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Trackers› Clinical trials› USA
Clinical trial register · United States · industry-sponsored

Industry-sponsored studies with a US investigative site

Every industry-sponsored study on the ClinicalTrials.gov registry that lists a US site and is open, about to open, active-but-closed, or enrolling by invitation. This deliberately excludes academic and other non-industry sponsors โ€” the full US registry across all sponsors runs to over 22,000 recruiting studies alone.

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Source: ClinicalTrials.gov. Complete coverage of the industry-sponsored slice โ€” all 9110 matching records are in this view (non-industry sponsors are out of scope by design, not truncated). Synced 22 Sep 2026, 03:16 UTC
9110
Studies in scope
industry-sponsored, all four open statuses
4947
Recruiting now
open to new participants
2198
Lead sponsors
across recruiting studies
Top states
California 5292 Florida 4393 Illinois 2478 Georgia 2343 Arizona 2230
Narrow the register
Recruitment status
Phase
Lead sponsor
AstraZeneca299 Novartis Pharmaceuticals202 Eli Lilly and Company190 Merck Sharp & Dohme LLC183 AbbVie172
State
California5292 Florida4393 Illinois2478 Georgia2343 Arizona2230
All 51 states
Target enrolment
to
9110 of 9110 studies
Download
Status
Study
Lead sponsor
Phase
Enrol
US states
Start
Active, closed
A Study to Learn More About The Safety of Diroximel Fumarate (VUMERITYยฎ) in Participants Who Took it During Pregnancy And About the Health of Their Babies
NCT05688436Multiple Sclerosis
Biogen
Observational
1,178
Minnesota
2021-09-24
Active, closed
Placebo Microneedles in Healthy Volunteers (Part I) and Efficacy/Safety of Doxorubicin Microneedles in Basal Cell Cancer Subjects (Part II)
NCT04928222Basal Cell Carcinoma
SkinJect, Inc.
Phase 1/2
25
Florida, New York
2021-09-24
Recruiting
Observational Study to Assess Maternal, Fetal and Infant Outcomes Following Exposure to Rimegepant
NCT05046613Migraine
Pfizer
Observational
780
North Carolina
2021-09-23
Recruiting
Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Reduced Ejection Fraction
NCT04703842Congestive Heart Failure, Heart Failure, Systolic, Heart Failure, HFrEF - Heart Failure With Reduced Ejection Fraction
Sardocor Corp.
Phase 1/2
57
California, Missouri, Texas, Washington
2021-09-23
Active, closed
Study of INBRX-109 in Conventional Chondrosarcoma
NCT04950075Conventional Chondrosarcoma
Inhibrx Biosciences, Inc
Phase 2
206
Arizona, California, Colorado, Connecticut, Florida, Illinois, Iowa, Maryland
2021-09-23
Recruiting
Innovations in Genicular Outcomes Registry
NCT05495334Knee Osteoarthritis
Pacira Pharmaceuticals, Inc
Observational
10,000
Arizona, California, Florida, Louisiana, Maryland, Massachusetts, Nebraska, New Jersey
2021-09-23
Active, closed
A Study of Pirtobrutinib (LOXO-305) Versus Bendamustine Plus Rituximab (BR) in Untreated Patients With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)
NCT05023980Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Loxo Oncology, Inc.
Phase 3
309
California, Florida, New Jersey, New York
2021-09-23
Recruiting
Open-Label, Dose-Escalation With Expansion to Assess the Safety, Tolerability, and PK of TRE-515 in Subjects With Solid Tumors
NCT05055609Solid Tumor, Adult, Oncology
Trethera
Phase 1
94
California, North Carolina
2021-09-23
Active, closed
A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Biliary Cholangitis
NCT05050136Primary Biliary Cholangitis, PBC
Mirum Pharmaceuticals, Inc.
Phase 2
333
California, Colorado, Connecticut, Florida, Georgia, Illinois, Iowa, Louisiana
2021-09-22
Active, closed
A Study to Evaluate Safety and Efficacy of ACT001 and Anti-PD-1 in Patients With Surgically Accessible Recurrent Glioblastoma Multiforme
NCT05053880Recurrent Glioblastoma Multiforme(GBM)
Accendatech USA Inc.
Phase 1/2
48
Texas
2021-09-22
Active, closed
A Study of Talquetamab With Other Anticancer Therapies in Participants With Multiple Myeloma
NCT05050097Multiple Myeloma
Janssen Research & Development, LLC
Phase 1
166
Alabama, California, Colorado, Georgia, Indiana, New Jersey, New York, North Carolina
2021-09-22
Active, closed
Assessment of Safety and Effectiveness of NovoSorbยฎ BTM in Severe Burns
NCT04090424Burns
PolyNovo Biomaterials Pty Ltd.
