Ireland
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Recruiting Observational

Relationship Between Induction Burst Suppression and Bispectral Index

NCT07557433 · tracked via the Priya Life Science Turkey tracker
Phase
Observational
Started
2026-07-01
Last updated
2026-07-06

Condition(s) studied

Bispectral Index MonitoringBurst SuppressionTotal Intravenous Anesthesia

Study summary

The purpose of this study is to understand whether certain brain activity patterns that can appear at the beginning of anesthesia are related to how deep anesthesia remains during the operation.

The main question of the study is:

Do patients who show a pattern called burst suppression during the start of anesthesia experience deeper anesthesia during surgery?

Patients who are scheduled for elective surgery under total intravenous anesthesia (TIVA) may take part in this study. During the operation, brain activity will be monitored using a sensor placed on the forehead (Bispectral Index, BIS monitor), which is already commonly used during anesthesia. Information such as BIS values and the doses of anesthesia medications given during the operation will be recorded.

Participation in this study will not change the type of anesthesia or the routine care that patients receive during surgery. The study only involves recording and analyzing information collected during standard anesthesia monitoring.

Eligibility

Sex
ALL
Min age
18 Years
Max age
75 Years
Healthy volunteers
No
Inclusion Criteria: * Age between 18 and 75 years * American Society of Anesthesiologists (ASA) physical status I-III * Scheduled for elective surgery * Surgery planned to be performed under total intravenous anesthesia (TIVA) Exclusion Criteria: * Presence of neurological disease * Chronic use of sedative medications or antiepileptic drugs * Severe hepatic or renal dysfunction * Intraoperative administration of ketamine or dexmedetomidine

Primary outcome measure(s)

  • TBIS<40 — During intraoperative period
    Total duration during the maintenance phase of anesthesia in which the BIS remains below 40, expressed as a proportion of total surgical time, compared between patients with and without burst suppression during induction

Trial sites (2)

FacilityCityRegionStatus
Amasya University Sabuncuoglu Serefeddin Training and Research Hospital Amasya Amasya Recruiting
Izmir Katip Celebi University Ataturk Training and Research Hospital Izmir İzmir Not Yet Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07557433 on ClinicalTrials.gov ↗ ← All trials in Turkey