North Carolina, Tennessee
2020-07-01
Active, closed
Bilateral Treatment of Medication Refractory Essential Tremor
NCT04112381Essential Tremor
InSightec
Not applicable
51
California, Maryland, New York, Ohio, Pennsylvania, Virginia, West Virginia
2020-06-30
Active, closed
Outcome Study Assessing a 75 Milligrams (mg) Dose of Macitentan in Patients With Pulmonary Arterial Hypertension
NCT04273945Pulmonary Arterial Hypertension
Actelion
Phase 3
935
Arizona, California, Colorado, Florida, Georgia, Illinois, Indiana, Iowa
2020-06-30
Recruiting
Study of SX-682 Alone and in Combination With Oral or Intravenous Decitabine in Subjects With Myelodysplastic Syndrome
NCT04245397Myelodysplastic Syndromes
Syntrix Biosystems, Inc.
Phase 1
151
Florida, Georgia, Maryland, New York
2020-06-30
Recruiting
A Study of BI-1206 in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors
NCT04219254Solid Tumor, Adult
BioInvent International AB
Phase 1/2
197
California, Colorado, Minnesota, Oklahoma, Texas
2020-06-29
Active, closed
Chimney EndoVascular Aneurysm Sealing Of New Expanded Indication
NCT042525731 Paravisceral Abdominal Aortic Aneurysm, 2 Juxtarenal Abdominal Aortic Aneurysm, 3 Pararenal Abdominal Aortic Aneurysm, 4 Complex Abdominal Aortic Aneurysms
Endologix
Not applicable
13
Alabama, District of Columbia, Georgia, Indiana, Missouri, New Jersey, New York, Oregon
2020-06-29
Recruiting
An Open-Label Study of INV-1120 as a Single Agent and in Combination With Pembrolizumab in Adult Patients With Advanced Solid Tumors
NCT04443088Cancer, Solid Tumor, Adult, Cancer Metastatic, Solid Carcinoma
Shenzhen Ionova Life Sciences Co., Ltd.
Phase 1
78
Indiana, Texas
2020-06-26
Active, closed
Study of the Safety and Effectiveness of GSK6097608 in Participants With Advanced Solid Tumors
NCT04446351Neoplasms
GlaxoSmithKline
Phase 1
107
California, Massachusetts, Texas
2020-06-25
Recruiting
Efficacy and Safety of the CG-100 Intraluminal Bypass Device
NCT04184973Rectal Cancer, Rectal Tumor, Rectal/Anal
Colospan Ltd.
Not applicable
250
California, Colorado, Michigan, Rhode Island, Utah
2020-06-23
Active, closed
A Long-term Extension Study of Mirikizumab (LY3074828) in Participants With Crohn's Disease
NCT04232553Crohn's Disease
Eli Lilly and Company
Phase 3
996
Alabama, Arizona, California, Connecticut, Florida, Georgia, Idaho, Indiana
2020-06-22
Active, closed
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)
NCT04437511Alzheimer Disease
Eli Lilly and Company
Phase 3
1,736
Arizona, Arkansas, California, Colorado, Connecticut, District of Columbia, Florida, Georgia
2020-06-19
Active, closed
Efficacy of EsoGuard Assay on Esophageal Surface Cells Collected With EsoCheck vs EGD for the Diagnosis of BE or EAC
NCT04295811Barrett Esophagus, Esophageal Adenocarcinoma, Barretts Esophagus With Dysplasia, Barrett's Esophagus Without Dysplasia
Lucid Diagnostics, Inc.
Not applicable
784
Colorado, District of Columbia, Florida, Illinois, Louisiana, Maryland, Massachusetts, Michigan
2020-06-18
Active, closed
Episealerยฎ Knee System IDE Clinical Study
NCT04000659Degenerative Lesion of Articular Cartilage of Knee
Episurf Medical Inc.
Not applicable
13
Arizona, California, Louisiana, New Jersey, New York, Ohio, Tennessee, Texas
2020-06-18
Active, closed
Isatuximab in Combination With Lenalidomide and Dexamethasone in High-risk Smoldering Multiple Myeloma
NCT04270409Plasma Cell Myeloma
Sanofi
Phase 3
337
California, Colorado, Florida, Massachusetts, North Carolina, Tennessee, Texas
2020-06-16
Active, closed
Protection Against Emboli During Carotid Artery Stenting Using the Neuroguard IEP System
NCT04201132Carotid Artery Stenosis, Carotid Artery Diseases, Carotid Stenosis
Contego Medical, Inc.