Not applicable
150
Arizona, California, Connecticut, District of Columbia, Florida, Georgia, Illinois, Iowa
2021-09-21
Active, closed
A Trial of Pirtobrutinib (LOXO-305) Plus Venetoclax and Rituximab (PVR) Versus Venetoclax and Rituximab (VR) in Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)
NCT04965493Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Loxo Oncology, Inc.
Phase 3
600
Arizona, California, Connecticut, Florida, Iowa, Kentucky, Maryland, Massachusetts
2021-09-20
Recruiting
JAGUAR Trial: ObJective Analysis to GaUge EVAR Outcomes Through Randomization
NCT05064540AAA, AAA - Abdominal Aortic Aneurysm
Endologix
Not applicable
450
Alabama, Arizona, Arkansas, California, District of Columbia, Florida, Iowa, Kentucky
2021-09-20
Active, closed
A Rollover Extension Program (REP) to Evaluate the Long-term Safety and Tolerability of Open Label Iptacopan/LNP023 in Participants With Primary IgA Nephropathy
NCT04557462Primary IgA Nephropathy
Novartis Pharmaceuticals
Phase 3
448
Arizona, California, Colorado, Idaho, Illinois, Maryland, Massachusetts, Minnesota
2021-09-20
Active, closed
Determination and Validation of a Multi-analyte Assay for Lung Cancer Screening
NCT04968548Lung Cancer
Nucleix Ltd.
Observational
5,000
California, Colorado, Connecticut, Florida, Kentucky, Maryland, Massachusetts, Minnesota
2021-09-17
Recruiting
A Phase 1b/2 Study of Sonrotoclax (BGB-11417) as Monotherapy and in Various Combinations With Dexamethasone Plus Carfilzomib, Dexamethasone Plus Daratumumab, and Dexamethasone Plus Pomalidomide in Multiple Myeloma
NCT04973605Relapsed/Refractory Multiple Myeloma
BeOne Medicines
Phase 1/2
246
Alabama, California, Florida, Georgia, Illinois, Massachusetts, Missouri, New Jersey
2021-09-16
Active, closed
Study of Safety and Efficacy of Iberdomide (CC-220) and CC-99282 Combined With R-CHOP to Treat Lymphoma
NCT04884035Lymphoma, B-Cell
Celgene
Phase 1
224
Alabama, Arizona, California, Florida, Georgia, Kansas, Minnesota, Nebraska
2021-09-15
Active, closed
Open-label, Follow-up of Doravirine/Islatravir (DOR/ISL 100 mg/0.75mg) for Participants With Human Immunodeficiency Virus-1 (HIV-1) Infection (MK-8591A-033)
NCT04776252HIV-1 Infection
Merck Sharp & Dohme LLC
Phase 3
2,000
Arizona, California, District of Columbia, Florida, Georgia, Illinois, Missouri, New Jersey
2021-09-15
Active, closed
A Study to Compare the Response to Treatment With Abatacept vs Adalimumab, on Background Methotrexate, in Adults With Early, Seropositive, and Shared Epitope-positive Rheumatoid Arthritis and an Inadequate Response to Methotrexate
NCT04909801Rheumatoid Arthritis
Bristol-Myers Squibb
Phase 3
338
California, Colorado, Maryland, Minnesota, New Jersey, New York, North Carolina, Oregon
2021-09-15
Active, closed
A Multi-Center Post-Market Data Collection Protocol to Evaluate the Performance of Orthofix Spine Devices
NCT05082090Spinal Disorders/Injuries
Orthofix Inc.
Observational
2,000
California, Louisiana, Mississippi, North Carolina, Rhode Island, Utah, Virginia
2021-09-15
Active, closed
A Study of PBFT02 in Participants With FTD and Mutations in the Granulin Precursor (GRN) or C9ORF72 Genes
NCT04747431Frontotemporal Dementia, FTD, FTD-GRN, Dementia Frontotemporal
Passage Bio, Inc.
