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Priya Life Science Clinical trial register
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Trackers› Clinical trials› Severe Asthma
Clinical trial register · United States · industry-sponsored

Severe Asthma Trials in the USA, 2026

Every industry-sponsored study on the ClinicalTrials.gov registry that lists a US site and is open, about to open, active-but-closed, or enrolling by invitation. This deliberately excludes academic and other non-industry sponsors — the full US registry across all sponsors runs to over 22,000 recruiting studies alone.

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Source: ClinicalTrials.gov. Complete coverage of the industry-sponsored slice — all 9107 matching records are in this view (non-industry sponsors are out of scope by design, not truncated). Synced 02 Oct 2026, 03:16 UTC
9107
Studies in scope
industry-sponsored, all four open statuses
4948
Recruiting now
open to new participants
2191
Lead sponsors
across recruiting studies
Top states
California 5 Florida 5 Michigan 3 Illinois 2 Missouri 2
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Recruitment status
Phase
Target enrolment
to

Severe Asthma trials in the USA

5 of 9107 studies
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Status
Study
Lead sponsor
Phase
Enrol
US states
Start
Recruiting
A Clinical Study to Evaluate the Efficacy and Safety of Frevecitinib (KN-002) in Patients With Severe Asthma
NCT07532265Severe Asthma
Kinaset Therapeutics Inc
Phase 2
512
California, Florida, Illinois, Missouri, North Carolina, Pennsylvania, South Carolina, Texas
2026-07-16
Recruiting
A Study to Investigate GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma (SOLAIRIA-2)
NCT07359846Severe Asthma
Generate Biomedicines
Phase 3
786
California, Florida, Massachusetts, Michigan, New York, Ohio, Oklahoma, South Carolina
2026-01-20
Recruiting
A Study to Investigate GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma (SOLAIRIA-1)
NCT07276724Severe Asthma
Generate Biomedicines
Phase 3
786
California, Colorado, Florida, Georgia, Illinois, Maryland, Michigan, Mississippi
2025-12-03
Active, closed
A Long-Term Safety and Efficacy Study of Verekitug (UPB-101) in Adult Participants With Severe Asthma (VALOUR)
NCT06966479Severe Asthma
Upstream Bio Inc.
Phase 2
396
California, Florida, Idaho, Maryland, Michigan, Nevada, New York, Ohio
2025-05-21
Active, closed
Open-label Study to Assess Reduction of Background Asthma Medication While Sustaining Asthma Control and Clinical Remission With Tezepelumab in Patients 12-80yrs With Severe Asthma.
NCT06473779Severe Asthma
AstraZeneca
Phase 3
326
California, Colorado, Florida, Massachusetts, Missouri, New Jersey, Oklahoma, Texas
2024-09-30
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1
Cite this view

Priya Life Science (2026). Clinical trial register: industry-sponsored studies with a US investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 2 October 2026. https://priyalifescience.com/clinical-trials-usa/condition/severe-asthma

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About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every industry-sponsored study on the registry that lists at least one investigative site in the US and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 9,107 studies in total at the last sync on 02 Oct 2026, 03:16 UTC. Academic and other non-industry sponsors are out of scope by design. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 5 of those studies listing the condition Severe Asthma.

How many Severe Asthma trials are recruiting in the US?

3 of the 5 studies on this page are recruiting new participants as of the 02 Oct 2026, 03:16 UTC sync. A further 0 have not yet opened recruitment, 2 are active but closed to new participants, and 0 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (Severe Asthma), 5 studies
PhaseStudiesRecruitingShare
Phase 33260%
Phase 22140%

Most active sponsors

Lead sponsors with the most studies (Severe Asthma)
Lead sponsorStudiesRecruiting
Generate Biomedicines22
AstraZeneca10
Kinaset Therapeutics Inc11
Upstream Bio Inc.10

Top states

Top states (Severe Asthma), by number of studies with a site there
StateStudies
California5
Florida5
Michigan3
Colorado2
Illinois2
Maryland2
Massachusetts2
Missouri2
New York2
Ohio2
Listing here is informational and not medical advice; eligibility is determined by each study team. Compare pay for the teams running these studies in the US Pharma Salary Guide, see who's behind them in the US Company Directory, or track approvals on the FDA Approvals Tracker. For Irish, UK and EU sites, see the Ireland, UK and EU registers.