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Clinical Trials in Turkey / NCT07866690
Starting soon Not applicable

Pain Neuroscience Education and Neuromuscular Exercise in Individuals With Chronic Low Back Pain and Central Sensitization

NCT07866690 · tracked via the Priya Life Science Turkey tracker
Sponsor
Izmir Katip Celebi University
Phase
Not applicable
Started
2026-10
Last updated
2026-10-08

Condition(s) studied

Low Back PainChronic Low Back PainCentral Sensitization

Investigational drug(s) / intervention(s)

Pain Neuroscience EducationNeuromuscular Exercise

Pain Neuroscience Education: Participants will receive pain neuroscience education (PNE) and neuromuscular exercise (NME) twice weekly for 8 weeks. Each session will last approximately 30-40 minutes.

Neuromuscular Exercise: Participants will receive neuromuscular exercise (NME) twice weekly for 8 weeks. Each session will last approximately 30-40 minutes.

Study summary

The goal of this randomized controlled study is to evaluate the effectiveness of pain neuroscience education (PNE) combined with neuromuscular exercises (NME) in individuals with chronic low back pain and central sensitization, and to compare the effects of this combined intervention with NME alone.

The main questions it aims to answer are:

* Does PNE combined with NME (PNE+NME) affect pain and functional outcomes in individuals with chronic low back pain and central sensitization?
* Does NME alone affect pain and functional outcomes in individuals with chronic low back pain and central sensitization?
* Does adding PNE to NME affect pain and functional outcomes compared with NME alone?

Researchers will evaluate changes in pain and functional outcomes from baseline to post-intervention in both the PNE+NME and NME groups. Changes in outcomes will then be compared between the two groups to determine whether adding PNE to NME affects pain and functional outcomes compared with NME alone.

Participants will:

* Be randomly assigned to either the PNE+NME group or the NME group.
* Participate in the assigned intervention for 8 weeks, with 2 sessions per week.
* Complete outcome assessments at baseline and after the 8-week intervention.

Eligibility

Sex
ALL
Min age
18 Years
Max age
60 Years
Healthy volunteers
No
Inclusion Criteria: * Age 18-60 years * Low back pain lasting for at least 3 months * Low back pain as the primary complaint * Central Sensitization Inventory (CSI) score ≥28 * Ability to read and write in Turkish * Willingness to participate in the study Exclusion Criteria: * History of spinal surgery * Presence of serious comorbidities (neurological, neuromuscular, cardiovascular, psychiatric conditions) * Presence of tumoral conditions * Presence of vestibular system disorders * Pregnancy * Having received physiotherapy within the previous 6 months

Primary outcome measure(s)

  • Pain intensity — At baseline and after the 8-week intervention
    Visual Analog Scale (VAS)

Trial sites (1)

FacilityCityRegionStatus
Izmir Katip Celebi University Izmir Turkey (Türkiye)

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07866690 on ClinicalTrials.gov ↗ ← All trials in Turkey