Phase 1/2
30
Michigan, Pennsylvania, Tennessee, Texas
2021-09-14
Active, closed
A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Alectinib in Pediatric Participants With ALK Fusion-Positive Solid or CNS Tumors
NCT04774718ALK Fusion-positive Solid or CNS Tumors
Hoffmann-La Roche
Phase 1/2
42
California, Florida, Michigan, Minnesota, New York, Ohio, Tennessee
2021-09-14
Active, closed
A Study of AZD2936 Anti-TIGIT/Anti-PD-1 Bispecific Antibody in Participants With Advanced or Metastatic NSCLC
NCT04995523Non-Small-Cell Lung Carcinoma
AstraZeneca
Phase 1/2
212
Illinois, Minnesota, Virginia
2021-09-14
Recruiting
Helix Research Network
NCT06057181Genetic Predisposition to Disease, Genetics Disease
Helix, Inc
Observational
2,000,000
Indiana, Minnesota, Nebraska, Nevada, New York, North Carolina, Ohio, Pennsylvania
2021-09-13
Active, closed
OCS Heart Perfusion Post-Approval Registry
NCT05047068Transplant
TransMedics
Observational
350
California, Connecticut, Florida, Georgia, Illinois, Kentucky, Massachusetts, Michigan
2021-09-13
Recruiting
A Dose-Escalation and Expansion Study of Tacabrutideg (BGB-16673) in Participants With B-Cell Malignancies
NCT05006716B-cell Malignancy, Marginal Zone Lymphoma, Follicular Lymphoma, Non-Hodgkin Lymphoma
BeOne Medicines
Phase 1/2
645
Alabama, Arizona, California, Colorado, Florida, Georgia, Illinois, Iowa
2021-09-13
Recruiting
Perform Humeral System Study
NCT05067543Osteoarthritis Shoulder, Avascular Necrosis, Post-traumatic Arthrosis of Other Joints, Shoulder Region, Rotator Cuff Tear Arthropathy
Stryker Trauma and Extremities
Observational
300
Kentucky, Minnesota, Missouri, Ohio, South Dakota, Utah
2021-09-12
Active, closed
A Study to Evaluate Chemotherapy Plus Osimertinib Against Chemotherapy Plus Placebo in Patients With Non-small Cell Lung Cancer (NSCLC)
NCT04765059Non-small Cell Lung Cancer
AstraZeneca
Phase 3
98
Maryland, Massachusetts
2021-09-12
Recruiting
CAP-100 for Subjects With Relapsed/Refractory Chronic Lymphocytic Leukemia
NCT04704323Lymphocytic Leukemia, Chronic, SLL
Catapult Therapeutics
Phase 1
18
Massachusetts, North Carolina
2021-09-10
Active, closed
Study of Selinexor Plus DRd for Newly Diagnosed Multiple Myeloma
NCT04782687Multiple Myeloma, Myeloma Multiple, Kahler Disease, Myeloma, Plasma Cell
US Oncology Research
Phase 2
73
Arizona, Colorado, Maryland, New York, Oregon, Texas, Virginia
2021-09-10
Recruiting
Post Market Clinical Follow-up Study on TVT ABBREVOยฎ Continence System
NCT04829357Stress Urinary Incontinence
Ethicon, Inc.
Observational
195
Pennsylvania
2021-09-09
Active, closed
A Study to Test Different Doses of BI 1823911 Alone and Combined With Other Medicines in People With Different Types of Advanced Cancer With KRAS Mutation
NCT04973163Solid Tumors, KRAS Mutation
Boehringer Ingelheim
Phase 1
30
New York, Texas
2021-09-09
Recruiting
Study of CX-5461 in Patients With Solid Tumours and BRCA1/2, PALB2 or Homologous Recombination Deficiency (HRD) Mutation
NCT04890613Advanced Solid Tumor
Senhwa Biosciences, Inc.
Phase 1
52
California, Florida, Massachusetts, New York, Ohio, Pennsylvania
2021-09-08
Recruiting
A Study of AAV9 Gene Therapy in Participants With Canavan Disease (CANaspire Clinical Trial)
NCT04998396Canavan Disease
Aspa Therapeutics
Phase 1/2
26
California, Illinois, Massachusetts, New York
2021-09-08
Active, closed
Study of DSP-0390 in Patients With Recurrent High-Grade Glioma
NCT05023551High Grade Glioma, Glioblastoma Multiforme
Sumitomo Pharma America, Inc.
