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Trackers› Clinical trials› Illinois
Clinical trial register · United States · industry-sponsored

Clinical Trials in Illinois, 2026

Every industry-sponsored study on the ClinicalTrials.gov registry that lists a US site and is open, about to open, active-but-closed, or enrolling by invitation. This deliberately excludes academic and other non-industry sponsors โ€” the full US registry across all sponsors runs to over 22,000 recruiting studies alone.

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Source: ClinicalTrials.gov. Complete coverage of the industry-sponsored slice โ€” all 9119 matching records are in this view (non-industry sponsors are out of scope by design, not truncated). Synced 25 Sep 2026, 03:16 UTC
9119
Studies in scope
industry-sponsored, all four open statuses
4952
Recruiting now
open to new participants
2205
Lead sponsors
across recruiting studies
Top states
California 5301 Florida 4401 Illinois 2480 Georgia 2350 Arizona 2233
Narrow the registerReset
Recruitment status
Phase
Lead sponsor
AstraZeneca110 AbbVie101 Eli Lilly and Company71 Merck Sharp & Dohme LLC63 Novartis Pharmaceuticals60
State
California5301 Florida4401 Illinois2480 Georgia2350 Arizona2233
All 51 states
Target enrolment
to

Trials with a site in Illinois

2480 of 9119 studies
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Status
Study
Lead sponsor
Phase
Enrol
US states
Start
Recruiting
A Long-term, Post-marketing Safety Study of Palynziq in Patients With PKU (PALace)
NCT05813678Phenylketonuria (PKU)
DrugPegvaliase
BioMarin Pharmaceutical
Observational
450
Colorado, Georgia, Illinois, Indiana, Louisiana, Massachusetts, Oregon, Pennsylvania
2022-06-06
Recruiting
Study of ORIC-944 in Patients With Metastatic Prostate Cancer
NCT05413421Metastatic Prostate Cancer
ORIC Pharmaceuticals
Phase 1
275
Colorado, Florida, Illinois, Indiana, Maryland, Michigan, Minnesota, New York
2022-06-01
Active, closed
STAND - Study of the AGN1 LOEP SV Kit Compared to PMMA in Patients With Vertebral Compression Fractures
NCT04835428Vertebral Compression Fracture, Compression Fracture, Vertebral Compression
AgNovos Healthcare, LLC
Not applicable
408
Alabama, Arizona, Florida, Illinois, Kansas, Louisiana, Massachusetts, New York
2022-05-31
Recruiting
A Study of the Efficacy and Safety of DMX-200 in Patients With FSGS Who Are Receiving an ARB
NCT05183646FSGS
DrugDMX-200
Dimerix Bioscience Pty Ltd
Phase 3
286
Alabama, Arizona, California, Colorado, Florida, Georgia, Idaho, Illinois
2022-05-30
Active, closed
Study of Sacituzumab Govitecan Combinations in First-line Treatment of Participants With Advanced or Metastatic Non-Small-Cell Lung Cancer (NSCLC)
NCT05186974Non-small Cell Lung Cancer
DrugsSacituzumab Govitecan·Cisplatin·Carboplatin·Pembrolizumab
Gilead Sciences
Phase 2
193
Alaska, California, Colorado, District of Columbia, Florida, Georgia, Illinois, Kansas
2022-05-30
Recruiting
A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis
NCT05076175Colitis, Ulcerative
DrugOzanimod
Bristol-Myers Squibb
Phase 2/3
120
Arizona, California, Connecticut, District of Columbia, Florida, Georgia, Illinois, Indiana
2022-05-30
Active, closed
PERSEVERE- A Trial to Evaluate AMDS in Acute DeBakey Type I Dissection
NCT05174767Acute Aortic Dissection
Artivion Inc.
Not applicable
115
Alabama, California, Colorado, Connecticut, Florida, Georgia, Illinois, Massachusetts
2022-05-27
Active, closed
An Observational Study of the Progression of Intermediate Age-Related Macular Degeneration
NCT05300724Age-Related Macular Degeneration
Genentech, Inc.
Observational
400
Arkansas, California, Colorado, Florida, Georgia, Illinois, Indiana, Iowa
2022-05-27
By invitation
NuVasiveยฎ ACP System Study
NCT05066711Cervical Spondylosis, Cervical Radiculopathy, Cervical Myelopathy, Cervical Disc Disease
NuVasive
Observational
75
Illinois, Missouri, North Carolina
2022-05-22
Recruiting
SELUTION4BTK Trial
NCT05055297Peripheral Arterial Disease, Chronic Limb-Threatening Ischemia Nos of Native Arteries of Extremities
M.A. Med Alliance S.A.
