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Trackers› Clinical trials› USA
Clinical trial register · United States · industry-sponsored

Industry-sponsored studies with a US investigative site

Every industry-sponsored study on the ClinicalTrials.gov registry that lists a US site and is open, about to open, active-but-closed, or enrolling by invitation. This deliberately excludes academic and other non-industry sponsors โ€” the full US registry across all sponsors runs to over 22,000 recruiting studies alone.

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Source: ClinicalTrials.gov. Complete coverage of the industry-sponsored slice โ€” all 9112 matching records are in this view (non-industry sponsors are out of scope by design, not truncated). Synced 23 Sep 2026, 03:16 UTC
9112
Studies in scope
industry-sponsored, all four open statuses
4950
Recruiting now
open to new participants
2202
Lead sponsors
across recruiting studies
Top states
California 5295 Florida 4397 Illinois 2479 Georgia 2346 Arizona 2231
Narrow the register
Recruitment status
Phase
Lead sponsor
AstraZeneca299 Novartis Pharmaceuticals202 Eli Lilly and Company190 Merck Sharp & Dohme LLC183 AbbVie172
State
California5295 Florida4397 Illinois2479 Georgia2346 Arizona2231
All 51 states
Target enrolment
to
9112 of 9112 studies
Download
Status
Study
Lead sponsor
Phase
Enrol
US states
Start
Not yet open
Measuring the Impact of Onco4Dยฎ Guidance on Chemotherapy Selection and Outcomes
NCT04891952Cancer, Chemotherapy Effect
Animated Dynamics, Inc.
Observational
1,000
Indiana
2021-08-01
Recruiting
Reducing Pregnancy Risks: The Mastery Lifestyle Intervention
NCT05012072Mental Health Wellness 1, Preterm Birth
Microgen LLC
Not applicable
238
Texas
2021-08-01
Active, closed
MIRACLE of LIFE Study
NCT06074601Preterm Labor, Preterm Birth, Preterm Birth Complication, Preterm Premature Rupture of Membrane
Mirvie
Observational
10,000
California, Florida, Louisiana, Massachusetts, Missouri, Ohio, Pennsylvania, Texas
2021-08-01
Active, closed
A Novel Computer-Based Functional Skills Assessment and Training Program
NCT04679441Mild Cognitive Impairment, Healthy Aging
i-Function, Inc.
Phase 2
180
Florida, New York
2021-08-01
Recruiting
A Study of 177Lu-FAP-2286 in Advanced Solid Tumors
NCT04939610Solid Tumor
Novartis Pharmaceuticals
Phase 1/2
222
Alabama, California, Florida, Illinois, Iowa, Michigan, Minnesota, Missouri
2021-07-30
Recruiting
Study to Evaluate Pregnancy Outcomes in Risankizumab Exposed Pregnancies Relative to Those Non-risankizumab Exposed Pregnancies in Women With FDA Approved Indications
NCT04846959Plaque Psoriasis, Psoriatic Arthritis, Crohn's Disease, or Other Conditions for Which Risankizumab is an FDA-approved Treatment
AbbVie
Observational
818
North Carolina
2021-07-30
Active, closed
Sub-study of Belantamab Mafodotin (GSK2857916) in Combination With Isatuximab in Participants With RRMM
NCT07217184Multiple Myeloma
GlaxoSmithKline
Phase 1/2
30
Georgia, Massachusetts, Michigan, Wisconsin
2021-07-29
Recruiting
Zimmer Biomet Shoulder Arthroplasty PMCF
NCT04984291Shoulder Fractures, Shoulder Arthritis, Shoulder Osteoarthritis, Shoulder Deformity
Zimmer Biomet
Not applicable
584
California, Colorado, Illinois, Kentucky, Michigan, Minnesota, Mississippi, Missouri
2021-07-28
Recruiting
Study of Efficacy and Safety of Iptacopan in Patients With C3 Glomerulopathy.
NCT04817618C3G
Novartis Pharmaceuticals
Phase 3
98
Colorado, Florida, Georgia, Indiana, Iowa, Maryland, Massachusetts, New Jersey
2021-07-28
Active, closed
Long-term Safety and Tolerability of Iptacopan in Patients With Paroxysmal Nocturnal Hemoglobinuria
NCT04747613Paroxysmal Nocturnal Hemoglobinuria
Novartis Pharmaceuticals
Phase 3
208
California, Florida, Georgia, New York, Ohio, South Carolina
2021-07-27
By invitation
A Study to Evaluate the Safety and Tolerability of Dapirolizumab Pegol in Study Participants With Systemic Lupus Erythematosus
NCT04976322Systemic Lupus Erythematosus
UCB Biopharma SRL
Phase 3
760
Alabama, Arizona, California, Colorado, Florida, Georgia, Idaho, Illinois
2021-07-27
Recruiting
EFS of the CardioMech MVRS
NCT04820764Mitral Regurgitation
CardioMech AS
Not applicable
25
California, Illinois, Kansas, Minnesota, New York, North Carolina, Ohio, Tennessee
2021-07-27
Active, closed
M6-C Artificial Cervical Disc Two-Level IDE Pivotal Study
NCT04982835Cervical Disc Degenerative Disorder
Orthofix Inc.
