The Effect of Glucomannan Powder on Improving Gut Microbiota.

Condition(s) studied

Investigational drug(s) / intervention(s)

Glucomannan: 2 packs of glucomannan, 2 grams per pack

Placebo: 2 packs of corn starch, 2 grams per pack

Study summary

The object of this study is evaluating the effects of the Glucommanan on the healthy human subjects who are. In this trial, at most 30 healthy subjects whose ages are 20\~65 years old (15 for placebo and 15 for intervention)will be included. The total experiment will be 9 weeks and the intervention period will be 6 weeks, within which, at week 0, 6, and 7, total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), aspartate aminotransferase (AST, also known as GOT), alanine aminotransferase (ALT, also known as GPT), blood urea nitrogen (BUN), serum creatinine (Cr), fasting blood glucose (Glucose, AC) and adiponectin would be measured. Feces samples and anthropometric data will also be acquired. The results will be analyzed according to the methods published by the Ministry of Health and Welfare of Taiwan Food and Drug Administration.

Eligibility

Primary outcome measure(s)

• gut microbiota — Week(0) (Baseline), Wk(6),Wk7
  Evaluation of Gut Microbiota by Analysis of Four Indicator Strains and 16S rRNA Sequencing Using Fecal Samples

Trial sites (1)

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