Not applicable
376
Arizona, Arkansas, California, Colorado, Connecticut, Florida, Georgia, Illinois
2022-05-19
Active, closed
The AUDACITY Study (AllUrion Device in Adults With Clinical ObesITY)
NCT05368259Obesity
Allurion Technologies
Not applicable
1,000
Arizona, California, Colorado, Florida, Illinois, Indiana, Massachusetts, Missouri
2022-05-12
Active, closed
ALTERRA Post-Approval Study
NCT05378386Pulmonary Valve Insufficiency, Complex Congenital Heart Defect, Tetralogy of Fallot, Pulmonary Regurgitation
Edwards Lifesciences
Observational
150
Alabama, Arkansas, California, Colorado, Florida, Illinois, Massachusetts, Missouri
2022-05-12
Recruiting
REMASTer: REcurrent Brain Metastases After SRS Trial
NCT05124912Brain Metastases, Radiation Necrosis, Recurrent Tumor, Recurrent Metastases
Monteris Medical
Not applicable
261
California, Illinois, Maryland, Missouri, North Carolina, Ohio, Wisconsin
2022-05-10
Active, closed
Comparing PFO Outcomes of the Occlutech Flex II PFO Occluder to Standard of Care PFO Occlusion
NCT05069558Stroke, Patent Foramen Ovale, PFO
Occlutech International AB
Not applicable
450
Arizona, California, Colorado, District of Columbia, Illinois, Kentucky, Maine, Massachusetts
2022-05-09
Recruiting
Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.
NCT04771572Non Hodgkin Lymphoma, Richter Transformation, Multiple Myeloma, T-cell-prolymphocytic Leukemia
Newave Pharmaceutical Inc
Phase 1
100
Illinois, Massachusetts, North Carolina, Ohio, Texas, Utah
2022-05-08
Active, closed
P-BCMA-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With Multiple Myeloma
NCT04960579Multiple Myeloma
DrugsRimiducid·Methotrexate
Poseida Therapeutics, Inc.
Phase 1
275
Arizona, California, Georgia, Illinois, Iowa, Kansas, Maryland, Michigan
2022-05-05
Active, closed
RADIANCE Continued Access Protocol
NCT05017935Hypertension, Hypertension, Resistant to Conventional Therapy, Vascular Diseases, Cardiovascular Diseases
ReCor Medical, Inc.
Not applicable
300
California, Connecticut, Florida, Georgia, Illinois, Indiana, Iowa, Louisiana
2022-05-04
Recruiting
A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2
NCT04879329Urothelial Carcinoma
DrugsDisitamab Vedotin·Pembrolizumab
Seagen, a wholly owned subsidiary of Pfizer
Phase 2
372
Arizona, California, District of Columbia, Florida, Georgia, Illinois, Massachusetts, Michigan
2022-05-03
Active, closed
A Study to Evaluate the Effect of Venglustat Tablets on Left Ventricular Mass Index in Male and Female Adult Participants With Fabry Disease
NCT05280548Fabry Disease
DrugsMigalastat·Venglustat
Sanofi
Phase 3
104
Alabama, California, Georgia, Illinois, New York, Texas, Utah, Virginia
2022-05-03
Active, closed
A Rollover Study to Evaluate the Long-Term Safety and Efficacy of Ocrelizumab In Patients With Multiple Sclerosis
NCT05269004Multiple Sclerosis
DrugOcrelizumab
Hoffmann-La Roche
Phase 3
1,300
Arizona, California, Colorado, Florida, Georgia, Illinois, Indiana, Kansas
2022-05-03
Active, closed
A Study to Assess Long-term Outcomes of Myocarditis Following Administration of COVID-19 mRNA Vaccine (SPIKEVAX)
NCT06189053Myocarditis
ModernaTX, Inc.
Observational
1,500
Illinois
2022-04-30
Recruiting
Cephea Early Feasibility Study
NCT05061004Mitral Regurgitation
Abbott Medical Devices
Not applicable
90
Arizona, California, Georgia, Illinois, Kansas, Michigan, Minnesota, New York
2022-04-28
Recruiting
A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Thalamotomy for the Treatment of Medication-Refractory Tremor Dominant Idiopathic Parkinson's Disease
NCT04991831Tremor Associated With Tremor Dominant Parkinson's Disease
InSightec
Observational
50
Florida, Illinois, Massachusetts, New York, North Carolina, Ohio
2022-04-28
Active, closed
Use of the Impella BTRโ„ข in Patients With Heart Failure: An Early Feasibility Study
NCT05291884Heart Failure, Acute Decompensated Heart Failure
Abiomed Inc.
Not applicable
10
Georgia, Illinois, Massachusetts, New Jersey, Ohio
2022-04-20
Recruiting
Use of CereGate Therapy for Freezing of Gait in PD
NCT05292794Parkinson Disease, Freezing of Gait, Deep Brain Stimulation
CereGate Inc.
Not applicable
41
California, Colorado, Florida, Illinois, North Carolina, Tennessee, Washington
2022-04-18
Recruiting
(Peak) A Phase 3 Randomized Trial of CGT9486+Sunitinib vs. Sunitinib in Subjects With Gastrointestinal Stromal Tumors
NCT05208047Advanced Gastrointestinal Stromal Tumors, Metastatic Cancer
DrugsBezuclastinib·Sunitinib·Midazolam
Cogent Biosciences, Inc.