Not applicable
156
Arizona, California, Colorado, Florida, Georgia, Idaho, Illinois, Massachusetts
2021-07-26
Active, closed
ALTUS: Performance of a Multi- Target Hepatocellular Carcinoma (HCC) Test in Subjects With Increased Risk
NCT05064553Hepatocellular Carcinoma, Hepatocellular Cancer, Hepatitis B, Cirrhosis
Exact Sciences Corporation
Observational
2,990
Arizona, California, Colorado, District of Columbia, Florida, Illinois, Indiana, Iowa
2021-07-26
Active, closed
Phase 0 Master Protocol for CIVO Intratumoral Microdosing of Anti-Cancer Therapies
NCT04541108Solid Tumor
Presage Biosciences
Phase EARLY_PHASE1
15
Louisiana, New York, North Carolina, Ohio, Oregon, Pennsylvania, South Carolina, Washington
2021-07-26
Recruiting
A Study Evaluating the Safety, Pharmacokinetics, and Activity of Cevostamab in Participants With Relapsed or Refractory Multiple Myeloma
NCT04910568Multiple Myeloma
Genentech, Inc.
Phase 1
186
California, Colorado, Georgia, Michigan, Missouri
2021-07-26
Active, closed
Study to Evaluate Adverse Events and Change in Disease Activity in Participants Between 6 and 17 Years With Moderate to Severe Plaque Psoriasis Treated With Subcutaneous (SC) Injection of Risankizumab Who Have Completed Participation in Study M19-977
NCT04862286Psoriasis
AbbVie
Phase 3
132
Alabama, California, Florida, Illinois, Nevada, Ohio, South Carolina, West Virginia
2021-07-24
Active, closed
Phase I Study to Assess the Effect of Food on the PK and Gastrointestinal Tolerability of Selumetinib in Adolescent Children With Neurofibromatosis Type 1 Related Plexiform Neurofibromas
NCT05101148Neurofibromatosis Type 1
AstraZeneca
Phase 1
24
Minnesota, Ohio
2021-07-21
Recruiting
A Study to Evaluate the Benefits and Risks of Conversion of Existing Adolescent Kidney Transplant Recipients Aged 12 to <18 Years to a Belatacept-based Immunosuppressive Regimen as Compared to Continuation of a Calcineurin Inhibitor-based Regimen, and Their Adherence to Immunosuppressive Medications
NCT04877288Renal Allograft Recipients
Bristol-Myers Squibb
Phase 3
102
Alabama, California, District of Columbia, Florida, Georgia, Illinois, Maryland, Massachusetts
2021-07-21
Active, closed
Effectiveness of the EMPOWERโ„ข Modular Pacing System and EMBLEMโ„ข Subcutaneous ICD to Communicate Antitachycardia Pacing
NCT04798768Tachycardia, Ventricular, Arrhythmia, Ventricular
Boston Scientific Corporation
Not applicable
297
Arizona, Arkansas, Florida, Georgia, Kentucky, Minnesota, New Jersey, New York
2021-07-20
Recruiting
Registry of Arthrex Hand and Wrist Products
NCT05046600Ulnar/Radial Collateral Ligament Reconstruction, Ligament Repair or Reconstruction, Small Bone Fragments and Arthrodesis, Scapholunate Ligament Reconstruction
Arthrex, Inc.
Observational
650
Arizona, Iowa, North Carolina, West Virginia
2021-07-20
Active, closed
Rate of Bony Fusion Using NanoBoneยฎ Synthetic Bone Graft Versus Local Autologous Bone Graft.
NCT04615260Degenerative Disc Disease, Spondylolisthesis
Artoss Inc.
Not applicable
40
Massachusetts
2021-07-19
Active, closed
CYPRESS Efficacy and Safety Study Extension
NCT04947735Juvenile Myopia, Myopia
SightGlass Vision, Inc.
Not applicable
200
California, Florida, Kansas, Louisiana, Missouri, New York, South Dakota, Tennessee
2021-07-19
Recruiting
Study of Oral Administration of LP-168 in Patients With Relapsed or Refractory B-cell Malignancies.
