Effect of Amniotic Fluid Odor on Newborn Adaptation and Stress (AFO-NAS)

Condition(s) studied

Investigational drug(s) / intervention(s)

Amniotic Fluid Odor Sterile Distilled Water Odor: In the intervention group, healthy newborns born by cesarean section will be exposed to the odor of their own amniotic fluid shortly after birth. Amniotic fluid collected during delivery will be applied to a sterile material and positioned near the newborn's nose without direct contact with the skin or airway. The intervention will be administered according to a standardized study protocol. The newborns' postnatal adaptation, physiological parameters, and stress responses will be assessed at predetermined time points.

Study summary

This study aims to determine whether exposure to the odor of a newborn's own amniotic fluid affects postnatal adaptation and stress in healthy newborns born by cesarean section. Newborns will be randomly assigned to either an intervention group or a control group. Newborns in the intervention group will be exposed to a sterile material moistened with their own amniotic fluid, while newborns in the control group will be exposed to a sterile material moistened with distilled water. Postnatal adaptation, physiological responses, and stress levels will be evaluated at predetermined time points.

Eligibility

Primary outcome measure(s)

• Heart Rate:beats per minute — At 30 minutes after birth
  The newborn's heart rate will be measured using a pulse oximeter and recorded as beats per minute. Heart rate values will be compared between the amniotic fluid odor group and the sterile distilled water odor group.
• Respiratory Rate: breaths per minute — At 30 minutes after birth
  The newborn's respiratory rate will be assessed by counting respiratory movements for one minute and recorded as breaths per minute. Respiratory rate values will be compared between the study groups.
• Peripheral Oxygen Saturation:percentage — At 30 minutes after birth
  The newborn's peripheral oxygen saturation will be measured using a pulse oximeter and recorded as a percentage. Oxygen saturation values will be compared between the study groups.
• Body Temperature: degrees Celsius — At 30 minutes after birth
  The newborn's body temperature will be measured using a digital thermometer and recorded in degrees Celsius. Body temperature values will be compared between the study groups.

Trial sites (1)

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