Phase 3
482
Alabama, Arizona, California, Colorado, District of Columbia, Florida, Illinois, Iowa
2022-04-14
Recruiting
Neoadjuvant and Adjuvant Treatment in Resectable Non-small Cell Lung Cancer
NCT05061550Non-small Cell Lung Cancer
DrugsAZD0171·Pemetrexed/Cisplatin·Pemetrexed/Carboplatin·Carboplatin, paclitaxel
AstraZeneca
Phase 2
630
Arkansas, California, Connecticut, Florida, Georgia, Illinois, Maryland, Massachusetts
2022-04-14
Recruiting
A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies
NCT05131022Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL), Diffuse Large B Cell Lymphoma (DLBCL), Follicular Lymphoma (FL)
DrugBexobrutideg
Nurix Therapeutics, Inc.
Phase 1
572
California, Colorado, Connecticut, Florida, Georgia, Illinois, Maryland, New York
2022-04-13
Active, closed
Phase 1/2 Study of Avutometinib (VS-6766) + Sotorasib With or Without Defactinib in KRAS G12C NSCLC Patients
NCT05074810Non Small Cell Lung Cancer, KRAS Activating Mutation
Verastem, Inc.
Phase 1/2
153
Colorado, District of Columbia, Illinois, Maryland, Massachusetts, Michigan, Minnesota, Missouri
2022-04-12
Active, closed
Study of Erdafitinib Intravesical Delivery System for Localized Bladder Cancer
NCT05316155Non-Muscle Invasive Bladder Neoplasms
Janssen Research & Development, LLC
Phase 1/2
235
Alabama, California, Colorado, Florida, Illinois, Indiana, Kentucky, Louisiana
2022-04-11
Active, closed
CASCADE-LUNG: Cancer Screening Assay Using DELFI; A Clinical Validation Study in Lung
NCT05306288Lung Cancer
Delfi Diagnostics Inc.
Observational
11,935
Alabama, California, Colorado, Connecticut, Florida, Georgia, Illinois, Kentucky
2022-04-07
By invitation
Long-Term Follow-Up Study of RGX-314 Administered in the Suprachoroidal Space for Participants With and Without Diabetic Retinopathy
NCT05296447Diabetic Retinopathy, DR
AbbVie
Phase 2
100
Arizona, California, Georgia, Illinois, Maryland, Massachusetts, Nevada, New Jersey
2022-04-04
Active, closed
A Phase 3 Study of Rusfertide in Patients With Polycythemia Vera
NCT05210790Polycythemia Vera
Protagonist Therapeutics, Inc.
Phase 3
293
Alabama, Arizona, California, Colorado, Connecticut, Florida, Illinois, Indiana
2022-04-01
Active, closed
Phase 1/2 Study of Silevertinib (BDTX-1535) in Patients With Glioblastoma or Non-Small Cell Lung Cancer With EGFR Mutations
NCT05256290Non-Small Cell Lung Cancer, Advanced Non-Small Cell Squamous Lung Cancer, Metastatic Lung Non-Small Cell Carcinoma, Metastatic Lung Cancer
Black Diamond Therapeutics, Inc.
Phase 1/2
200
Alabama, Arizona, California, District of Columbia, Florida, Hawaii, Illinois, Kansas
2022-03-31
Active, closed
Olorofim Aspergillus Infection Study
NCT05101187Invasive Aspergillosis
F2G Biotech GmbH
Phase 3
225
Alabama, California, Florida, Georgia, Illinois, Kansas, Maryland, Massachusetts
2022-03-31
Recruiting
4D-710 in Adult Patients With Cystic Fibrosis
NCT05248230Cystic Fibrosis Lung
4D Molecular Therapeutics
Phase 2
30
Alabama, Arizona, California, Colorado, Florida, Illinois, Kansas, Maryland
2022-03-29
Active, closed
Study With Elranatamab Versus Lenalidomide in Patients With Newly Diagnosed Multiple Myeloma After Transplant
NCT05317416Multiple Myeloma
DrugsElranatamab·Lenalidomide
Pfizer
Phase 3
854
Arizona, California, District of Columbia, Florida, Georgia, Illinois, Kansas, Michigan
2022-03-25
Recruiting
A Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
NCT04928846Non Small Cell Lung Cancer
DrugsTelisotuzumab vedotin·Paclitaxel
AbbVie
Phase 3
768
Alabama, Arizona, California, Florida, Georgia, Hawaii, Illinois, Indiana
2022-03-25
Active, closed
A Research Study on How Well Concizumab Works for You if You Have Haemophilia A or B With or Without Inhibitors
NCT05135559Haemophilia A and B With and Without Inhibitors
DrugConcizumab
Novo Nordisk A/S
Phase 3
153
California, Colorado, Florida, Georgia, Illinois, Indiana, Louisiana, Missouri
2022-03-24
Active, closed