Phase EARLY_PHASE1
39
California, Massachusetts, Missouri, New Jersey, New York, Utah
2021-09-08
Active, closed
Phase 1 Study of Autologous CD30.CAR-T in Relapsed or Refractory CD30 Positive Non-Hodgkin Lymphoma
NCT04526834Anaplastic Large Cell Lymphoma, Peripheral T Cell Lymphoma, Extranodal NK/T-cell Lymphoma, Diffuse Large B Cell Lymphoma
Tessa Therapeutics
Phase 1
21
California, Tennessee, Texas
2021-09-08
Recruiting
ZEN003694 and Enzalutamide Versus Enzalutamide Monotherapy in Metastatic Castration-Resistant Prostate Cancer
NCT04986423Metastatic Castration-Resistant Prostate Cancer
Zenith Epigenetics
Phase 2
200
California, Colorado, Florida, Louisiana, Maryland, Michigan, New York, North Carolina
2021-09-08
Recruiting
ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
NCT05059444Bladder Carcinoma, Ureter Carcinoma, Renal Pelvis Carcinoma, Non-small Cell Lung Cancer
Guardant Health, Inc.
Observational
2,285
Alabama, Arizona, Arkansas, California, Colorado, Florida, Louisiana, Maine
2021-09-07
Active, closed
A Phase I/II Study of VTX-801 in Adult Patients With Wilson's Disease
NCT04537377Wilson's Disease
Vivet Therapeutics SAS
Phase 1/2
4
California, Connecticut, Florida, Michigan, North Carolina, Texas
2021-09-03
Recruiting
Quaratusugene Ozeplasmid (Reqorsa) and Osimertinib in Patients With Advanced Lung Cancer Who Progressed on Osimertinib
NCT04486833Carcinoma, Non-Small Cell Lung
Genprex, Inc.
Phase 1/2
158
California, Colorado, Illinois, Kentucky, Maryland, New Jersey, Ohio, Texas
2021-09-03
Active, closed
Long-term Safety and Efficacy of Odevixibat in Patients With Alagille Syndrome
NCT05035030Alagille Syndrome
Albireo, an Ipsen Company
Phase 3
62
California, Georgia, Indiana, Maryland, Massachusetts, Missouri, New York, North Carolina
2021-09-03
Active, closed
A Post-Authorization, Long-term Study of Ozanimod Real-world Safety
NCT05605782Multiple Sclerosis, Relapsing-Remitting
Bristol-Myers Squibb
Observational
9,000
Maryland
2021-09-02
Active, closed
A Study of ARV-766 Given by Mouth in Men With Metastatic Prostate Cancer
NCT05067140Prostate Cancer Metastatic
Novartis Pharmaceuticals
Phase 1/2
164
California, Connecticut, Florida, Maryland, Massachusetts, Michigan, New York, Pennsylvania
2021-09-02
Active, closed
Promoting Healing of Nerves Through Electrical Stimulation
NCT04662320Cubital Tunnel Syndrome, Nerve Compression, Nerve Injury, Ulnar Neuropathies
Checkpoint Surgical Inc.
Not applicable
100
California, Illinois, Missouri, Ohio, Wisconsin
2021-09-01
Recruiting
Freedom-1 Study for Chronic Knee Pain
NCT03877653Osteoarthritic Knee Pain
Curonix LLC
Not applicable
100
California, Colorado, Florida, Georgia, Nevada, Ohio, Texas
2021-09-01
Active, closed
A Study of AL102 in Patients With Progressing Desmoid Tumors
NCT04871282Desmoid, Desmoid Tumor
Immunome, Inc.
Phase 2/3
198
Arizona, California, Florida, Illinois, Massachusetts, Michigan, Missouri, New York
2021-09-01
Active, closed
Clinical Study for Treatment-naรฏve IOPD Babies to Evaluate Efficacy and Safety of ERT With Avalglucosidase Alfa
NCT04910776Glycogen Storage Disease Type II
Sanofi
Phase 3
17
California, Minnesota, New York, North Carolina, Ohio, Washington
2021-09-01
Active, closed
Lifestyle Eating and Performance (LEAP) Program for the Treatment of Irritable Bowel Syndrome (IBS)
NCT05178017IBS - Irritable Bowel Syndrome
Oxford Biomedical Technologies, Inc.
Not applicable
60
Florida
2021-09-01
Recruiting
Effect of Early Administration of TXA in Adult Hip Fractures
NCT05047133Postoperative Blood Loss
Ascension Health
Phase 2/3
170
Michigan
2021-09-01
Recruiting
Bempedoic Acid Pregnancy Surveillance Program
NCT05103254Pregnancy, Hyperlipidemias
Esperion Therapeutics, Inc.
Observational
20
North Carolina
2021-09-01
Active, closed
Taletrectinib Phase 2 Global Study in ROS1 Positive NSCLC
NCT04919811Non Small Cell Lung Cancer
Nuvation Bio Inc.