NCT04775745CLL/SLL, Waldenstrom Macroglobulinemia, Follicular Lymphoma, Diffuse Large B Cell Lymphoma
Newave Pharmaceutical Inc
Phase 1
60
North Carolina, Ohio, Utah
2021-07-19
Active, closed
Study of LY3537982 in Cancer Patients With a Specific Genetic Mutation (KRAS G12C)
NCT04956640Carcinoma, Non-Small-Cell Lung, Colorectal Neoplasms, Endometrial Neoplasms, Ovarian Neoplasms
Eli Lilly and Company
Phase 1/2
540
Alabama, California, Connecticut, Florida, Indiana, Louisiana, Massachusetts, New Hampshire
2021-07-19
Active, closed
A Study to Learn About the Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Systemic Lupus Erythematosus
NCT04961567Lupus Erythematosus, Systemic
Biogen
Phase 3
562
Alabama, Arizona, California, Florida, Georgia, Illinois, Massachusetts, Missouri
2021-07-16
Recruiting
A Study Evaluating the Safety, Pharmacokinetics and Early Efficacy of AVA6000 in Solid Tumours
NCT04969835Salivary Gland Tumor, Urothelial Carcinoma, Ovarian Carcinoma, Breast Cancer
Avacta Life Sciences Ltd
Phase 1
158
New York, Texas, Washington
2021-07-16
Recruiting
A Study of Nipocalimab Administered to Adults With Generalized Myasthenia Gravis
NCT04951622Myasthenia Gravis
Janssen Research & Development, LLC
Phase 3
199
Arizona, California, Colorado, Connecticut, Florida, Georgia, Kansas, Massachusetts
2021-07-15
Active, closed
A Study to Determine the Efficacy and Safety of Deucravacitinib Compared With Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Are Naรฏve to Biologic Disease Modifying Anti-rheumatic Drugs or Had Previously Received TNFฮฑ Inhibitor Treatment
NCT04908189Psoriatic Arthritis
Bristol-Myers Squibb
Phase 3
729
Alabama, California, Illinois, Kentucky, Louisiana, Maryland, Michigan, Minnesota
2021-07-15
Active, closed
A Study to Evaluate Tabelecleucel in Participants With Epstein Barr Virus (EBV) Associated Diseases
NCT04554914Epstein-Barr Virus (EBV)-Associated Diseases, EBV+ Lymphoproliferative Disease With Primary Immunodeficiency (EBV+ PID LPD), EBV+ Lymphoproliferative Disease With Acquired (Non-congenital) Immunodeficiency (EBV+ AID LPD), EBV+ Posttransplant Lymphoproliferative Disease in Central Nervous System (EBV+ CNS PTLD)
Pierre Fabre Medicament
Phase 2
190
California, Florida, Georgia, Illinois, Maryland, Massachusetts, Michigan, Minnesota
2021-07-14
Active, closed
A Study to Determine the Efficacy and Safety of Deucravacitinib Compared With Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Are Naรฏve to Biologic Disease-modifying Anti-rheumatic Drugs
NCT04908202Psoriatic Arthritis
Bristol-Myers Squibb
Phase 3
670
Arizona, Arkansas, California, Colorado, Florida, Georgia, Idaho, Illinois
2021-07-13
Active, closed
Open-label Extension Trial to Evaluate the Long-term Safety of Apraglutide in Short Bowel Syndrome.
NCT05018286Short Bowel Syndrome
VectivBio AG
Phase 3
158
California, Florida, Illinois, Michigan, Minnesota, Nebraska, New York, North Carolina
2021-07-13
Active, closed
A Study of JNJ-78278343, a T-Cell-Redirecting Agent Targeting Human Kallikrein 2 (KLK2), for Advanced Prostate Cancer
NCT04898634Prostatic Neoplasms
Janssen Research & Development, LLC
Phase 1
216
New York, Washington
2021-07-13
Recruiting
Valved Graft PMCF Study
NCT04754217Aortic Valve Disease, Ascending Aorta Abnormality, Aortic Dissection
Abbott Medical Devices
Observational
260
Alabama, Michigan, North Carolina, Pennsylvania
2021-07-13
Active, closed
A Study to Evaluate Efficacy and Safety of Deucravacitinib in Participants With Active Discoid and/or Subacute Cutaneous Lupus Erythematosus (DLE/SCLE)
NCT04857034Lupus Erythematosus, Discoid, Lupus Erythematosus, Subacute Cutaneous
Bristol-Myers Squibb
Phase 2
74
Arizona, California, Connecticut, Florida, Michigan, Missouri, New York, North Carolina
2021-07-12
Recruiting
A Study Evaluating APG-115 as a Single Agent or in Combination With APG-2575 in Subjects With R/R T-PLL and NHL
NCT04496349T-Prolymphocytic Leukemia, Non-Hodgkins Lymphoma
Ascentage Pharma Group Inc.