Not applicable
305
Alabama, California, District of Columbia, Florida, Iowa, Kentucky, Louisiana, Maryland
2020-06-12
Active, closed
A Study Comparing JNJ-68284528, a CAR-T Therapy Directed Against B-cell Maturation Antigen (BCMA), Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) or Daratumumab, Pomalidomide and Dexamethasone (DPd) in Participants With Relapsed and Lenalidomide-Refractory Multiple Myeloma
NCT04181827Multiple Myeloma
Janssen Research & Development, LLC
Phase 3
419
Alabama, Arizona, California, Colorado, Connecticut, Florida, Iowa, Kansas
2020-06-12
Active, closed
A Study of LY3295668 Erbumine in Participants With Relapsed/Refractory Neuroblastoma
NCT04106219Neuroblastoma
Eli Lilly and Company
Phase 1
71
California, Colorado, Illinois, Massachusetts, Ohio, Pennsylvania, Texas
2020-06-11
Active, closed
A Study to Assess the Efficacy, Safety, Pharmacodynamics, and Pharmacokinetics of Tazemetostat in Combination With Lenalidomide Plus Rituximab Versus Placebo in Combination With Lenalidomide Plus Rituximab in Adult Patients at Least 18 Years of Age With Relapsed/Refractory Follicular Lymphoma.
NCT04224493Relapsed/Refractory Follicular Lymphoma, Follicular Lymphoma, Refractory Follicular Lymphoma
Epizyme, Inc.
Phase 3
599
Alabama, Arizona, California, Colorado, Florida, Illinois, Michigan, Minnesota
2020-06-11
Active, closed
A Study to Assess Overall Response Rate by Inducing an Inflammatory Phenotype in Metastatic BReast cAnCEr With the Oncolytic Reovirus PeLareorEp in CombinaTion With Anti-PD-L1 Avelumab and Paclitaxel - BRACELET-1 Study
NCT04215146Breast Cancer Metastatic
Oncolytics Biotech
Phase 2
48
Florida, Illinois, Indiana, Louisiana, Missouri, New Jersey, New York, Ohio
2020-06-10
Active, closed
4D-125 in Patients With X-Linked Retinitis Pigmentosa (XLRP)
NCT04517149X-Linked Retinitis Pigmentosa
4D Molecular Therapeutics
Phase 1/2
21
Colorado, Florida, Michigan, New York, North Carolina, Oregon, Texas, Utah
2020-06-09
Active, closed
A Study of FCX-007 for Recessive Dystrophic Epidermolysis Bullosa
NCT04213261Recessive Dystrophic Epidermolysis Bullosa
Castle Creek Biosciences, LLC.
Phase 3
6
California, Colorado, Florida, Minnesota, Texas
2020-06-09
Active, closed
Sub-study of Belantamab Mafodotin (GSK2857916) in Combination With Nirogacestat in Participants With RRMM
NCT07084896Multiple Myeloma
GlaxoSmithKline
Phase 1/2
106
Georgia, Massachusetts, Michigan, Wisconsin
2020-06-08
Recruiting
A Study of Sigvotatug Vedotin in Advanced Solid Tumors
NCT04389632Carcinoma, Non-Small Cell Lung, Squamous Cell Carcinoma of Head and Neck, HER2 Negative Breast Neoplasms, Esophageal Squamous Cell Carcinoma
Seagen, a wholly owned subsidiary of Pfizer
Phase 1
1,006
Alaska, Arkansas, California, Florida, Illinois, Indiana, Kansas, Massachusetts
2020-06-08
Active, closed
A Study of CD19 Targeted CAR T Cell Therapy in Adult Patients With Relapsed or Refractory B Cell Acute Lymphoblastic Leukaemia (ALL)
NCT04404660Relapsed or Refractory B Cell Acute Lymphoblastic Leukemia
Autolus Limited
Phase 1/2
153
California, Colorado, Florida, Georgia, Illinois, Kansas, Maryland, Massachusetts
2020-06-03
Active, closed
Ph1b/2 Study of the Safety and Efficacy of T-DXd Combinations in Advanced HER2-expressing Gastric Cancer (DESTINY-Gastric03)
NCT04379596Gastric Cancer
AstraZeneca
Phase 2
452
Maryland, Massachusetts, New York, Texas
2020-06-03
Active, closed
Dose Escalation Study of Intravitreal 4D-110 in Patients With Choroideremia
NCT04483440Choroideremia
4D Molecular Therapeutics
Phase 1
13
Texas, Utah
2020-06-02
By invitation
Coronary CT Angiography Evaluation for Clinical Outcomes: An International Multicenter Registry
NCT04279496Coronary Artery Disease
Cleerly, Inc.