Remote Optimization, Adjustment and Measurement for Deep Brain Stimulation
NCT05269862Parkinson Disease
Abbott Medical Devices
Not applicable
100
Arizona, California, Florida, Illinois, Indiana, Massachusetts, New Hampshire, Ohio
2022-03-24
Recruiting
OssDsignยฎ Spine Registry Study ("Propel")
NCT05329129Degenerative Disc Disease, Spinal Stenosis
OssDsign
Observational
450
California, Connecticut, Florida, Georgia, Illinois, Kentucky, Maryland, Minnesota
2022-03-23
Active, closed
Non-Guided vs. Guided Surgery to Immediately Loaded PrimeTaper Implants in Partially Edentulous Patients
NCT05264545Partially Edentulous Maxilla or Mandible
McGuire Institute
Not applicable
100
Colorado, Illinois, Nebraska, Tennessee, Texas, Washington, Wisconsin
2022-03-22
Active, closed
Abemaciclib (LY2835219) Plus Fulvestrant Compared to Placebo Plus Fulvestrant in Previously Treated Breast Cancer
NCT05169567Breast Neoplasm, Neoplasm Metastasis
DrugsAbemaciclib·Fulvestrant
Eli Lilly and Company
Phase 3
368
Arizona, Arkansas, California, Colorado, Florida, Georgia, Hawaii, Illinois
2022-03-11
Active, closed
A Study of Zanubrutinib Plus Anti-CD20 Versus Lenalidomide Plus Rituximab in Participants With Relapsed/Refractory Follicular or Marginal Zone Lymphoma
NCT05100862Relapsed/Refractory Follicular Lymphoma, Marginal Zone Lymphoma
DrugsZanubrutinib·Obinutuzumab·Lenalidomide·Rituximab
BeOne Medicines
Phase 3
799
California, Florida, Georgia, Illinois, Indiana, Iowa, Kansas, Kentucky
2022-03-10
Recruiting
Study of ORIC-114 in Patients With Advanced Solid Tumors Harboring an EGFR or HER2 Alteration
NCT05315700Solid Tumors
ORIC Pharmaceuticals
Phase 1/2
350
California, Connecticut, District of Columbia, Florida, Illinois, Massachusetts, Minnesota, New York
2022-03-10
Recruiting
A Long-term Study for Participants Previously Treated With Ciltacabtagene Autoleucel
NCT05201781Multiple Myeloma
DrugCilta-cel
Janssen Research & Development, LLC
Phase 4
295
Arizona, California, Florida, Georgia, Illinois, Indiana, Kansas, Massachusetts
2022-03-09
Active, closed
Ifinatamab Deruxtecan (I-DXd) in Subjects With Pretreated Extensive-Stage Small Cell Lung Cancer (ES-SCLC)
NCT05280470Extensive-stage Small-cell Lung Cancer
DrugIfinatamab Deruxtecan
Daiichi Sankyo
Phase 2
187
Arkansas, Florida, Illinois, Maryland, Massachusetts, Michigan, Missouri, New Jersey
2022-03-09
Recruiting
EPIC-Peds: A Study to Learn About the Study Medicine Called PF-07321332 (Nirmatrelvir)/Ritonavir in Patients Under 18 Years of Age With COVID-19 That Are Not Hospitalized But Are at Risk for Severe Disease
NCT05261139COVID-19
DrugRitonavir
Pfizer
Phase 3
160
Arizona, California, District of Columbia, Florida, Georgia, Illinois, Louisiana, Maryland
2022-03-07
Active, closed
A Study of Tucatinib or Placebo With Trastuzumab and Pertuzumab for Metastatic HER2+ Breast Cancer
NCT05132582HER2 Positive Breast Cancer
DrugsTucatinib·Pertuzumab·Trastuzumab
Seagen, a wholly owned subsidiary of Pfizer
Phase 3
654
Arizona, Arkansas, California, Florida, Georgia, Illinois, Kentucky, Maryland
2022-03-07
Recruiting
A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)
NCT04988555Leukemia, Myeloid, Acute, Leukemia, Lymphocytic, Acute, Multiple Myeloma, Myelodysplastic Syndromes
DrugsGilteritinib·Azacitidine·Venetoclax
Sumitomo Pharma America, Inc.
Phase 1/2
606
California, Colorado, District of Columbia, Florida, Illinois, Maryland, Massachusetts, New Jersey
2022-02-28
Recruiting
Efficacy and Safety Study of Rimegepant for the Preventative Treatment of Migraine in Pediatric Subjects
NCT05156398Migraine
DrugRimegepant
Pfizer
Phase 3
640
Arkansas, California, Colorado, District of Columbia, Florida, Georgia, Idaho, Illinois
2022-02-28
Active, closed
A Study to Investigate Faricimab Treatment Response in Treatment-Naive, Underrepresented Patients With Diabetic Macular Edema
NCT05224102Diabetic Macular Edema
DrugFaricimab
Genentech, Inc.
