Continuous Adductor Canal Block (CACB) Combined With İnfiltration Between the Popliteal Artery and Capsule of the Knee (iPACK) Block vs Continuous Adductor Canal Block Alone After Total Knee Arthroplasty
IPACK block: Single injection of 0.25% bupivacaine 20 mL between the popliteal artery and posterior knee capsule, performed under ultrasound guidance
Continuous adductor canal block (CACB): Perineural catheter placement in the adductor canal with PCA-delivered 0.1% bupivacaine (5-7 mL basal rate, 5 mL bolus, 30-min lockout) for 24 hours postoperatively
Study summary
This study compares the effects of adding an infiltration between the popliteal artery and capsule of the knee (iPACK) block to a continuous adductor canal block (CACB) versus continuous adductor canal block alone on postoperative analgesia, opioid consumption, early mobilization, and length of hospital stay in patients undergoing total knee arthroplasty. This is a prospective, randomized, double-blind study with 54 patients allocated 1:1 into two groups.
Eligibility
Sex
ALL
Min age
18 Years
Max age
75 Years
Healthy volunteers
No
Inclusion Criteria:
* Patients of either sex
* Aged 18 to 75 years
* American Society of Anesthesiologists (ASA) physical status I, II, or III
* Voluntary participation
* Fully oriented and able to cooperate with postoperative assessments
Exclusion Criteria:
* ASA physical status IV or V
* Patients who decline to participate
* Pediatric patients
* Active infection at the block site
* Chronic pain or regular analgesic use
* Coagulation disorders
* Inability to cooperate with postoperative pain assessment
* Known allergy to local anesthetics
* Neuropathy or myopathy in the operated extremity
* Revision arthroplasty cases
Primary outcome measure(s)
Postoperative Pain Score (Numeric Rating Scale) — Baseline and postoperative hours 1, 3, 6, 12, and 24 Pain intensity assessed using the Numeric Rating Scale (NRS, 0-10; 0 = no pain, 10 = worst pain imaginable)
Trial sites (1)
Facility
City
Region
Status
Basaksehir Çam Ve Sakura City Hospital, İstanbul, Türkiye
Başakşehir
Istanbul
More Başakşehir Çam & Sakura City Hospital trials in Turkey
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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