Phase 2
78
Texas
2021-07-12
Active, closed
FT819 in Subjects With B-cell Malignancies
NCT04629729Lymphoma, B-Cell, Chronic Lymphocytic Leukemia, Precursor B-Cell Acute Lymphoblastic Leukemia
Fate Therapeutics
Phase 1
54
Alabama, Arizona, California, Florida, Iowa, Kansas, Kentucky, Minnesota
2021-07-12
Active, closed
A Phase 3 Study to Evaluate Safety and Biomarkers of Resmetirom (MGL-3196) in Patients With Non-alcoholic Fatty Liver Disease (NAFLD), MAESTRO-NAFLD-Open-Label-Extension (MAESTRO-NAFLD-OLE)
NCT04951219Non-Alcoholic Fatty Liver Disease
Madrigal Pharmaceuticals, Inc.
Phase 3
810
Alabama, Arizona, Arkansas, California, Colorado, Florida, Georgia, Hawaii
2021-07-09
Active, closed
Assessment of Potential for Chronic Liver Injury in Participants Treated With Epidiolex (Cannabidiol) Oral Solution
NCT05044819Lennox Gastaut Syndrome, Dravet Syndrome, Tuberous Sclerosis Complex
Jazz Pharmaceuticals
Phase 4
154
Arkansas, California, Florida, Georgia, Kansas, Kentucky, Maryland, Massachusetts
2021-07-07
Active, closed
Post-Market Clinical Follow-Up onTVT EXACTยฎ Continence System
NCT04829994Stress Urinary Incontinence
Ethicon, Inc.
Observational
198
North Carolina, Pennsylvania
2021-07-07
Active, closed
G7 Acetabular System With Vivacit-E or Longevity Liner PMCF Study
NCT04754087Total Hip Arthroplasty, Degenerative Joint Disease of Hip, Avascular Necrosis of Hip, Rheumatoid Arthritis of Hip
Zimmer Biomet
Not applicable
300
Colorado, Indiana, North Carolina, Oregon, Utah
2021-07-07
Recruiting
A Novel Vaccine (EO2463) as Monotherapy and in Combination, for Treatment of Patients With Indolent Non-Hodgkin Lymphoma
NCT04669171Follicular Lymphoma, Marginal Zone Lymphoma
Enterome
Phase 1/2
80
Massachusetts, Minnesota, New York, Washington
2021-07-05
Active, closed
Beamion LUNG-1: A Study to Test Different Doses of Zongertinib in People With Different Types of Advanced Cancer (Solid Tumours With Changes in the HER2 Gene)
NCT04886804Neoplasm Metastasis, Non-Small Cell Lung Cancer
Boehringer Ingelheim
Phase 1
554
Alabama, California, District of Columbia, Florida, Georgia, Hawaii, New York, North Carolina
2021-07-02
Active, closed
Triathlon All-Polyethylene Tibia Outcomes Study
NCT04636190Arthropathy of Knee, Replacement, Knee Arthritis
Stryker Orthopaedics
Not applicable
204
Michigan, New York, North Carolina, Ohio, Texas
2021-07-02
Active, closed
Ovarian Suppression Evaluating Subcutaneous Leuprolide Acetate in Breast Cancer
NCT04906395Breast Cancer
Tolmar Inc.
Phase 3
250
California, Colorado, Illinois, Kentucky, Maryland, Nebraska, New York, Ohio
2021-07-01
Recruiting
BostonGene-Integrated Genomic Registry (BIGR)
NCT04991922Malignancy
BostonGene
Observational
100,000
Massachusetts
2021-07-01
Active, closed
A Study of Gene Therapy for Classic Congenital Adrenal Hyperplasia (CAH)
NCT04783181Congenital Adrenal Hyperplasia
Adrenas Therapeutics Inc
Phase 1/2
8
Illinois, Maryland, Minnesota, North Carolina, Pennsylvania
2021-07-01
Active, closed
Safety and Efficacy of the CGuardโ„ข Carotid Stent System in Carotid Artery Stenting
NCT04900844Carotid Artery Stenosis
InspireMD
Not applicable
317
Florida, Louisiana, Michigan, Missouri, New York, North Carolina, Ohio, Pennsylvania
2021-07-01
Active, closed
Study on an Investigational Yellow Fever Vaccine Compared With YF-VAX in Adults in the USA
NCT04942210Yellow Fever, Healthy Volunteers
Sanofi Pasteur, a Sanofi Company
Phase 2
568
Georgia, Louisiana, Maryland, Massachusetts, Missouri, Nebraska, New York, Rhode Island
2021-07-01
Recruiting
A Study to Evaluate the Safety and Efficacy of EscharEx (EX-02) in the Treatment of Basal Cell Carcinoma
NCT05157763Superficial Basal Cell Carcinoma, Nodular Basal Cell Carcinoma
MediWound Ltd
Phase 1/2
32
Florida, Texas
2021-06-30
Active, closed
CardiAMP Cell Therapy Chronic Myocardial Ischemia Trial
NCT03455725Refractory Angina, Chronic Myocardial Ischemia
BioCardia, Inc.
