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Recruiting Observational

Dubousset Functional Test: an Investigation of Its Validity and Reliability in Individuals with Multiple Sclerosis

NCT06849882 · tracked via the Priya Life Science Turkey tracker
Phase
Observational
Started
2025-02-10
Last updated
2025-03-03

Condition(s) studied

MS (Multiple Sclerosis)

Study summary

Multiple sclerosis (MS) is an autoimmune disease characterized by neuroinflammation and neurodegeneration in the central nervous system. The disease affects the white matter, cortex and deep gray matter of the central nervous system and is characterized by inflammatory-demyelinating lesions and neuronal/axonal degeneration. Demyelination associated with these lesions and the accompanying axonal degeneration are responsible for neurological disability in MS. There are many scales and mobility and functional performance tests in the literature to assess balance, such as the Sit Reach Test, Timed Up and Go (TUG) test, Tinetti Performance Oriented Mobility Assessment (POMA), Berg Balance Scale (BBS) (5) and Balance Evaluation System Test (BESTest). The most appropriate balance assessment scales for individuals with MS are those that assess static and dynamic sitting balance while standing and dynamic balance only. Since balance in individuals with MS is a dynamic process that changes gradually, new measurement methods that can record these changes and determine the appropriate treatment for these variables are needed.

The Dubousset Functional Test (DFT) was developed by Dr. Jean Dubousset as a four-component practical assessment to evaluate the physical function and balance capacity of individuals with spinal deformity. The DFT consists of four components: getting up from an armless chair and walking 5 meters forward and backward, ascending and descending steps, transition from standing to sitting position, and gait assessment with a dual task test (counting backwards from 50). The difference of this test from the others is that it evaluates the spinopelvic muscle groups that are directly related to functionality, maintains the global trunk alignment of the individual and provides objective results about functional performance and balance. In addition, unlike other functional performance tests, the DFT assesses the neurophysiological effects of the process that requires individuals to perform two tasks at the same time by measuring their coordination, balance, attention and thinking skills during functioning through a dual task component. The validity and reliability of this test has been previously investigated in low back pain, stroke, parkinson's disease, elderly individuals and hemiplegia. In this study, it was aimed to examine the validity and reliability of the Dubousset functional test in individuals with multiple sclerosis.

Eligibility

Sex
ALL
Min age
18 Years
Max age
65 Years
Healthy volunteers
No
Inclusion Criteria: * Being diagnosed with MS, * Over 18 years of age and under 65 years of age, * To be able to balance independently in standing position. * EDSS score of 3.5 and below * At the appropriate cognitive level to adapt to the tests to be performed in the study, * Completed primary school level, Exclusion Criteria: * Relapse within the last 30 days, * Loss of balance or gait disturbance affected by a condition other than MS, * Being pregnant for female individuals, * An attack of optic neuritis in the last month * Individuals who are unable to perform the task due to sensory, cognitive or other problems will be excluded.

Primary outcome measure(s)

  • Dubousset Functional Testing in Individuals with MS — Day 1
    The aim of this study is to investigate the validity and reliability of the Dubousset functional test in individuals with multiple sclerosis.The Dubousset Functional Test consists of four components; 1. Get Up and Walk Test: Individuals with MS will stand up unassisted from a seated position in a chair without arms, walk 5 meters (500 cm), turn around, walk back 5 meters and sit down again unassisted. 2. Step Test: individuals with MS will climb three steps of stairs from a starting position 50 cm away, turn around on the third step and walk back down. 3. Sit and stand test: Individuals with MS will sit on the floor from a standing position with assistance if necessary and stand up again with assistance if necessary. 4. Dual Task Test: Individuals with MS will walk 5 meters forward, turn around and walk 5 meters backward while performing a memory exercise (counting down from 50 in 2 intervals).

Trial sites (1)

FacilityCityRegionStatus
Erciyes University Kayseri Kayseri Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06849882 on ClinicalTrials.gov ↗ ← All trials in Turkey