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Active, not recruiting Not applicable

Effects of Pulmonary Rehabilitation Exercises in Patients With Axial Spondyloarthritis

NCT07847879 · tracked via the Priya Life Science Turkey tracker
Phase
Not applicable
Started
2025-11-10
Last updated
2026-09-29

Condition(s) studied

Axial SpondyloarthritisAnkylosing Spondylitis (AS)

Investigational drug(s) / intervention(s)

Pulmonary Rehabilitation ProgramConventional Exercise Program

Pulmonary Rehabilitation Program: The pulmonary rehabilitation program was administered for 8 weeks in addition to conventional exercise. Participants performed home-based breathing and range-of-motion exercises twice daily for 10 repetitions. Breathing exercises included pursed-lip breathing, diaphragmatic breathing, lateral abdominal breathing, relaxation and breathing control exercises, and neck and shoulder stretching. Participants also performed supervised cycle ergometer exercise twice weekly for 30 minutes per session, including warm-up and cool-down periods, together with upper-extremity and shoulder-girdle strengthening exercises.

Conventional Exercise Program: Participants performed a home-based conventional exercise program. Exercise instructions were provided through a video recording, and participants attended face-to-face follow-up sessions once weekly.

Study summary

This prospective, randomized, single-blind controlled study evaluates the effects of pulmonary rehabilitation exercises in patients with axial spondyloarthritis. Participants were randomized into two groups. The intervention group received a pulmonary rehabilitation program in addition to conventional exercises, while the control group received conventional exercises alone. The primary outcome was pain intensity assessed using the Visual Analog Scale (VAS). Additional assessments included exercise capacity, pulmonary function, disease activity, quality of life, spinal mobility, and chest expansion. Outcomes were evaluated at baseline, week 8, and week 12.

Eligibility

Sex
ALL
Min age
18 Years
Max age
60 Years
Healthy volunteers
No
Inclusion Criteria: * Age between 18 and 60 years. * Fulfillment of the Assessment of SpondyloArthritis international Society (ASAS) classification criteria for spondyloarthritis and/or diagnosis of ankylosing spondylitis according to the Modified New York criteria. * Willingness to participate in the study and provision of informed consent. Exclusion Criteria: * Presence of a respiratory or cardiovascular disease that may affect exercise capacity, including chronic obstructive pulmonary disease, asthma, cardiac arrhythmia, or heart failure. * Recent surgery that prevents participation in the exercise program. * Upper-extremity musculoskeletal injury or history of thoracic trauma that may interfere with the exercise program. * Chronic neuromuscular or musculoskeletal disease limiting upper-extremity function. * Obesity, malignancy, or epilepsy. * Pregnancy or breastfeeding. * Severe contractures or axial deformities, including chest deformity, advanced kyphosis greater than 40 degrees, scoliosis, or rotoscoliosis. * Neurological or psychiatric disorders, including ongoing depression, that may interfere with participation in the study.

Primary outcome measure(s)

  • Change in Pain Intensity Assessed by Visual Analog Scale (VAS) — Baseline, Week 8, and Week 12
    Pain intensity is assessed using a 0-10 cm Visual Analog Scale (VAS), where 0 indicates no pain and 10 indicates the worst imaginable pain. Changes from baseline are evaluated at Week 8 and Week 12, with Week 12 defined as the primary endpoint.

Trial sites (1)

FacilityCityRegionStatus
Sisli Hamidiye Etfal Training and Research Hospital Istanbul Istanbul
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07847879 on ClinicalTrials.gov ↗ ← All trials in Turkey