Not applicable
343
Florida, Wisconsin
2021-06-30
Recruiting
A Study With Eptinezumab in Adolescents (12-17 Years) With Chronic Migraine
NCT04965675Chronic Migraine in Children
H. Lundbeck A/S
Phase 3
285
Connecticut, District of Columbia, Florida, Georgia, Kentucky, Maryland, Michigan, New York
2021-06-30
Active, closed
Assessment of Chimerism and Relapse Post Bone Marrow/Hematopoietic Cell Transplant (HCT) Using AlloHeme Test
NCT04635384Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndrome
CareDx
Observational
307
California, Florida, Georgia, Massachusetts, Missouri, New York, Ohio, Oregon
2021-06-30
Active, closed
Phase III Study to Assess AZD9833+ CDK4/6 Inhibitor in HR+/HER2-MBC With Detectable ESR1m Before Progression (SERENA-6)
NCT04964934ER-Positive HER2-Negative Breast Cancer
AstraZeneca
Phase 3
315
Arizona, Arkansas, California, Colorado, Florida, Georgia, Illinois, Indiana
2021-06-30
Recruiting
Study of TJ033721 (Givastomig) in Subjects With Advanced or Metastatic Solid Tumors
NCT04900818Solid Tumor, Advanced Cancer, Metastatic Cancer, Gastric Cancer
I-Mab Biopharma US Limited
Phase 1
330
California, Colorado, Indiana, Massachusetts, New Jersey, New York, North Carolina, Tennessee
2021-06-29
Active, closed
Phase 1/2 Clinical Trial of PR001 in Infants With Type 2 Gaucher Disease (PROVIDE)
NCT04411654Gaucher Disease, Type 2
Prevail Therapeutics
Phase 1/2
7
California, Minnesota, New York, Pennsylvania, Virginia
2021-06-29
Recruiting
Gut Microbiome and Treatment for Gynecological Cancer Patients Receiving Immunotherapy
NCT04957511Gynecologic Cancer, Immunotherapy, Gut Microbiome
Viome
Observational
30
Florida
2021-06-29
Recruiting
CORCYM Mitral, Aortic aNd Tricuspid Post-maRket Study in a reAl-world Setting
NCT05002543Cardiac Valve Disease
Corcym S.r.l
Observational
2,150
Indiana, Louisiana, Maine, North Carolina, Ohio, Pennsylvania
2021-06-29
Active, closed
Study of Lenacapavir for HIV Pre-Exposure Prophylaxis in People Who Are at Risk for HIV Infection
NCT04925752Pre-Exposure Prophylaxis of HIV Infection
Gilead Sciences
Phase 3
3,292
Alabama, California, Colorado, Connecticut, District of Columbia, Florida, Georgia, Illinois
2021-06-28
Active, closed
Study to Assess the Safety, Tolerability, and Efficacy of IDX-1197 in Combination With XELOX or Irinotecan in Patients With Advanced Gastric Cancer
NCT04725994Gastric Cancer
Idience Co., Ltd.
Phase 1/2
87
California, Louisiana, Massachusetts, New Jersey
2021-06-28
Active, closed
Efficacy and Safety Comparison of Niraparib to Placebo in Participants With Human Epidermal Growth Factor 2 Negative (HER2-) Breast Cancer Susceptibility Gene Mutation (BRCAmut) or Triple-Negative Breast Cancer (TNBC) With Molecular Disease
NCT04915755Neoplasms, Breast
GlaxoSmithKline
Phase 3
40
California, Colorado, Illinois, Michigan, New Mexico, New York, North Dakota, Pennsylvania
2021-06-28
Active, closed
Evaluation of Lomecel-Bโ„ข Injection in Patients With Hypoplastic Left Heart Syndrome (HLHS): A Phase IIb Clinical Trial.
NCT04925024Hypoplastic Left Heart Syndrome
Longeveron Inc.
