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Starting soon Not applicable

Effect of Prewarming Duration on Blood Flow After Colon Resection Surgery

NCT07857538 · tracked via the Priya Life Science Turkey tracker
Sponsor
Çiğdem Ünal Kantekin
Phase
Not applicable
Started
2026-10-15
Last updated
2026-10-05

Condition(s) studied

Perioperative Hypothermia

Investigational drug(s) / intervention(s)

Preoperative Forced-Air Warming

Preoperative Forced-Air Warming: Active warming using a forced-air warming system in the preoperative preparation area before general anesthesia. The upper and lower body are warmed for 10 or 30 minutes according to randomized group assignment. Device temperature settings follow manufacturer recommendations and institutional clinical standards.

Study summary

This study will examine whether warming patients before colon resection surgery improves blood flow in the fingers during early recovery from general anesthesia. It will also compare two warming durations. A total of 108 adults scheduled for elective colon resection surgery at Kayseri City Hospital will be assigned by chance to one of three groups: 10 minutes of warming before anesthesia, 30 minutes of warming before anesthesia, or no active warming before anesthesia. All three groups will receive warming during surgery as part of routine care.

Warming will be provided using a forced-air warming system. After surgery, a sensor placed on a finger will measure the perfusion index, a noninvasive indicator of blood flow, on arrival in the recovery unit and 5 and 10 minutes later. The main comparison will use the average of these three measurements. The researchers will also assess other circulation measurements, routine blood gas and lactate results, shivering, pain, the time until oral feeding begins, and wound infection during the 14 days after surgery.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Age 18 years or older. * Scheduled for elective colon resection surgery under general anesthesia. * American Society of Anesthesiologists (ASA) physical status I-III. * Willing to participate and able to provide written informed consent. Exclusion Criteria: * Age younger than 18 years. * Emergency surgery. * Severe vascular disease that may affect peripheral circulation, such as advanced peripheral arterial disease. * Severe cardiovascular instability. * Fever (\>38 degrees Celsius) or hypothermia (\<36 degrees Celsius) before surgery. * Severe anemia (hemoglobin \<8 g/dL). * Requirement for vasopressor or inotropic support. * A condition in the measurement limb that prevents perfusion index measurement, such as severe peripheral edema, an intravenous line, or involvement of the surgical field. * Refusal to participate.

Primary outcome measure(s)

  • Mean Postoperative Perfusion Index — At PACU admission and 5 and 10 minutes after admission
    Perfusion index (PI) is measured noninvasively using a pulse oximeter at postanesthesia care unit (PACU) admission, 5 minutes, and 10 minutes. The primary outcome is the arithmetic mean of these three measurements. PI reflects the ratio of the pulsatile to nonpulsatile component of the photoplethysmographic signal and is used as an indicator of peripheral perfusion.

Trial sites (1)

FacilityCityRegionStatus
Kayseri City Hospital Kayseri Turkey (Türkiye)

More Çiğdem Ünal Kantekin trials in Turkey

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07857538 on ClinicalTrials.gov ↗ ← All trials in Turkey