RISS Versus SPSIP Block in Modified Radical Mastectomy

NCT07659990 · tracked via the Priya Life Science Turkey tracker

Sponsor

Ferit Yetik

Phase

Not applicable

Started

2026-06-19

Last updated

2026-06-24

Condition(s) studied

Postoperative PainBreast Cancer

Investigational drug(s) / intervention(s)

Rhomboid Intercostal-Subserratus Plane BlockSerratus Posterior Superior Intercostal Plane Block

Rhomboid Intercostal-Subserratus Plane Block: Ultrasound-guided rhomboid intercostal-subserratus plane block performed before modified radical mastectomy for postoperative analgesia.

Serratus Posterior Superior Intercostal Plane Block: Ultrasound-guided serratus posterior superior intercostal plane block performed before modified radical mastectomy for postoperative analgesia.

Study summary

This prospective randomized double-blind controlled trial aims to compare the postoperative analgesic efficacy and dermatomal spread of rhomboid intercostal-subserratus plane (RISS) block and serratus posterior superior intercostal plane (SPSIP) block in patients undergoing modified radical mastectomy. Postoperative pain scores, opioid consumption, rescue analgesic requirements, block-related complications, and quality of recovery outcomes will be evaluated.

Eligibility

Sex

FEMALE

Min age

18 Years

Max age

75 Years

Healthy volunteers

Inclusion Criteria: * Female patients aged 18-75 years * ASA physical status I-III * Scheduled for elective unilateral modified radical mastectomy with axillary dissection under general anesthesia * Provision of written informed consent Exclusion Criteria: * Anticoagulant therapy * Bleeding diathesis * Known allergy to local anesthetics or opioids * Infection at the block application site or previous surgery in the block area * Cognitive impairment preventing NRS assessment * Pregnancy or lactation * Chronic opioid use * Severe hepatic or renal failure * Refusal to participate in the study * Technical inability to perform the block or failed block

Primary outcome measure(s)

Total Postoperative Opioid Consumption — 24 hours after surgery
Total opioid consumption during the first 24 hours after modified radical mastectomy.

Trial sites (1)

Facility	City	Region	Status
Bursa City Hospital	Bursa	Nilüfer	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07659990 on ClinicalTrials.gov ↗ ← All trials in Turkey