Phase 2
40
California, Colorado, Georgia, Illinois, Massachusetts, Nebraska, Ohio, Pennsylvania
2021-06-25
Active, closed
A Study Evaluating the Efficacy and Safety of Obinutuzumab in Participants With Primary Membranous Nephropathy
NCT04629248Primary Membranous Nephropathy
Hoffmann-La Roche
Phase 3
142
California, Colorado, Florida, Iowa, Michigan, Minnesota, New York, Texas
2021-06-25
Recruiting
Study of the Long-Term Safety and Outcomes of Treating Pulmonary Embolism With the Indigo Aspiration System
NCT04798261Pulmonary Embolism
Penumbra Inc.
Observational
1,500
California, Delaware, District of Columbia, Florida, Georgia, Illinois, Kansas, Louisiana
2021-06-25
Active, closed
Evaluation of Co-formulated Pembrolizumab/Quavonlimab (MK-1308A) Versus Other Treatments in Participants With Microsatellite Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Stage IV Colorectal Cancer (CRC) (MK-1308A-008/KEYSTEP-008).
NCT04895722Colorectal Cancer
Merck Sharp & Dohme LLC
Phase 2
302
Florida, Georgia, Illinois, New York, Pennsylvania, Tennessee, Texas, Washington
2021-06-25
Active, closed
A Study of CDPATHโ„ข to Help Manage and Treat Crohn's Disease
NCT04809363Crohn's Disease
Takeda
Phase 4
200
Arizona, California, Colorado, Connecticut, Florida, Idaho, Illinois, Indiana
2021-06-25
Active, closed
Global Safety and Efficacy Registration Study of Crinecerfont in Pediatric Participants With Classic Congenital Adrenal Hyperplasia (CAHtalyst Pediatric Study)
NCT04806451Congenital Adrenal Hyperplasia
Neurocrine Biosciences
Phase 3
103
Alabama, California, Colorado, Connecticut, District of Columbia, Georgia, Indiana, Massachusetts
2021-06-25
Active, closed
Phase 3 Study of MRTX849 With Cetuximab vs Chemotherapy in Patients With Advanced Colorectal Cancer With KRAS G12C Mutation (KRYSTAL-10)
NCT04793958Advanced Colorectal Cancer, Metastatic Colorectal Cancer
Mirati Therapeutics Inc.
Phase 3
461
Alabama, Arizona, Arkansas, California, Colorado, Connecticut, Florida, Georgia
2021-06-24
Recruiting
A Study to Assess the Long-Term Safety of Ustekinumab Versus Other Biologics in Patients With Crohn's Disease and Ulcerative Colitis
NCT04372108Crohn Disease, Colitis, Ulcerative
Janssen Scientific Affairs, LLC
Observational
1,536
Texas
2021-06-24
Active, closed
Effects of Hypoglossal Nerve Stimulation on Cognition and Language in Down Syndrome and Obstructive Sleep Apnea
NCT04801771Down Syndrome, Obstructive Sleep Apnea
Inspire Medical Systems, Inc.
Not applicable
57
Georgia, Massachusetts, Ohio, Pennsylvania, Texas, Virginia, Wisconsin
2021-06-24
Recruiting
WE-TRUST (Workflow Optimization to Reduce Time to Endovascular Reperfusion for Ultra-fast Stroke Treatment)
NCT04701684Stroke, Acute
Philips Clinical & Medical Affairs Global
Not applicable
594
Florida, Georgia, New York
2021-06-23
Active, closed
A Study of T-DXd in Participants With or Without Brain Metastasis Who Have Previously Treated Advanced or Metastatic HER2 Positive Breast Cancer
NCT04739761Breast Cancer
AstraZeneca
Phase 3
506
Massachusetts, North Carolina
2021-06-22
Recruiting
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Participants With Breast Cancer
NCT04802759Inoperable, Locally Advanced or Metastatic, ER-positive Breast Cancer
Hoffmann-La Roche
Phase 1/2
316
California, Massachusetts, New Jersey, North Carolina, Pennsylvania, Tennessee
2021-06-22
Active, closed
QUILT-3.076: Study of Autologous M-CENK in Subjects With Locally Advanced or Metastatic Solid Tumors
NCT04898543Metastatic Solid Tumor
ImmunityBio, Inc.