Phase 4
218
Arizona, California, Colorado, District of Columbia, Florida, Illinois, Maryland, Michigan
2022-02-28
Recruiting
Posaconazole (MK-5592) Intravenous and Oral in Children (<2 Years) With Invasive Fungal Infection (MK-5592-127)
NCT04665037Invasive Fungal Infection
DrugPosaconazole
Merck Sharp & Dohme LLC
Phase 2
40
California, Florida, Illinois, North Carolina, Texas
2022-02-22
Active, closed
A Global Study to Assess the Effects of Osimertinib in Participants With EGFRm Stage IA2-IA3 NSCLC Following Complete Tumour Resection
NCT05120349Non-Small Cell Lung Cancer
DrugOsimertinib
AstraZeneca
Phase 3
390
Alaska, California, Colorado, Delaware, Georgia, Illinois, Maryland, New Jersey
2022-02-21
Active, closed
Setrusumab vs Placebo for Osteogenesis Imperfecta
NCT05125809Osteogenesis Imperfecta
DrugSetrusumab
Ultragenyx Pharmaceutical Inc
Phase 2/3
183
Arkansas, California, Colorado, Connecticut, Delaware, District of Columbia, Florida, Illinois
2022-02-21
Active, closed
A Global Study to Assess the Effects of Durvalumab + Domvanalimab Following Concurrent Chemoradiation in Participants With Stage III Unresectable NSCLC
NCT05211895Non-Small Cell Lung Cancer
DrugsDomvanalimab·Durvalumab
AstraZeneca
Phase 3
791
Arizona, California, District of Columbia, Florida, Georgia, Illinois, Kentucky, Maryland
2022-02-18
Recruiting
A Study of Azenosertib (ZN-c3) in Subjects With Platinum-Resistant High-Grade Serous Ovarian, Fallopian Tube or Primary Peritoneal Cancer
NCT05128825High-Grade Serous Ovarian, Fallopian Tube or Primary Peritoneal Cancer
DrugAzenosertib
K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc
Phase 2
310
Alabama, Arizona, California, Colorado, Connecticut, Florida, Georgia, Illinois
2022-02-17
Active, closed
177Lu-PSMA-I&T for Metastatic Castration-Resistant Prostate Cancer
NCT05204927Metastasis From Malignant Tumor of Prostate
Curium US LLC
Phase 3
439
Arizona, California, Florida, Illinois, Maryland, Michigan, Minnesota, Missouri
2022-02-14
Active, closed
A Phase III Study of JR-141 in Patients With Mucopolysaccharidosis II (STARLIGHT)
NCT04573023Mucopolysaccharidosis II
DrugsIdursulfase·JR-141
JCR Pharmaceuticals Co., Ltd.
Phase 3
86
Arizona, California, Illinois, Minnesota, New York, North Carolina, Pennsylvania
2022-02-14
Active, closed
A Study of a Patient-Specific Neoantigen Vaccine in Combination With Immune Checkpoint Blockade for Patients With Metastatic Colorectal Cancer
NCT05141721Colorectal Neoplasms
DrugsFluoropyrimidine·Ipilimumab·Leucovorin·Atezolizumab
Seattle Project Corporation
Phase 2/3
700
Arizona, Arkansas, California, Colorado, Connecticut, Florida, Illinois, Indiana
2022-02-12
Recruiting
AN INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY TO ASSESS THE PERFORMANCE OF THE CORDIO HEARO SYSTEM
NCT06378632Heart Failure
Cordio Medical
Observational
500
Alabama, California, Florida, Georgia, Illinois, Kansas, Kentucky, Louisiana
2022-02-11
Active, closed
A Study Evaluating the Efficacy and Safety of Mitapivat (AG-348) in Participants With Sickle Cell Disease (RISE UP)
NCT05031780Sickle Cell Disease
DrugMitapivat
Agios Pharmaceuticals, Inc.