Observational
15,000
Virginia
2020-06-01
Recruiting
Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors
NCT04429542Head and Neck Squamous Cell Carcinoma, Squamous Cell Carcinoma of Anal Canal, Colorectal Cancer, Squamous Cell Carcinoma of the Lung
Bicara Therapeutics
Phase 1
292
California, Florida, Massachusetts, New York, North Carolina, Ohio, Pennsylvania, Rhode Island
2020-06-01
Active, closed
Post-approval Registry Study to Evaluate the Continued Safety and Probable Benefit of the MID-C System for 5 Years Post-Implantation in Adolescent Idiopathic Scoliosis (AIS)
NCT04296903Adolescent Idiopathic Scoliosis
Apifix
Not applicable
201
California, Florida, Georgia, Indiana, Kansas, Minnesota, Mississippi, Missouri
2020-05-31
Active, closed
Evaluation of MN-166 (Ibudilast) for 12 Months Followed by an Open-label Extension for 6 Months in Patients With ALS
NCT04057898Amyotrophic Lateral Sclerosis
MediciNova
Phase 2/3
234
California, Florida, Georgia, Indiana, Maryland, Minnesota, New York, North Carolina
2020-05-28
Active, closed
A Trial to Evaluate Safety and Tolerability of TST001 in Advanced or Metastatic Solid Tumors
NCT04396821Advanced Cancer, Gastric Cancer, Gastroesophageal-junction Cancer, Pancreatic Cancer
Transcenta Therapeutics (Hangzhou) Co., Ltd.
Phase 1/2
150
Arizona, Connecticut, Florida, Georgia, Kansas, Missouri, New York, North Carolina
2020-05-28
Not yet open
SM-1 vs. an Active Comparator in A Model of Transient Insomnia
NCT04396327Transient Insomnia
Sequential Medicine Ltd
Phase 2
14
New York
2020-05-27
Active, closed
The JenaValve ALIGN-AR Pivotal Trial
NCT04415047Aortic Regurgitation, Aortic Valve Insufficiency, Aortic Insufficiency, Aortic Valve Disease
JenaValve Technology, Inc.
Not applicable
180
Arizona, California, District of Columbia, Florida, Georgia, Illinois, Maryland, Michigan
2020-05-22
Recruiting
A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)
NCT04256317Myelodysplastic Syndromes, Acute Myeloid Leukemia, Myelodysplastic Syndrome/Neoplasm, Chronic Myelomonocytic Leukemia
Taiho Oncology, Inc.
Phase 2/3
316
California, Connecticut, Florida, Georgia, Massachusetts, New Jersey, New York, North Carolina
2020-05-21
Active, closed
Safety and Efficacy of ALLO-501A Anti-CD19 Allogeneic CAR T Cells in Adults With Relapsed/Refractory Large B Cell Lymphoma, Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma (ALPHA2)
NCT04416984Relapsed or Refractory Large B Cell Lymphoma, Relapsed or Refractory Chronic Lymphocytic Leukemia, Relapsed or Refractory Small Lymphocytic Lymphoma
Allogene Therapeutics
Phase 1/2
160
Arizona, California, Colorado, Connecticut, Florida, Georgia, Illinois, Kentucky
2020-05-21
Active, closed
Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Chemoradiotherapy (CRT) Versus CRT Alone in Muscle-invasive Bladder Cancer (MIBC) (MK-3475-992/KEYNOTE-992)
NCT04241185Urinary Bladder Neoplasms
Merck Sharp & Dohme LLC
Phase 3
520
District of Columbia, Florida, Kentucky, Maryland, Missouri, New Jersey, New York, Ohio
2020-05-19
Active, closed
Study to Investigate the Efficacy and Safety of RP1 in Adult Patients With Organ Transplants and Advanced Skin Malignancies
NCT04349436Merkel Cell Carcinoma, Basal Cell Carcinoma, Locally Advanced Cutaneous Squamous Cell Carcinoma, Cancer
Replimune, Inc.
Phase 1/2
69
Arizona, California, Colorado, Florida, Massachusetts, Minnesota, Missouri, New York
2020-05-15
Active, closed
Evaluation of Efficacy and Safety of Belantamab Mafodotin, Bortezomib and Dexamethasone Versus Daratumumab, Bortezomib and Dexamethasone in Participants With Relapsed/Refractory Multiple Myeloma
NCT04246047Multiple Myeloma
GlaxoSmithKline
Phase 3
494
Arizona, Colorado, Kansas, Ohio, Texas
2020-05-07
Active, closed
2019-06 TRISCEND Study
NCT04221490Tricuspid Valve Regurgitation, Heart Valve Diseases, Cardiovascular Diseases
Edwards Lifesciences
Not applicable
228
California, Georgia, Illinois, Massachusetts, Michigan, New York, Oregon, Pennsylvania
2020-05-06
Active, closed
Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer
NCT04269200Endometrial Neoplasms
AstraZeneca
Phase 3
805
Arizona, California, Colorado, Florida, Georgia, Hawaii, Illinois, Indiana
2020-05-05
Active, closed
Long-Term Prospective Registry in Prostate Cancer Patients From Diverse Urology Practice Settings Following Prolarisยฎ Testing
NCT04404894Prostate Cancer
Myriad Genetic Laboratories, Inc.
