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Clinical trial register · United States · industry-sponsored

Heart Failure Trials in the USA, 2026

Every industry-sponsored study on the ClinicalTrials.gov registry that lists a US site and is open, about to open, active-but-closed, or enrolling by invitation. This deliberately excludes academic and other non-industry sponsors — the full US registry across all sponsors runs to over 22,000 recruiting studies alone.

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Source: ClinicalTrials.gov. Complete coverage of the industry-sponsored slice — all 9118 matching records are in this view (non-industry sponsors are out of scope by design, not truncated). Synced 06 Oct 2026, 03:16 UTC
9118
Studies in scope
industry-sponsored, all four open statuses
4945
Recruiting now
open to new participants
2189
Lead sponsors
across recruiting studies
Top states
Arizona 4 Florida 4 California 3 Georgia 2 Indiana 2
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Recruitment status
Phase
Target enrolment
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Heart Failure trials in the USA

4 of 9118 studies
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Status
Study
Lead sponsor
Phase
Enrol
US states
Start
Recruiting
CCM OPEN HF Registry
NCT07112924Heart Failure
Impulse Dynamics
Observational
5,500
Arizona, Florida, Kansas, Massachusetts, Michigan, Minnesota, Missouri, New Hampshire
2025-11-01
Active, closed
Assessment of Combined CCM and ICD Device in HFrEF
NCT05855135Heart Failure, Heart Failure With Reduced Ejection Fraction, Implantable Defibrillator User, CCM Therapy
Impulse Dynamics
Not applicable
300
Arizona, California, Connecticut, Florida, Iowa, Kansas, Kentucky, Massachusetts
2023-05-17
Recruiting
Assessment of CCM in HF With Higher Ejection Fraction
NCT05064709Heart Failure, Heart Failure With Preserved Ejection Fraction, Heart Failure With Mid Range Ejection Fraction, Heart Failure With Moderately Reduced Ejection Fraction
Impulse Dynamics
Not applicable
1,500
Alabama, Arizona, California, Connecticut, Florida, Georgia, Indiana, Iowa
2022-02-03
Active, closed
Post Approval Study (PAS) of the OPTIMIZER Smart and CCM Therapy
NCT03970343Heart Failure
Impulse Dynamics
Observational
620
Arizona, California, Colorado, District of Columbia, Florida, Georgia, Illinois, Indiana
2020-01-21
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Cite this view

Priya Life Science (2026). Clinical trial register: industry-sponsored studies with a US investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 6 October 2026. https://priyalifescience.com/clinical-trials-usa/condition/heart-failure

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About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every industry-sponsored study on the registry that lists at least one investigative site in the US and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 9,118 studies in total at the last sync on 06 Oct 2026, 03:16 UTC. Academic and other non-industry sponsors are out of scope by design. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 4 of those studies listing the condition Heart Failure that also match the filters currently applied.

How many Heart Failure trials are recruiting in the US?

2 of the 4 studies on this page are recruiting new participants as of the 06 Oct 2026, 03:16 UTC sync. A further 0 have not yet opened recruitment, 2 are active but closed to new participants, and 0 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (Heart Failure), 4 studies
PhaseStudiesRecruitingShare
Not applicable2150%
Observational2150%

Most active sponsors

Lead sponsors with the most studies (Heart Failure)
Lead sponsorStudiesRecruiting
Impulse Dynamics42

Top states

Top states (Heart Failure), by number of studies with a site there
StateStudies
Arizona4
Florida4
California3
Connecticut2
Georgia2
Indiana2
Iowa2
Kansas2
Massachusetts2
Alabama1
Listing here is informational and not medical advice; eligibility is determined by each study team. Compare pay for the teams running these studies in the US Pharma Salary Guide, see who's behind them in the US Company Directory, or track approvals on the FDA Approvals Tracker. For Irish, UK and EU sites, see the Ireland, UK and EU registers.