Phase 1
50
California
2021-06-21
Active, closed
MIT-001 for Prevention of CCRT-Induced OM in HNSCC Patients
NCT04651634Head and Neck Squamous Cell Carcinoma, Oral Mucositis
MitoImmune Therapeutics
Phase 2
60
Arizona, California, Kansas, New York, North Carolina, Ohio
2021-06-21
Active, closed
Study of Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy for HR+/HER2- Locally Recurrent Inoperable or Metastatic Breast Cancer (MK-3475-B49/KEYNOTE-B49)
NCT04895358Breast Neoplasms
Merck Sharp & Dohme LLC
Phase 3
342
Alabama, Arizona, California, District of Columbia, Florida, Georgia, Illinois, Indiana
2021-06-18
Recruiting
DPX-Survivac and Pembrolizumab With and Without Intermittent Low-Dose Cyclophosphamide, in Subjects With Relapsed/Refractory Diffuse Large B-Cell Lymphoma
NCT04920617Relapsed Diffuse Large B-cell Lymphoma, Refractory Diffuse Large B-cell Lymphoma
ImmunoVaccine Technologies, Inc. (IMV Inc.)
Phase 2
102
California, Florida, Georgia, Indiana, Louisiana, Nebraska, New Mexico, North Carolina
2021-06-18
Active, closed
A Study of Guselkumab in Participants With Active Psoriatic Arthritis
NCT04882098Arthritis, Psoriatic
Janssen Research & Development, LLC
Phase 3
1,054
Alabama, Arizona, California, Florida, Maryland, Michigan, Missouri, Montana
2021-06-17
By invitation
Distal Evaluation of Functional Performance with Intravascular Sensors to Assess the Narrowing Effect: Guided Physiologic Stenting
NCT04451044Coronary Artery Disease, Ischemic Heart Disease
Philips Clinical & Medical Affairs Global
Not applicable
3,212
Alabama, Arizona, Arkansas, California, Colorado, Connecticut, District of Columbia, Florida
2021-06-17
By invitation
Long-Term Follow-Up of Patients Who Received Gene-Modified Cell Therapy
NCT05472649Long-term Follow-up
Sorrento Therapeutics, Inc.
Observational
1
Pennsylvania
2021-06-16
Active, closed
177Lu-PSMA-617 vs. Androgen Receptor-Directed Therapy in the Treatment of Progressive Metastatic Castrate Resistant Prostate Cancer
NCT04689828Prostatic Neoplasms
Novartis Pharmaceuticals
Phase 3
469
Colorado, Florida, Louisiana, Massachusetts, Missouri, Nebraska, New York, North Carolina
2021-06-15
Active, closed
FUSION: A Study to Evaluate the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of ION363 in Amyotrophic Lateral Sclerosis Participants With Fused in Sarcoma Mutations (FUS-ALS)
NCT04768972Amyotrophic Lateral Sclerosis
Ionis Pharmaceuticals, Inc.
Phase 3
89
California, Maryland, Massachusetts, Missouri, New York, Ohio, Utah
2021-06-14
Recruiting
A Safety and Dose-finding Study of PRL-02 Depot in Men With Advanced Prostate Cancer
NCT04729114Prostate Cancer, Metastatic Castration Resistant Prostate Cancer, Metastatic Castration-sensitive Prostate Cancer
Astellas Pharma Global Development, Inc.
Phase 1
174
Arizona, California, Florida, Indiana, Kansas, Maryland, Nebraska, New Jersey
2021-06-14
Active, closed
FHD-286 as Monotherapy or Combination Therapy in Subjects With Advanced Hematologic Malignancies
NCT04891757Advanced Hematologic Malignancy, Relapsed Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia, Relapsed Myelodysplastic Syndromes
Foghorn Therapeutics Inc.
Phase 1
144
California, Massachusetts, New York, Tennessee, Texas
2021-06-14
Recruiting
Persona Revision Knee System Outcomes
NCT04821154Arthroplasty Complications, Infection, Knee Disease, Knee Osteoarthritis
Zimmer Biomet
Observational
380
Arkansas, California, Colorado, Indiana, Kentucky, Michigan, Minnesota, Missouri
2021-06-14
Active, closed
HER3-DXd (Patritumab Deruxtecan; U3-1402) in Combination With Osimertinib in Subjects With Locally Advanced or Metastatic EGFR-mutated Non-Small Cell Lung Cancer
NCT04676477Non-Small Cell Lung Cancer (NSCLC)
Daiichi Sankyo
Phase 1
246
California, Connecticut, District of Columbia, Illinois, Massachusetts, Michigan, New Hampshire, New York
2021-06-11
Active, closed
Assessing Outcomes With Microprocessor Knee Utilization in a K2 Population
NCT04784429Lower Limb Amputation Above Knee (Injury), Congenital Amputation of Lower Limb, Lower Limb Amputation Knee
Otto Bock Healthcare Products GmbH
Not applicable
107
Alabama, Arizona, California, Colorado, Florida, Georgia, Illinois, Indiana
2021-06-11
Recruiting
Device Global Registry for the IlluminOss Bone Stabilization System
NCT05206981Traumatic Fracture, Pathological Fracture
IlluminOss Medical, Inc.