Phase 2/3
286
California, Connecticut, District of Columbia, Florida, Illinois, Indiana, Louisiana, Maryland
2022-02-11
Recruiting
A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Crohn's Disease (CD)
NCT04779320Crohn's Disease (CD)
DrugVedolizumab
Takeda
Phase 3
120
Arizona, California, Florida, Georgia, Illinois, Indiana, Maryland, Massachusetts
2022-02-10
Active, closed
Long-term Assessment of the Safety and Performance of the NuVasive Simplify Disc
NCT05258435Cervical Disc Disease, Degenerative Disc Disease
NuVasive
Observational
131
California, Colorado, Florida, Illinois, Indiana, Louisiana, North Carolina, Texas
2022-02-09
Recruiting
InSpace Accelerated Rehabilitation Study
NCT05329584Rotator Cuff Tears
Stryker Endoscopy
Not applicable
160
Arizona, Arkansas, Colorado, Florida, Georgia, Illinois, Minnesota, New York
2022-02-07
Active, closed
A Global Study to Assess the Effects of Durvalumab With Oleclumab or Durvalumab With Monalizumab Following Concurrent Chemoradiation in Patients With Stage III Unresectable Non-Small Cell Lung Cancer
NCT05221840Non-Small Cell Lung Cancer
DrugsMonalizumab·Oleclumab·Durvalumab
AstraZeneca
Phase 3
1,051
California, Connecticut, Florida, Illinois, Indiana, Kentucky, Maryland, Michigan
2022-02-07
Active, closed
Insigniaโ„ข Hip Stem Outcomes Study
NCT05144191Hip Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis, Post-traumatic Osteoarthritis
Stryker Orthopaedics
Not applicable
313
Arizona, California, Illinois, Nevada, New York, North Carolina, Pennsylvania, Tennessee
2022-02-07
Active, closed
Cardiovascular Outcome Study to Evaluate the Effect of Obicetrapib in Patients With Cardiovascular Disease
NCT05202509Atherosclerotic Cardiovascular Disease
DrugObicetrapib
NewAmsterdam Pharma
Phase 3
9,541
Alabama, Arizona, Arkansas, California, Connecticut, Florida, Georgia, Illinois
2022-02-07
By invitation
A Study to Test the Safety and Tolerability of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures
NCT05076617Stereotypical Prolonged Seizures
DrugStaccato alprazolam
UCB Biopharma SRL
Phase 3
300
Arizona, Arkansas, California, District of Columbia, Florida, Hawaii, Idaho, Illinois
2022-02-03
Active, closed
Study of Pembrolizumab (MK-3475) Versus Chemotherapy in Mismatch Repair Deficient (dMMR) Advanced or Recurrent Endometrial Carcinoma (MK-3475-C93/KEYNOTE-C93/GOG-3064/ENGOT-en15)
NCT05173987Endometrial Neoplasms
DrugsTaxotere·Paraplatin·Taxol·Cisplatin
Merck Sharp & Dohme LLC
Phase 3
280
Arizona, California, Connecticut, Florida, Georgia, Illinois, Indiana, Kentucky
2022-02-03
Active, closed
Safety and Immunogenicity of CRV-101 Vaccine for the Prevention of Herpes Zoster in Adults Aged 50 Years and Older
NCT05304351Herpes Zoster, Shingles
DrugShingrix
Curevo Inc
Phase 2
1,516
Arizona, Florida, Illinois, Kansas, Kentucky, Nevada, Oklahoma, Tennessee
2022-02-02
Active, closed
A Study to Evaluate the Efficacy and Safety of Rozanolixizumab in Adult Participants With Myelin Oligodendrocyte Glycoprotein (MOG) Antibody-associated Disease (MOGAD)
NCT05063162Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease (MOGAD)
DrugRozanolixizumab
UCB Biopharma SRL
Phase 3
113
Arizona, California, Colorado, District of Columbia, Florida, Illinois, Maryland, Massachusetts
2022-02-02
Recruiting
A Phase 1/2a Study of DB-1303/BNT323 in Advanced/Metastatic Solid Tumors
NCT05150691HER2-positive Advanced Solid Tumor
DrugsRitonavir·DB-1303/BNT323·Itraconazole·Pertuzumab
DualityBio Inc.
Phase 1/2
796
California, District of Columbia, Florida, Georgia, Hawaii, Illinois, Louisiana, Maryland
2022-01-31
Recruiting
Study of STK-012 Alone and With Other Treatments in Patients With Advanced Lung Cancer and Other Cancers
NCT05098132Advanced Solid Tumor, Non Small Cell Lung Cancer, Untreated Advanced NSCLC, 1st Line NSCLC
DrugsPembrolizumab KEYTRUDA·Pemetrexed·Carboplatin
Synthekine
Phase 1/2
364
Arizona, California, Connecticut, District of Columbia, Georgia, Illinois, Maryland, Massachusetts
2022-01-25
Recruiting
Safety and Efficacy of Brilaroxazine (RP5063) in Schizophrenia
NCT05184335Schizophrenia
Reviva Pharmaceuticals
Phase 3
690
Arizona, Arkansas, California, Florida, Georgia, Illinois, Maryland, Massachusetts
2022-01-24
Active, closed
Progressive Myopia Treatment Evaluation for NaturalVue Multifocal Contact Lens Trial
NCT05159765Myopia
Visioneering Technologies, Inc
Not applicable
144
California, Illinois, New York, Texas
2022-01-22
Recruiting
A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003)
NCT05139017DLBCL, Diffuse Large B-Cell Lymphoma
DrugsRiabni·Ruxience·Granulocyte Colony-Stimulating Factor·Zilovertamab vedotin
Merck Sharp & Dohme LLC
Phase 2/3
290
Arizona, California, Florida, Illinois, Kentucky, Maryland, Massachusetts, Michigan
2022-01-14
Active, closed
Screening for High Frequency Malignant Disease
NCT05117840Lung Cancer
Guardant Health, Inc.
