Effect of Dialysis-specific Therapeutic Diet on Biochemical Parameters in Dialysis Patients

Condition(s) studied

Investigational drug(s) / intervention(s)

Dialysis-specific therapeutic diet: A healthy diet for dialysis patients

Study summary

In patients with kidney failure, disturbances in bone turnover, mineral metabolism, vascular calcification, uremia, inflammation, immunity, metabolomics, nutrition, and gut microbial metabolites are frequent. Unhealthy diet causes altered mineral metabolism, elevated uremic toxin level, immune dysregulation, metabolic abnormalities, inflammation, protein-energy wasting and dysbiosis. The investigators hypothesize that therapeutic diet intervention reverses these uremic complications and thereby reduces cardiovascular risk in patients with kidney failure. In this study, the investigators crafted 4-week dialysis-specific therapeutic diet to illustrate the clinical implications of therapeutic diet for dialysis patients.

Eligibility

Primary outcome measure(s)

• Concentrations of intact fibroblast growth factor 23 (pg/mL) — 4 weeks
  Difference in change-from-baseline intact fibroblast growth factor 23 (pg/mL) between therapeutic diet and usual diet

Trial sites (1)

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