Renal Doppler Ultrasonography: Bilateral renal Doppler examinations are performed at T0 (one day before surgery after at least 10 minutes of rest), T1 (within the first 60 minutes after postoperative ICU admission), and T2 (6 hours after ICU admission). Renal augmented velocity index and renal resistive index are calculated offline from stored waveforms. Study measurements do not guide clinical care.
Study summary
Acute kidney injury can occur after coronary artery bypass grafting (CABG). This prospective, single-center observational study will evaluate whether two measurements obtained from renal Doppler ultrasound-the renal augmented velocity index (AVI) and renal resistive index (RRI)-can help predict postoperative acute kidney injury. About 200 adults undergoing elective isolated CABG with cardiopulmonary bypass will have bilateral renal Doppler examinations one day before surgery, within 60 minutes after admission to the intensive care unit, and 6 hours after intensive care unit admission. The primary outcome is acute kidney injury within the first 7 days after surgery, defined according to Kidney Disease: Improving Global Outcomes (KDIGO) criteria. Ultrasound measurements will be analyzed offline and will not influence clinical care.
Eligibility
Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria:
* Age 18 years or older.
* Scheduled for elective isolated coronary artery bypass grafting with cardiopulmonary bypass (on-pump).
* Able and willing to provide written informed consent.
* Both kidneys present.
* Adequate bilateral preoperative renal Doppler signal for study measurements.
Exclusion Criteria:
* Preoperative chronic dialysis or renal replacement therapy.
* Urgent or emergency surgery.
* Combined cardiac surgery, including valve, aortic, or another major additional procedure.
* Off-pump coronary artery bypass grafting or conversion of the planned surgical technique.
* Clinically significant rhythm disturbance preventing acquisition of three interpretable cardiac cycles.
* Renal transplant, solitary kidney, significant renal artery stenosis, previous renal artery intervention, hydronephrosis, or other relevant renal vascular or structural disease.
* Inadequate bilateral preoperative renal Doppler examination.
* Withdrawal of consent.
Primary outcome measure(s)
Incidence of Acute Kidney Injury According to KDIGO Criteria — From surgery through postoperative day 7 Number and percentage of participants who develop acute kidney injury according to Kidney Disease: Improving Global Outcomes (KDIGO) criteria, based on serum creatinine and/or urine output.
Trial sites (1)
Facility
City
Region
Status
Bursa Yuksek Ihtisas Training and Research Hospital
Bursa
Bursa
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This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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