Observational
12,000
Alabama, Arkansas, California, Connecticut, District of Columbia, Florida, Georgia, Illinois
2022-01-13
Active, closed
Pivotal 2 Study of RGX-314 Gene Therapy in Participants With nAMD
NCT05407636AMD, nAMD, Wet Age-related Macular Degeneration, wAMD
DrugsEylea·Aflibercept
AbbVie
Phase 3
735
Arizona, California, Colorado, Connecticut, Florida, Georgia, Hawaii, Illinois
2022-01-13
Active, closed
A Study to Investigate Safety and Tolerability of TransCon IL-2 ฮฒ/ฮณ Alone or in Combination With Pembrolizumab and/or TransCon TLR7/8 Agonist or Other Anticancer Therapies in Adult Participants With Locally Advanced or Metastatic Solid Tumor Malignancies
NCT05081609Advanced Solid Tumor, Locally Advanced Solid Tumor, Metastatic Solid Tumor, Platinum-resistant Ovarian Cancer
DrugsTrastuzumab emtansine·Trastuzumab·Pembrolizumab
Ascendis Pharma Oncology Division A/S
Phase 1/2
320
California, Illinois, Kentucky, Massachusetts, New Jersey, New York, North Carolina, Ohio
2022-01-11
Active, closed
Proact: A Study of REACT in Subjects With Type 2 Diabetes Mellitus and Chronic Kidney Disease
NCT05099770Type 2 Diabetes Mellitus, Chronic Kidney Diseases
Prokidney
Phase 3
685
Alabama, Arizona, California, Delaware, Florida, Georgia, Idaho, Illinois
2022-01-05
Recruiting
Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II
NCT05102019Refractory Angina
Shockwave Medical, Inc.
Not applicable
380
Arizona, California, Colorado, Connecticut, District of Columbia, Florida, Georgia, Illinois
2022-01-04
Recruiting
A Study of Zidesamtinib (NVL-520) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ROS1 Rearrangement (ARROS-1)
NCT05118789Locally Advanced Solid Tumor, Metastatic Solid Tumor
Nuvalent Inc.
Phase 1/2
359
California, Colorado, District of Columbia, Florida, Illinois, Massachusetts, Michigan, Missouri
2022-01-04
Active, closed
A Study of an Epstein-Barr Virus (EBV) Candidate Vaccine, mRNA-1189, in 10- to 30-Year-Old Healthy Adolescents and Adults
NCT05164094Epstein-Barr Virus Infection
DrugMRNA-1189
ModernaTX, Inc.
Phase 1/2
867
Alabama, California, Florida, Georgia, Idaho, Illinois, Indiana, Iowa
2021-12-28
Active, closed
HALOS: A Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of Multiple Ascending Doses of ION582 in Participants With Angelman Syndrome
NCT05127226Angelman Syndrome
DrugObudanersen
Ionis Pharmaceuticals, Inc.
Phase 1/2
71
California, Colorado, Illinois, Massachusetts, North Carolina, Texas
2021-12-22
Active, closed
Rho Kinase Inhibitor in Amyotrophic Lateral Sclerosis (REAL)
NCT05218668Amyotrophic Lateral Sclerosis
Woolsey Pharmaceuticals
Phase 2
40
Arizona, Colorado, Florida, Illinois, Kentucky, Missouri, New York
2021-12-22
Active, closed
INSPIRE Pipelineโ„ข Shield Post Approval Study
NCT05071963Intracranial Aneurysm
Medtronic Neurovascular Clinical Affairs
Observational
246
Alabama, Connecticut, Florida, Georgia, Illinois, Kentucky, Missouri, New York
2021-12-20
Active, closed
Study Assessing the Long-term Effect of Dupilumab on Prevention of Lung Function Decline in Adult Patients With Uncontrolled Moderate to Severe Asthma
NCT05097287Asthma
DrugDupilumab
Sanofi
Phase 4
1,339
Alabama, Arizona, California, Florida, Georgia, Illinois, Kentucky, Louisiana
2021-12-16
Active, closed
Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS) (REMODEL-1)
NCT05147220Relapsing Multiple Sclerosis
DrugsTeriflunomide·Remibrutinib
Novartis Pharmaceuticals
Phase 3
1,000
Arizona, Arkansas, California, Colorado, Delaware, District of Columbia, Florida, Illinois
2021-12-16
Active, closed
CORRECT Study of Minimal Residual Disease Detection in Colorectal Cancer
NCT05210283Colorectal Cancer
Exact Sciences Corporation
Observational
1,017
California, Florida, Illinois, Iowa, Kansas, Maryland, Minnesota, Missouri
2021-12-15
By invitation
Long-Term Follow-Up Study After Gene-Modified Cell Treatment in Kite Studies
NCT05041309Solid and Hematological Malignancies, Autoimmune Diseases
DrugsKITE-197·KITE-753·KITE-363·Axicabtagene Ciloleucel
Kite, A Gilead Company
Observational
1,500
Arizona, California, Colorado, District of Columbia, Florida, Illinois, Iowa, Kansas
2021-12-15
Active, closed
A Study to Test How Safe Pozelimab and Cemdisiran Combination Therapy and Cemdisiran Alone Are and How Well They Work in Adult Patients With Generalized Myasthenia Gravis
NCT05070858Generalized Myasthenia Gravis
DrugsCemdisiran·Pozelimab
Regeneron Pharmaceuticals
Phase 3
288
Arizona, California, Colorado, Florida, Illinois, Michigan, Ohio, Pennsylvania
2021-12-14
Recruiting
Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors
NCT05176483Renal Cell Carcinoma (RCC), Metastatic Castration-Resistant Prostate Cancer (mCRPC), Urothelial Carcinoma (UC), Solid Tumor
DrugsRelatlimab·Zanzalintinib·Ipilimumab·Prednisone
Exelixis
Phase 1
1,394
Arizona, California, Colorado, Connecticut, Delaware, Florida, Illinois, Indiana
2021-12-14
Recruiting
A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS)
NCT04853251Neovascular Age-related Macular Degeneration
DrugsLucentis·Ranibizumab
Genentech, Inc.
