Ireland
--:--IST
Latest
Astellas Expands Its 330 Million Euro Tralee Biopharma Facility with a Second Aseptic Filling Line to Double Drug-Product Capacity Xeolas Pharmaceuticals Opens 158,000 Sq Ft State-of-the-Art Baldoyle Facility to Scale Specialty Medicine Manufacturing Priya Life Science Partners with Fleming for the 9th Annual Corporate Compliance & Transparency in Life Sciences Summit in Zurich Ireland Has the Capital and the Lessons: Digital Project Management Is How They Become Delivery Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide The €100K Reality Check: Why a Six-Figure Pharma Salary in Ireland Feels Different Than in Switzerland or Germany Ireland's €93.8 Billion Non-EU Pharma Export Engine: Trade Data, Destination Markets, and Economic Impact Astellas Expands Its 330 Million Euro Tralee Biopharma Facility with a Second Aseptic Filling Line to Double Drug-Product Capacity Xeolas Pharmaceuticals Opens 158,000 Sq Ft State-of-the-Art Baldoyle Facility to Scale Specialty Medicine Manufacturing Priya Life Science Partners with Fleming for the 9th Annual Corporate Compliance & Transparency in Life Sciences Summit in Zurich Ireland Has the Capital and the Lessons: Digital Project Management Is How They Become Delivery Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide The €100K Reality Check: Why a Six-Figure Pharma Salary in Ireland Feels Different Than in Switzerland or Germany Ireland's €93.8 Billion Non-EU Pharma Export Engine: Trade Data, Destination Markets, and Economic Impact
Clinical Trials in Turkey / NCT07508371
Starting soon Not applicable

Menthol Massage for Post-Bypass Pain & Anxiety

NCT07508371 · tracked via the Priya Life Science Turkey tracker
Sponsor
Istanbul Medipol University Hospital
Phase
Not applicable
Started
2026-09-25
Last updated
2026-04-02

Condition(s) studied

Bypass, Cardiopulmonary

Investigational drug(s) / intervention(s)

Menthol MassageMassage

Menthol Massage: A 15-minute back massage with mentholated ointment will be applied after coronary bypass surgery.

Massage: A 15-minute back massage with paraffin oil will be administered after coronary bypass surgery.

Study summary

This randomized controlled trial aims to evaluate the effectiveness of mentholated ointment massage in reducing pain and anxiety levels in patients who have undergone coronary bypass surgery, volunteered to participate in the study, and met the inclusion criteria.

Group 1: Back massage with mentholated ointment (Vicks) Group 2: Back massage with paraffin oil Group 3 (Control): Routine clinical treatment The comparison group consists of the group receiving a back massage with paraffin oil and the control group (routine clinical treatment).

The questions it aims to answer are:

H1: Back massage with mentholated ointment after coronary artery bypass graft surgery reduces back pain levels compared to patients receiving routine treatment.

H2: Back massage with paraffin oil after coronary artery bypass graft surgery reduces back pain levels compared to patients receiving routine treatment.

H3: Back massage with mentholated ointment after coronary artery bypass graft surgery reduces anxiety levels compared to patients receiving routine treatment.

H4: Back massage with paraffin oil after coronary artery bypass graft surgery reduces anxiety levels compared to patients receiving routine treatment.

H5: Back massage with mentholated ointment after coronary artery bypass graft surgery reduces back pain levels compared to back massage with paraffin oil.

H6: Back massage with mentholated ointment after coronary artery bypass graft surgery reduces anxiety levels compared to back massage with paraffin oil.

Pain intensity and vital signs will be monitored in all participants before surgery, at 0 minutes (before analgesia administration), and at 30 minutes after surgery. Additionally, vital signs will be observed before the back massage at 0 minutes and after at 15 minutes. Anxiety levels will be measured before surgery and 15 minutes after the back massage application. A total of 5 back massage applications will be performed until the patients are discharged.

Eligibility

Sex
ALL
Min age
—
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Willing to participate in the study, * Who has undergone bypass surgery, * Aged 18 years or older, * No visual impairment (except those who can see better with visual aids), hearing impairment (except those who can hear better with hearing aids), or speech impairment/communication problems that would prevent them from understanding the information provided and accurately describing their pain, * Literate, * Possesses orientation to person, place, and time, * Has a sternum exposure time of at least 2 hours during surgery, * Does not use any complementary alternative medicine methods, * Meets ASA 1 and ASA 2 criteria, * Elective (planned) surgery patients will be included. Exclusion Criteria: * Individuals with allergies to menthol ointment and paraffin oil used during the procedure, * Individuals participating in a different study conducted at the clinic, * Individuals experiencing confusion, * Individuals with physical and cognitive problems that prevent massage from being applied, * Individuals diagnosed with mood disorders (depression, panic attacks, dysthymia, bipolar disorder, or taking any medication for these conditions), * Individuals with respiratory problems, * Individuals who cannot speak Turkish, and cannot read or write Turkish * Transferred to intensive care during the postoperative period, * Experiencing severe bleeding, hematoma, seroma, or nerve injury during the postoperative period, * Developing an allergy to mentholated ointment/paraffin oil used during massage, * Voluntarily requesting to leave the job, * Individuals who do not comply with the work process and conditions will be removed from the study.

Primary outcome measure(s)

  • The effect of massage intervention after coronary bypass surgery on pain levels will be evaluated at 0 and 15 minutes. — Patients undergo treatment in the ward for 5 days after coronary bypass surgery. Massage therapy will be administered for a total of 5 days until discharge.
    The effect of massage intervention after coronary bypass surgery on pain levels will be assessed at 0 and 15 minutes. The NRS scale will be used to assess pain, with 0 indicating no pain and 10 indicating the highest level of pain.
  • Anxiety — The effect of massage on anxiety levels in patients following coronary bypass surgery will be measured using the State Anxiety Scale 15 minutes after massage. Patients remain in the ward for 5 days after surgery and are then discharged.
    Anxiety will be assessed 15 minutes after each massage session using the State Anxiety Scale. Scores range from 20 to 80, with lower scores indicating less anxiety and higher scores indicating greater anxiety.

Trial sites (1)

FacilityCityRegionStatus
Dr. Siyami Ersek Chest Heart and Vascular Surgery Training and Research Hospital Istanbul Turkey (Türkiye)

More Istanbul Medipol University Hospital trials in Turkey

Paraffin Oil for Preventing Tourniquet-Related Skin Lesions in Upper Extremity Surgery Recruiting
Comparison of PR Efficiency in Home-based With Hospital-based PR in Bronchiectasis Recruiting
Quadro-Iliac Plane Block for Pain Control After Posterior Spinal Instrumentation Surgery Starting soon
IASTM Effects on Pain, Functionality, and Proprioception in Subacromial Impingement Recruiting
Mechanical Properties of Peripheral and Accessory Respiratory Muscles in Chronic Obstructive Pulmonary Disease Patients Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07508371 on ClinicalTrials.gov ↗ ← All trials in Turkey