Phase 2
217
California, Florida, Louisiana, Minnesota, New Jersey, Ohio, Tennessee, Texas
2021-09-01
Active, closed
A Study to Evaluate the Safety, Tolerability, and Exploratory Efficacy of IMS001 in Subjects With Multiple Sclerosis
NCT04956744Multiple Sclerosis
ImStem Biotechnology
Phase 1
30
Georgia, Massachusetts, Utah
2021-08-31
Active, closed
Study to Evaluate the Efficacy, Immunogenicity, and Safety of RSVpreF in Adults.
NCT05035212Lower Respiratory Tract Illness
Pfizer
Phase 3
38,861
Alabama, Arizona, California, Colorado, Connecticut, Florida, Georgia, Idaho
2021-08-31
Active, closed
A Study of Guselkumab Administered Subcutaneously in Bio-naive Participants With Active Psoriatic Arthritis Axial Disease
NCT04929210Arthritis, Psoriatic
Janssen Research & Development, LLC
Phase 4
411
Arizona, Arkansas, California, Connecticut, Florida, Illinois, Maryland, Michigan
2021-08-30
Recruiting
The Mitopure Challenge to Detect Levels of Urolithin A in Dried Blood Spots
NCT04985630Healthy Aging, Healthy, Healthy Diet
Amazentis SA
Not applicable
250
California
2021-08-30
Active, closed
A Study Evaluating the Efficacy and Safety of Adjuvant Giredestrant Compared With Physician's Choice of Adjuvant Endocrine Monotherapy in Participants With Estrogen Receptor-Positive, HER2-Negative Early Breast Cancer (lidERA Breast Cancer)
NCT04961996Early Breast Cancer
Hoffmann-La Roche
Phase 3
4,170
Alabama, California, Colorado, Connecticut, Florida, Illinois, Kansas, Kentucky
2021-08-27
Recruiting
A Beta-only IL-2 ImmunoTherapY Study
NCT05086692Advanced Solid Tumor, Unresectable Solid Tumor, Clear Cell Renal Cell Carcinoma, Triple Negative Breast Cancer
Medicenna Therapeutics, Inc.
Phase 1/2
115
California, Florida, Georgia, Michigan, Texas
2021-08-27
Recruiting
Determining Efficacy and Safety of BXCL501 in Agitation Associated With Pediatric Schizophrenia and Bipolar Disorder
NCT05025605Schizophrenia, Schizo-Affective Disorder, Schizophreniform; Schizophrenic, Bipolar Disorder I
BioXcel Therapeutics Inc
Phase 1
140
California, Florida, Georgia, Texas
2021-08-27
Active, closed
A Donanemab (LY3002813) Study in Participants With Preclinical Alzheimer's Disease (TRAILBLAZER-ALZ 3)
NCT05026866Alzheimer Disease
Eli Lilly and Company
Phase 3
2,996
Alabama, Arizona, California, Colorado, Connecticut, Florida, Georgia, Idaho
2021-08-27
Active, closed
MElanoma Research Lymph Node Prediction Implementation National_001
NCT04759781Melanoma
SkylineDx
Observational
1,820
Florida, Georgia, Kentucky, Michigan, Minnesota, New York, North Carolina, Utah
2021-08-25
Recruiting
WAKIXยฎ (Pitolisant) Pregnancy Registry
NCT05536011Pregnancy Related, Narcolepsy
Harmony Biosciences Management, Inc.
Observational
1,329
North Carolina
2021-08-24
Recruiting
Safety and Efficacy of Tideglusib in Congenital or Childhood Onset Myotonic Dystrophy
NCT05004129Congenital Myotonic Dystrophy
AMO Pharma Limited
Phase 2/3
76
Arkansas, California, Illinois, Iowa, New York, Pennsylvania, Utah, Virginia
2021-08-23
Active, closed
REFLECTION: A Clinical Practice Learning Program for Galleriยฎ
NCT05205967Early Detection of Cancer, Cancer
GRAIL, Inc.
Observational
14,633
Arizona, California, Florida, Louisiana, Massachusetts, Oregon, Pennsylvania, South Carolina
2021-08-23
Active, closed
Predictive Multimodal Signatures Associated With Response to Treatment and Prognosis of Patients With Stage IV Non-small Cell Lung Cancer
NCT04994795Non-small Cell Lung Cancer Metastatic
Sophia Genetics SAS
Observational
4,000
Iowa, Massachusetts, Minnesota, New York, Utah, Wisconsin
2021-08-21
Active, closed
NKX019, Intravenous Allogeneic Chimeric Antigen Receptor Natural Killer Cells (CAR NK), in Adults With B-cell Cancers
NCT05020678Lymphoma, Non-Hodgkin, B-cell Acute Lymphoblastic Leukemia, Large B-cell Lymphoma, Mantle Cell Lymphoma
Nkarta, Inc.