Phase 4
188
Arizona, California, Colorado, Connecticut, Florida, Georgia, Illinois, Iowa
2021-12-14
Active, closed
Pembrolizumab/Placebo Plus Paclitaxel With or Without Bevacizumab for Platinum-resistant Recurrent Ovarian Cancer (MK-3475-B96/KEYNOTE-B96/ENGOT-ov65).
NCT05116189Ovarian Cancer, Carcinoma, Ovarian Epithelial, Fallopian Tube Neoplasms
DrugsPembrolizumab·Bevacizumab·Paclitaxel
Merck Sharp & Dohme LLC
Phase 3
643
Arizona, California, Connecticut, Florida, Georgia, Illinois, Indiana, Kentucky
2021-12-13
Recruiting
4D-150 in Patients With Neovascular (Wet) Age-Related Macular Degeneration
NCT05197270Neovascular (Wet) Age-Related Macular Degeneration
DrugsAflibercept IVT·4D-150 IVT
4D Molecular Therapeutics
Phase 1/2
215
Arizona, California, Colorado, Florida, Illinois, Indiana, Maryland, Massachusetts
2021-12-09
Active, closed
PATHFINDER 2: A Multi-Cancer Early Detection Study
NCT05155605Early Detection of Cancer, Cancer
GRAIL, Inc.
Not applicable
35,883
California, Colorado, District of Columbia, Florida, Georgia, Illinois, Louisiana, Maryland
2021-12-08
Recruiting
First-in-Human Study of Mutant-selective PI3Kฮฑ Inhibitor, RLY-2608, as a Single Agent in Patients With Advanced Solid Tumors and in Combination With Endocrine Therapy +/- a CDK4/6 or CDK4 Inhibitor in Patients With Advanced Solid Tumors or Advanced Breast Cancer
NCT05216432PIK3CA Mutation, Solid Tumor, Adult, HER2-negative Breast Cancer, Breast Cancer
DrugsRLY-2608·PF-07220060·Ribociclib·Palbociclib
Relay Therapeutics, Inc.
Phase 1
930
Arizona, California, Colorado, Connecticut, Florida, Illinois, Indiana, Massachusetts
2021-12-08
Active, closed
Intraventricular Administration of Rhenium-186 NanoLiposome for Leptomeningeal Metastases
NCT05034497Leptomeningeal Metastasis
Drug186RNL
Cerenome
Phase 1
18
Illinois, New York, Ohio, Texas
2021-12-06
Active, closed
Tapinarof for the Treatment of Plaque Psoriasis in Pediatric Subjects
NCT05172726Plaque Psoriasis
DrugTapinarof
Organon and Co
Phase 3
58
Arkansas, California, Florida, Illinois, Indiana, Ohio, Oregon, Washington
2021-12-02
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Cite this view

Priya Life Science (2026). Clinical trial register: industry-sponsored studies with a US investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 25 September 2026. https://priyalifescience.com/clinical-trials-usa/state/illinois?page=19

Query this register directly
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About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every industry-sponsored study on the registry that lists at least one investigative site in the US and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 9,119 studies in total at the last sync on 25 Sep 2026, 03:16 UTC. Academic and other non-industry sponsors are out of scope by design. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 2,480 of those studies with a site in Illinois.

How many clinical trials are recruiting in Illinois?

1,263 of the 2,480 studies on this page are recruiting new participants as of the 25 Sep 2026, 03:16 UTC sync. A further 37 have not yet opened recruitment, 1,117 are active but closed to new participants, and 63 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Listing here is informational and not medical advice; eligibility is determined by each study team. Compare pay for the teams running these studies in the US Pharma Salary Guide, see who's behind them in the US Company Directory, or track approvals on the FDA Approvals Tracker. For Irish, UK and EU sites, see the Ireland, UK and EU registers.