Observational
500
Alabama, California, Florida, Illinois, Maryland, Tennessee
2020-04-30
Active, closed
Registry of Sarcoma Patients Treated With Permanently Implantable LDR CivaSheetยฎ
NCT04033081Sarcoma
CivaTech Oncology
Phase 4
100
Pennsylvania
2020-04-30
Active, closed
Phase 2 Trial of Voyager V1 in Combination With Cemiplimab in Cancer Patients
NCT04291105Melanoma, Head and Neck Squamous Cell Carcinoma, Colo-rectal Cancer
Vyriad, Inc.
Phase 2
87
California, Connecticut, Florida, Louisiana, Minnesota, Montana, New York, Ohio
2020-04-24
Active, closed
A Study to Investigate Efficacy and Safety With Oral AZD9833 Compared With Intramuscular Fulvestrant in Post-menopausal Women at Least 18 Years of Age With Advanced ER-positive HER2 Negative Breast Cancer
NCT04214288Advanced ER-Positive HER2-Negative Breast Cancer
AstraZeneca
Phase 2
240
Alabama, California, Florida, Nebraska, Ohio, Tennessee, Wisconsin
2020-04-22
Active, closed
Capivasertib+Fulvestrant vs Placebo+Fulvestrant as Treatment for Locally Advanced (Inoperable) or Metastatic HR+/HER2- Breast Cancer
NCT04305496Locally Advanced (Inoperable) or Metastatic Breast Cancer
AstraZeneca
Phase 3
818
Arizona, California, Florida, Kansas, Maryland, Massachusetts, Minnesota, Missouri
2020-04-16
By invitation
ODYSSEY: A Study to Investigate the Efficacy of Tradipitant in Treating Severe or Critical COVID-19 Infection
NCT04326426Coronavirus Infection
Vanda Pharmaceuticals
Phase 3
300
New York
2020-04-13
Active, closed
Study of HPN217 in Participants With Relapsed/Refractory Multiple Myeloma MK-4002 (MK-4002-001)
NCT04184050Multiple Myeloma in Relapse, Multiple Myeloma, Multiple Myeloma of Bone, Multiple Myeloma With Failed Remission
Harpoon Therapeutics, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Phase 1
100
Arizona, California, Kansas, New York, Oregon, Washington
2020-04-13
Recruiting
Study to Learn More About the Safety and Effectiveness of the Drug VITRAKVI During Routine Use in Patients With TRK Fusion Cancer Which is Locally Advanced or Spread From the Place Where it Started to Other Places in the Body
NCT04142437Locally Advanced or Metastatic Solid Tumor Harboring an NTRK Gene Fusion
Bayer
Observational
150
Arizona, California, Colorado, Connecticut, Florida, Indiana, Kansas, Maine
2020-04-03
Active, closed
Study of Single Agent Belantamab Mafodotin Versus Pomalidomide Plus Low-dose Dexamethasone (Pom/Dex) in Participants With Relapsed/Refractory Multiple Myeloma (RRMM)
NCT04162210Multiple Myeloma
GlaxoSmithKline
Phase 3
325
Arizona, Colorado, Michigan, Nebraska, New York, Ohio, Oregon, Texas
2020-04-02
Active, closed
A Study of H3B-6545 in Combination With Palbociclib in Women With Advanced or Metastatic Estrogen Receptor-Positive Human Epidermal Growth Factor Receptor-2 (HER2)-Negative Breast Cancer
NCT04288089Receptors, Estrogen, Genes, Erbb-2, Breast Neoplasms
Eisai Inc.
Phase 1
31
Florida, Massachusetts, Missouri, Nevada, Tennessee
2020-04-01
Recruiting
Clinical Utility of WATS3D: A 5-Year Prospective Study
NCT04312633Barrett Esophagus, Gastro Esophageal Reflux, Esophageal Dysplasia, Esophageal Diseases
CDx Diagnostics
Observational
90,000
New York
2020-04-01
Active, closed
GDNF Gene Therapy for Parkinson's Disease
NCT04167540Parkinson's Disease
Brain Neurotherapy Bio, Inc.
Phase 1
11
California, Ohio
2020-04-01
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Priya Life Science (2026). Clinical trial register: industry-sponsored studies with a US investigative site. Derived from ClinicalTrials.gov. Retrieved 23 September 2026. https://priyalifescience.com/clinical-trials-usa?page=82

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