Phase 1
150
Colorado, Ohio
2021-08-20
Active, closed
Evaluate the Safety and Effectiveness of iSTAR Medical's MINIjectโ„ข Implant for Lowering Intraocular Pressure (IOP) in Subjects With Primary Open-angle Glaucoma.
NCT05024695Glaucoma
iSTAR Medical
Not applicable
975
Arizona, Arkansas, California, Colorado, Florida, Idaho, Illinois, Kansas
2021-08-19
Active, closed
Safety and Efficacy Study of Investigational Agents as Monotherapy or in Combination With Pembrolizumab (MK-3475) for the Treatment of Extensive-Stage Small Cell Lung Cancer (ES-SCLC) in Need of Second-Line Therapy (MK-3475-B98/KEYNOTE-B98)
NCT04938817Small Cell Lung Carcinoma
Merck Sharp & Dohme LLC
Phase 1/2
110
Arizona, Georgia, Indiana, Kentucky, Maryland, Nebraska, Ohio, Pennsylvania
2021-08-19
Active, closed
A Phase 3 Study Evaluating Efficacy and Safety of Lanifibranor Followed by an Active Treatment Extension in Adult Patients With (NASH) and Fibrosis Stages F2 and F3 ( NATiV3 )
NCT04849728NASH - Nonalcoholic Steatohepatitis
Inventiva Pharma
Phase 3
1,000
Alabama, Arizona, Arkansas, California, Colorado, Connecticut, Florida, Georgia
2021-08-19
Active, closed
A Study of Bortezomib, Lenalidomide and Dexamethasone (VRd) Followed by Cilta-cel, a CAR-T Therapy Directed Against BCMA Versus VRd Followed by Lenalidomide and Dexamethasone (Rd) Therapy in Participants With Newly Diagnosed Multiple Myeloma for Whom ASCT is Not Planned as Initial Therapy
NCT04923893Multiple Myeloma
Janssen Research & Development, LLC
Phase 3
743
California, Connecticut, Florida, Iowa, Kentucky, Maryland, Massachusetts, Michigan
2021-08-19
Active, closed
STOP Persistent AF PAS
NCT05005949Persistent Atrial Fibrillation
Medtronic Cardiac Ablation Solutions
Observational
400
Connecticut, Florida, Illinois, Michigan, Ohio, Texas
2021-08-19
Active, closed
Pembrolizumab Plus Lenvatinib in Combination With Belzutifan in Solid Tumors (MK-6482-016)
NCT04976634Neoplasm Malignant
Merck Sharp & Dohme LLC
Phase 2
730
Arizona, California, Connecticut, District of Columbia, Florida, Maryland, Michigan, New York
2021-08-18
Active, closed
Study of Denikitug (GS-1811) Given Alone or With Zimberelimab in Adults With Advanced Solid Tumors
NCT05007782Advanced Solid Tumor
Gilead Sciences
Phase 1
304
California, Connecticut, Massachusetts, Tennessee, Texas, Wisconsin
2021-08-18
Active, closed
Long-Term Follow-up of Subjects Who Were Treated With ST-920
NCT05039866Fabry Disease, Fabry Disease, Cardiac Variant
Sangamo Therapeutics
Observational
32
California, Florida, Georgia, Iowa, Minnesota, New York, Ohio, Virginia
2021-08-16
Active, closed
A Study of Penpulimab (AK105) in the First-line Treatment of Recurrent or Metastatic Nasopharyngeal Carcinoma
NCT04974398Nasopharyngeal Carcinoma
Akeso
Phase 3
296
California, Georgia, Michigan, New York
2021-08-16
By invitation
Selatogrel Outcome Study in Suspected Acute Myocardial Infarction
NCT04957719Acute Myocardial Infarction
Viatris Innovation GmbH
Phase 3
25,000
Alabama, Arizona, California, Colorado, Delaware, District of Columbia, Florida, Georgia
2021-08-14
By invitation
A Study Evaluating Oral Eluxadoline Administered to Pediatric Participants With Irritable Bowel Syndrome With Diarrhea (IBS-D)
NCT04880876Irritable Bowel Syndrome
AbbVie
Phase 3
124
California, Florida, Georgia, Oklahoma, Pennsylvania
2021-08-13
Recruiting
Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases
NCT05003986Focal Segmental Glomerulosclerosis, Minimal Change Disease, Immunoglobulin A Nephropathy, IgA Vasculitis
Travere Therapeutics, Inc.
