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Recruiting Observational

Respiratory Function and Oxygenation in Smokers and Non-smokers

NCT07027956 · tracked via the Priya Life Science Turkey tracker
Phase
Observational
Started
2025-05-28
Last updated
2025-06-19

Condition(s) studied

Smoking, Tobacco

Study summary

This study aimed to compare respiratory function, exercise capacity, and intercostal muscle oxygenation in healthy smokers and non-smokers.

Eligibility

Sex
ALL
Min age
18 Years
Max age
65 Years
Healthy volunteers
Accepted
Inclusion Criteria (Smokers): * According to the World Health Organization and ICD smoking addiction criteria, consuming at least one cigarette every day for the last year * Volunteering to participate in research * Able to walk and cooperate Exclusion Criteria (Smokers): * Having any cardiopulmonary disease * Having a musculoskeletal problem that could affect the tests * Failure to comply with tests Inclusion Criteria (Non-smokers): * According to the World Health Organization and ICD smoking addiction criteria, having never smoked or not having smoked in the last year * Volunteering to participate in research * Able to walk and cooperate Exclusion Criteria (Non-smokers): * Having any cardiopulmonary disease * Having a musculoskeletal problem that could affect the tests * Failure to comply with tests

Primary outcome measure(s)

  • Forced vital capacity — 1st day
    Forced vital capacity (FVC) will be assessed using spirometry.
  • Forced expiratory volume in one second — 1st day
    Forced expiratory volume in one second (FEV1) will be assessed using spirometry
  • Forced expiratory volume in one second/forced vital capacity ratio — 1st day
    Forced expiratory volume in one second/forced vital capacity ratio will be assessed using spirometry.
  • Peak expiratory flow — 1st day
    Peak expiratory flow (PEF) will be assessed using spirometry.
  • Forced mid-expiratory flow — 1st day
    Forced mid-expiratory flow (FEF25-75) will be assessed using spirometry.
  • Inspiratory muscle strength — 1st day
    Strength index will be evaluated.
  • Exercise capacity — 2nd day
    will be evaluated with 6 minute walk test and total distance will be recorded.
  • Intercostal muscle oxygenation — 2nd day
    During the 6-minute walking test, oxygenation of the intercostal muscles will be evaluated with a monitor.

Trial sites (1)

FacilityCityRegionStatus
Kirsehir Ahi Evran University Kırşehir Turkey (Türkiye) Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07027956 on ClinicalTrials.gov ↗ ← All trials in Turkey