Observational
300
Alabama, California, Colorado, Florida, Indiana, New York, North Carolina, Pennsylvania
2021-06-11
Active, closed
Long-term Use of Viltolarsen in Boys With Duchenne Muscular Dystrophy in Clinical Practice (VILT-502)
NCT04687020Duchenne Muscular Dystrophy
NS Pharma, Inc.
Phase 4
9
California, Illinois, North Carolina, Virginia
2021-06-10
Recruiting
Rollover Study for Patients With Sickle Cell Disease Who Have Completed a Prior Novartis-Sponsored Crizanlizumab Study
NCT04657822Sickle Cell Disease
Novartis Pharmaceuticals
Phase 4
130
Alabama, District of Columbia, Georgia, North Carolina, Pennsylvania, Texas
2021-06-10
Active, closed
A Prospective Study to Observe & Describe Clinical Outcomes of Alglucosidase Alfa Treatment in Patients โ‰ค6 Months of Age With Infantile-onset Pompe Disease (IOPD)
NCT04848779Glycogen Storage Disease Type II
Sanofi
Observational
16
New York, North Carolina, Ohio, Tennessee, Washington
2021-06-10
Active, closed
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral GB2064 in Participants With Myelofibrosis
NCT04679870Myelofibrosis
Galecto Biotech AB
Phase 2
21
Texas
2021-06-09
Active, closed
An International Prospective Open-label, Randomized, Phase III Study Comparing 177Lu-PSMA-617 in Combination With Standard of Care (SoC), Versus SoC Alone, in Adult Male Patients With Metastatic Hormone Sensitive Prostate Cancer (mHSPC)
NCT04720157Prostatic Neoplasms
Novartis Pharmaceuticals
Phase 3
1,140
Arizona, California, Colorado, Connecticut, District of Columbia, Florida, Georgia, Hawaii
2021-06-09
Active, closed
Subcutaneous Anifrolumab in Adult Patients With Systemic Lupus Erythematosus
NCT04877691Systemic Lupus Erythematosus
AstraZeneca
Phase 3
367
Alabama, Arizona, California, Colorado, Florida, Idaho, Michigan, New Jersey
2021-06-08
Recruiting
A Study of BTX-A51 in People With Advanced Solid Tumor and Breast Cancer
NCT04872166Advanced Solid Tumor, Metastatic Breast Cancer
Edgewood Oncology Inc.
Phase 1
112
Florida, Ohio, Tennessee, Texas
2021-06-07
Active, closed
Proof-of-concept Study for SAR441344 (Frexalimab) in Relapsing Multiple Sclerosis
NCT04879628Multiple Sclerosis
Sanofi
Phase 2
129
Arizona, Florida, North Carolina, Wisconsin
2021-06-07
Active, closed
da Vinci SPยฎ Investigational Device Exemption Study in Colorectal Procedures
NCT04403022Colorectal Cancer, Benign or Malignant Rectal or Colon Tumors
Intuitive Surgical
Not applicable
60
Florida, Michigan, Minnesota, Nevada, Pennsylvania, Texas, Washington
2021-06-03
Active, closed
Valemetostat Tosylate (DS-3201b), an Enhancer of Zeste Homolog (EZH) 1/2 Dual Inhibitor, for Relapsed/Refractory Peripheral T-Cell Lymphoma (VALENTINE-PTCL01)
NCT04703192Relapsed/Refractory Peripheral T-Cell Lymphoma, Adult T Cell Leukemia/Lymphoma
Daiichi Sankyo
Phase 2
155
California, Colorado, Georgia, Illinois, Massachusetts, Minnesota, Missouri, New Jersey
2021-06-03
Recruiting
Safety, Efficacy, & Use of ViviGen Cellular Bone Matrix Allograft in Orthopaedic Fracture Care
NCT04299022Fractures, Bone, Nonunion of Fracture, Fractures, Open, Fractures, Ununited
LifeNet Health
Observational
250
Florida, New Jersey, North Carolina, Virginia
2021-06-01
Recruiting
A Non-randomized, Open-Label Study to Evaluate the Safety and Effectiveness of the Dayspring Technology for Patients With Breast Cancer Related Lymphedema (BCRL) After Lymphatic Surgery
NCT04888975Lymphedema, Lymphedema, Breast Cancer, Lymphedema Arm
Koya Medical, Inc.
Not applicable
20
California
2021-06-01
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Priya Life Science (2026). Clinical trial register: industry-sponsored studies with a US investigative site. Derived from ClinicalTrials.gov. Retrieved 23 September 2026. https://priyalifescience.com/clinical-trials-usa?page=77

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