Phase 2
67
California, Delaware, Florida, Iowa, Massachusetts, Michigan, Minnesota, Missouri
2021-08-12
Active, closed
Evaluation of Oral Tofacitinib in Children Aged 2 to 17 Years Old Suffering From Moderate to Severe Ulcerative Colitis
NCT04624230Ulcerative Colitis
Pfizer
Phase 3
118
California, Connecticut, Florida, Georgia, Massachusetts, New York, Ohio, Pennsylvania
2021-08-12
Active, closed
Study Comparing Investigational Drug HBI-8000 + Nivolumab vs. Placebo + Nivolumab in Patients With Advanced Melanoma
NCT04674683Unresectable or Metastatic Melanoma, Progressive Brain Metastasis
HUYABIO International, LLC.
Phase 3
450
California, Florida, Indiana, Kentucky, Maryland, Missouri, Montana, North Carolina
2021-08-12
Recruiting
Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2ฮฑ Related Genetic Alterations (MK-6482-015)
NCT04924075Pheochromocytoma/Paraganglioma, Pancreatic Neuroendocrine Tumor, Von Hippel-Lindau Disease, Advanced Gastrointestinal Stromal Tumor
Merck Sharp & Dohme LLC
Phase 2
355
California, Illinois, Iowa, Maryland, Massachusetts, Michigan, Missouri, New York
2021-08-12
Active, closed
Study Assessing Long-teRm Outcomes of dupiluMAb (DUPIXENTยฎ) Treatment in Adult Patients With Chronic Rhinosinusitis With Nasal Polyposis (CRSwNP)
NCT04959448Chronic Rhinosinusitis With Nasal Polyposis
Regeneron Pharmaceuticals
Observational
717
Alabama, Arizona, California, Florida, Georgia, Idaho, Illinois, Indiana
2021-08-12
Active, closed
A Study to Investigate the Safety, Tolerability, and Processing by the Body of Intravenous and Subcutaneous RO7121932 Administration in Participants With Multiple Sclerosis
NCT05704361Multiple Sclerosis
Hoffmann-La Roche
Phase 1
119
California, Connecticut
2021-08-11
Recruiting
64Cu-SAR-bisPSMA and 67Cu-SAR-bisPSMA for Identification and Treatment of PSMA-expressing Metastatic Castrate Resistant Prostate Cancer (SECuRE)
NCT04868604Prostatic Neoplasms, Castration-Resistant
Clarity Pharmaceuticals Ltd
Phase 1/2
54
California, Louisiana, Michigan, Minnesota, Missouri, Nebraska, New York
2021-08-11
Recruiting
Combination of Intranasal Scopolamine and Sensory Augmentation to Mitigate G-transition Induced Motion Sickness and Enhance Sensorimotor Performance
NCT05852730Motion Sickness, Space, Motion Simulation, Parabolic Flight
Repurposed Therapeutics, Inc.
Phase 2
80
Texas
2021-08-10
Active, closed
Extension Study to Evaluate Safety and Tolerability of Oral Dersimelagon (MT-7117) in Subjects With Erythropoietic Protoporphyria (EPP) or X-Linked Protoporphyria (XLP)
NCT05005975EPP, XLP
Tanabe Pharma America, Inc.
Phase 3
286
California, Florida, Massachusetts, Michigan, Missouri, New York, North Carolina, Ohio
2021-08-10
Active, closed
US IDE Study of the Contour NEurovasCular Systemโ„ข for IntraCranial Aneurysm Repair
NCT04852783Aneurysm, Intracranial
Cerus Endovascular, Inc.
Phase 4
250
Colorado, Florida, Illinois, Kansas, Massachusetts, New York, North Carolina, Pennsylvania
2021-08-06
Recruiting
Phase 1a and Phase 2 Study for Safety, Preliminary Efficacy, PK and PD of ST-067
NCT04787042Cancer, Solid Tumor, Melanoma, Renal Cell Carcinoma
Simcha IL-18, Inc.
