Efficacy/Safety of Midurethral Sling

Condition(s) studied

Investigational drug(s) / intervention(s)

Urodynamic investigations before and after a trans-obturator tape protocol.: Urodynamic investigations (The urodynamic study included free uroflowmetry, postvoid residual, filling and voiding cystometry, and a urethral pressure profile. The filling cystometry and urethral pressure profile were performed with 37 degrees C normal saline similar to body temperature at an infusion rate of 80 ml/min.)

Urodynamic investigations before and after a tension-free vaginal tape-obturator (TVT-O): Urodynamic investigations (stated above.)

Urodynamic investigations before and after a mini Arc protocol.: Urodynamic investigations (stated above)

Urodynamic investigations before and after an i-STOP mini adjustable sling protocol.: Urodynamic investigations (stated above)

Urodynamic investigations before and after an Solyx sling protocol.: Urodynamic investigations (stated above.)

Study summary

The trans-obturator tape (TOT), which exhibits a satisfactory cure rate and a relatively diminished invasiveness, has been increasingly accepted as a surgical treatment of stress urinary incontinence (SUI) patients. Nevertheless, in contrast to the well-recognized therapeutic benefit of the enhanced resistance to the bladder continence during urine storage, if the voiding function of the bladder adapts to the TOT-enhanced outlet resistance has not been adequately investigated. This study retrospectively assayed the voiding efficacy of each voiding cycle, to clarify if the thermodynamic efficacy of the bladder was modified in response to the TOT surgery.

Eligibility

Primary outcome measure(s)

• Pressure-volume study — within a voiding cycle (a cycle is about 30 to 60 minutes)
  urine leakage.

Trial sites (1)

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