Phase 1/2
316
Arizona, Colorado, Connecticut, Florida, Massachusetts, New York
2021-08-06
Active, closed
Treatment Combination of Durvalumab, Tremelimumab and Enfortumab Vedotin or Durvalumab and Enfortumab Vedotin in Patients With Muscle Invasive Bladder Cancer Ineligible to Cisplatin or Who Refuse Cisplatin
NCT04960709Muscle Invasive Bladder Cancer
AstraZeneca
Phase 3
712
California, Connecticut, District of Columbia, Florida, Idaho, Illinois, Indiana, Iowa
2021-08-05
Active, closed
Evaluating the Clinical Effectiveness of a Patient-specific Silicone Stent
NCT05050591Pulmonary Disease, Chronic Obstructive
VisionAir Solutions
Not applicable
20
Minnesota, Ohio
2021-08-05
Active, closed
Study of Pembrolizumab (MK-3475) Subcutaneous (SC) Versus Pembrolizumab Intravenous (IV) Administered With Platinum Doublet Chemotherapy in Participants With Metastatic Squamous or Nonsquamous Non-Small Cell Lung Cancer (NSCLC) (MK-3475-A86)
NCT04956692Non-Small Cell Lung Cancer
Merck Sharp & Dohme LLC
Phase 3
531
Arkansas, California, Florida, Indiana, Kentucky, Missouri, Montana, New York
2021-08-05
By invitation
IT Matters: The Erectile Restoration Registry
NCT04200937Erectile Dysfunction
Boston Scientific Corporation
Observational
450
California, Florida, Illinois, Indiana, Louisiana, Missouri, North Carolina, Ohio
2021-08-05
Recruiting
A Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid Tumors
NCT04913285Solid Tumor, Adult, Non-small Cell Lung Cancer, Melanoma
Pierre Fabre Medicament
Phase 1
400
California, Colorado, Florida, Minnesota, New Jersey, New York, Ohio, Tennessee
2021-08-04
Active, closed
Study to Evaluate the Pharmacokinetics, Efficacy, Tolerability, and Safety of Subcutaneous Human Immunoglobulin (Newnorm) in Patients With Primary Immunodeficiency Diseases
NCT04640142Primary Immune Deficiency
Octapharma
Phase 3
50
California, Colorado, Florida, Illinois, Kansas, Kentucky, Maryland, Missouri
2021-08-04
Active, closed
Ultrasound-facilitated, Catheter-directed, Thrombolysis in Intermediate-high Risk Pulmonary Embolism
NCT04790370Pulmonary Embolism
Boston Scientific Corporation
Phase 4
544
Alabama, California, Delaware, Georgia, Indiana, Kentucky, Maryland, Massachusetts
2021-08-02
Recruiting
GI-101/GI-101A as a Single Agent or in Combination With Pembrolizumab or Lenvatinib in Advanced Solid Tumors
NCT04977453Advanced Solid Tumor, Metastatic Solid Tumor, Cervical Cancer, Urothelial Carcinoma
GI Innovation, Inc.
Phase 1/2
317
New York, North Carolina
2021-08-02
Active, closed
A Phase 3 Study to Evaluate the Safety and Tolerability of L606 in Subjects With PAH or PH-ILD
NCT04691154Pulmonary Arterial Hypertension, Pulmonary Hypertension Due to Lung Diseases
Liquidia Technologies, Inc.
Phase 3
28
Arizona, California, Florida, New York, Ohio, Oregon, Texas
2021-08-01
Recruiting
Reducing Pregnancy Risks: The Mastery Lifestyle Intervention
NCT05012072Mental Health Wellness 1, Preterm Birth
Microgen LLC
Not applicable
238
Texas
2021-08-01
Active, closed
A Novel Computer-Based Functional Skills Assessment and Training Program
NCT04679441Mild Cognitive Impairment, Healthy Aging
i-Function, Inc.
Phase 2
180
Florida, New York
2021-08-01
Recruiting
RAPA-201 Therapy of Solid Tumors
NCT05144698Solid Tumor, Small Cell and Non-small Cell Lung Cancer, Head and Neck Cancer, Squamous Cell Carcinoma of Oral Cavity
Rapa Therapeutics LLC
Phase 1/2
37
New Jersey
2021-08-01
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Priya Life Science (2026). Clinical trial register: industry-sponsored studies with a US investigative site. Derived from ClinicalTrials.gov. Retrieved 22 September 2026. https://priyalifescience.com/clinical-trials-usa?page=76

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Listing here is informational and not medical advice; eligibility is determined by each study team. Compare pay for the teams running these studies in the US Pharma Salary Guide, see who's behind them in the US Company Directory, or track approvals on the FDA Approvals Tracker. For Irish, UK and EU sites, see the Ireland, UK and EU registers.